Aips019838.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Agrotis ipsilon
Gene Symbol
-
Assembly
GCA_028554685.1
Location
CM052974.1:4812399-4825431[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 4.5e-05 0.0046 18.3 6.9 1 23 176 198 176 198 0.98
2 13 6.5e-07 6.5e-05 24.1 0.3 2 23 211 232 211 232 0.97
3 13 7.1e-05 0.0072 17.7 2.0 2 23 241 262 241 262 0.98
4 13 0.00029 0.029 15.8 1.5 3 23 270 290 268 290 0.95
5 13 5.9e-06 0.0006 21.1 1.5 1 23 296 318 296 318 0.98
6 13 1.2e-05 0.0012 20.1 8.5 2 23 325 346 324 346 0.97
7 13 2.3e-05 0.0023 19.2 0.8 1 23 352 374 352 374 0.98
8 13 2.3e-06 0.00024 22.3 1.5 1 23 380 402 380 402 0.99
9 13 0.0061 0.62 11.6 2.3 1 23 408 430 408 430 0.98
10 13 0.00039 0.04 15.3 1.2 1 23 436 458 436 458 0.97
11 13 9.1e-06 0.00092 20.5 1.2 1 23 464 486 464 486 0.98
12 13 2.4e-06 0.00024 22.3 0.7 1 23 492 514 492 514 0.99
13 13 0.00024 0.024 16.0 2.7 1 23 576 598 576 598 0.99

Sequence Information

Coding Sequence
ATGGCTGCTCCCATTAAACCTTTGAAATTCGACAAAATATGTCGCGCCTGTTTAGAGATAAAAAAGGATATGAGACCCCTATTTGATCAACTCACAGCGACGATGCTGATGGGCATATCGAAAGTGCAGGTGGCAGTAGGCGATGGACTACCTCCTCAGCTGTGTCTCCAGTGCGTGCACCAGATATCTCGGTGCCACGCCTTCAAGGACCTGGTGGAGAGGAACGACATTACGCTGCGGGAGCATGCTGCCAGGATGGCAGAGGAGGTCTTCAAGAGGGAGAGGGAGGAGAAAGAGAAGATGTTAACCCTGAACTGCACGGAGCCGTACATGCAGTACATGGAGGTTCCTCTCACCAACACCAGCCAGATCCTGGACGGGTTCTTCACCGCCACGCCTGAGCAGCCACCCGCGGAGACGCCTGACACCGAACTTAAACCAGACTTCGCGGCTGAGAAGGTATATTTGTTACAAGGAACCCAACTGGTGTTATTCCAAGCGACCTCCACGGTGTCTCCCGGACGTCACGTATGCAACCTCTGCCATAAGGAGTTCAAACATGCACGGTGGCTAAAGCAGCATATGAGATCTCATACCAACTGGATCAAGGCAAACTGTAAGAAGCCGCCCAGTTGCCCCATCTGCGATAGAACTTTCAAGGGCCCCGGCATGCTGAAGATGCACATGCGCACGCACGAGGCGCGGCCCGCCAAGCAGCCCACGTGCTCGGTGTGCCAGCGCACGTTCCCCAGCAAGACGCTGCTGTACCGCCACCGACAGACGCACTTCGAGCAGAAGACGCACCTGTGCTCCGTGTGCGACAAGCGCTTCTACAGCGGGTACGCGCTGCGCTCGCACATGGCGCGCCATCGAGGAGAGAGGCCCTACGTCTGCACCACCTGCAACAAGAGCTTCTACAACCCCACGGACCTGAAGGTTCACTTCCGCCTGCACACAGGCGAGAAGCCGCTGAAATGTAACGAGTGCAACAAGACATTCAGGCGACATTCGACCTTGTGCCAACACATGAAGAAACACCGCGGCATACGGAACCACGTGTGCACTGTCTGCAACAAGGGATTCTACGAGGTGTCCAAGTTGAATGCGCATATGAGGGTCCATACTGGCGAGAGGCCGTACGAGTGTCAGTACTGCTCGCGTCGCTTCGCGCAGCAGTCGGCCCTCATCTACCACCGGCGCACGCACACGGGCGAGAAGCCCTACTGCTGCAAGCTGTGCGCCGCCAGGTTCACCACGTCCTCCGCCCGGAACAACCACATGGTCACGCATACCGGGAACAAGAGGTTCGTGTGTCCGATCTGCCTGAAGGGCTGCACGTCTCGCTCGGAGCTGCGCGTGCACTCCAGCAAGCACACCGGCGAGAAGCTGTTCGAGTGCGGCCAGTGCGGACAGCGGTTCAGCTCGGCCTCGTACCTGGCCGTGCACCGGCGGCACCACTCCGGGGAGAAGAAGTACCAGTGCGCCGTCTGCGGGAAGGGTTACATAGAATCAAGTTCGTACAAGAAGCACATGAAGACGCACGCGAAGTCTGAGACGGAGTCGTCCACGTCGGAGAACAGCGCGGAGGTGCCGCCCGGGAAGGAACCCTGTGTGGAGCACGAGACTATCATCGTCACTGAGGACCTGCCTGAGGCGCAGAACCAAGTTCCGCAAGTCCAGATTCAAGTGCAGAACGAGCGCCCTCCGCAGAAGAAGACAACGCGATACAAGTGCTGGCTGTGTGTGAAGACATACATGTATTTACACAACTTGAAGAAACACATGCTGGTGCATGAACAAGAAAATGGCAGTAACGCAGAACCTGTAATATTCTTACAGCAACAGCAATCACAGCAacagcagcagcaacaacagcaacagcagcagcagcaacaacaacaacagcagcagcaacaacaacaacagcgcCAACAGCAACACCAGCAGCAACAagcacaacaacaacaacaccaACAACAGATGCAACAACATCAAGTGCAACAAGTTCAAGTACAACAACAGCAAGTTCAAGTTCAACAGCAGCAAGTGCAACAACAAGTGCAGCAACAGGTGCAGCATCACCAGCAACAGCAACAGTTGCAGCAGCAAGCCGTGTTGCAGGTCGGCAACGTGCAACAGCTCGCGGTGCCCATACATGCACAACATGTGCAGCAAGGGATTACCGTGTCTGGAGTACAGAGTCAGCACCCATACCCGGTGATCTCTTCGGTGCAGTCGTTACAGCTGCAGCAGACGCAACAGGTTAACACGCAACAGCCGCAGCAACTGCAAGTACAGACCATACAGATACACCCGCAACATCAACCAATACAGATACATGCGGTGGGCGTGCAACAAGTGCAGCAGCAACAGTTGCACGTCGCGACCTCCAGCTGCCAGACCATGCTGCCCAATATACTGCAGTTGCAGCCAGCCACAGTGGCAGTGTCGGGGCTGTCGCAGCAGGAGCTGGGCGGCGTCACGCACCGCATCATCCTGCAGCCGCAGCCCTCCGCCACGCACCCCGCCGTCTACACCATCCACCATTAA
Protein Sequence
MAAPIKPLKFDKICRACLEIKKDMRPLFDQLTATMLMGISKVQVAVGDGLPPQLCLQCVHQISRCHAFKDLVERNDITLREHAARMAEEVFKREREEKEKMLTLNCTEPYMQYMEVPLTNTSQILDGFFTATPEQPPAETPDTELKPDFAAEKVYLLQGTQLVLFQATSTVSPGRHVCNLCHKEFKHARWLKQHMRSHTNWIKANCKKPPSCPICDRTFKGPGMLKMHMRTHEARPAKQPTCSVCQRTFPSKTLLYRHRQTHFEQKTHLCSVCDKRFYSGYALRSHMARHRGERPYVCTTCNKSFYNPTDLKVHFRLHTGEKPLKCNECNKTFRRHSTLCQHMKKHRGIRNHVCTVCNKGFYEVSKLNAHMRVHTGERPYECQYCSRRFAQQSALIYHRRTHTGEKPYCCKLCAARFTTSSARNNHMVTHTGNKRFVCPICLKGCTSRSELRVHSSKHTGEKLFECGQCGQRFSSASYLAVHRRHHSGEKKYQCAVCGKGYIESSSYKKHMKTHAKSETESSTSENSAEVPPGKEPCVEHETIIVTEDLPEAQNQVPQVQIQVQNERPPQKKTTRYKCWLCVKTYMYLHNLKKHMLVHEQENGSNAEPVIFLQQQQSQQQQQQQQQQQQQQQQQQQQQQQQQRQQQHQQQQAQQQQHQQQMQQHQVQQVQVQQQQVQVQQQQVQQQVQQQVQHHQQQQQLQQQAVLQVGNVQQLAVPIHAQHVQQGITVSGVQSQHPYPVISSVQSLQLQQTQQVNTQQPQQLQVQTIQIHPQHQPIQIHAVGVQQVQQQQLHVATSSCQTMLPNILQLQPATVAVSGLSQQELGGVTHRIILQPQPSATHPAVYTIHH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01094252;
90% Identity
iTF_00042852; iTF_00043770; iTF_00040091;
80% Identity
-