Basic Information

Insect: Agrotis exclamationis
Gene Symbol: zfh1
Assembly: GCA_950005045.1
Location: OX465424.1:454682-459932[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.021 2.9 10.0 0.3 1 23 66 88 66 88 0.94

2 8 6.3e-06 0.00086 21.1 2.8 1 23 99 121 99 121 0.98

3 8 1.9e-06 0.00027 22.7 6.2 1 23 130 152 130 152 0.99

4 8 0.00014 0.019 16.9 1.0 1 21 158 178 158 179 0.95

5 8 0.00058 0.079 14.9 0.9 1 20 435 454 435 456 0.93

6 8 1e-05 0.0014 20.4 1.1 1 23 755 777 755 777 0.94

7 8 8.5e-05 0.012 17.5 7.6 1 23 783 805 783 805 0.98

8 8 0.055 7.5 8.7 8.1 1 21 811 831 811 832 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.021	2.9	10.0	0.3	1	23	66	88	66	88	0.94
2	8	6.3e-06	0.00086	21.1	2.8	1	23	99	121	99	121	0.98
3	8	1.9e-06	0.00027	22.7	6.2	1	23	130	152	130	152	0.99
4	8	0.00014	0.019	16.9	1.0	1	21	158	178	158	179	0.95
5	8	0.00058	0.079	14.9	0.9	1	20	435	454	435	456	0.93
6	8	1e-05	0.0014	20.4	1.1	1	23	755	777	755	777	0.94
7	8	8.5e-05	0.012	17.5	7.6	1	23	783	805	783	805	0.98
8	8	0.055	7.5	8.7	8.1	1	21	811	831	811	832	0.96

Sequence Information

Coding Sequence: ATGGTGTCTGCAGTCGGACAGGCGGAGTTTTTTCTTCGAGCAAAGCAAACACTTGGGCGCTCCCCGCCGTACTCCTCGCCGCGCTCCTCGCCGCCCGCCGACACAGTCCGTCCGTTGGCCGGCGGCGGGTCAGAAGGCAAGCCGTCTGAGGAAGAGGAAGAGCGTGGAAGCTCGCCCCTCGGTCCCGGCGGGCCGTTCTCGTGCAGCCAGTGCCGCGGAGCATACCCCACGCGCGAGCAGCTCGAGCGCCACGAGACCCTGCACGCGCCCAACACACAGGTGGATACAGTCAAATATTCATGCAAGATTTGCCACAAAAGCTTCGCAAACGTGTACAGACTGCAGCGGCACATGATCAGCCATGACGAAAGCGCTCTCCTTCGCAAATTTAAGTGCAATGATTGCGACAAGGCTTTTAAATTCAAGCATCACCTAAAAGAACATTTGCGGATACATAGTGGTGAAAAACCCTTTGAGTGCGCTAACTGCGGCAAAAAGTTTTCTCACTCTGGATCCTACTCCAGCCATATGACCTCAAAAAAGTGTCTGGTTATGAATCTCAAGATGGGACGAATTAAACCCAATAATCCTGCACTAAACCCAGAAAGAAGTCCATCAAGGAAAAGAACTAATGCCATGGTGGCCTCccagttaaataataatatatcgcCTAACGGAAATTCTTTCCTACCCATGCCAGCTGCCTTCTTTGCCATGACGGCCCAGGATAATAATTACCATCGCCCGCCCCTAGGGCAGCCTGCAATTTCGCCCTTTTACATGCCTCAGGGCATGCCTATGAGCCCAGCGGGCGGGATATCTCCCTACAGTATACCTGCATCCATCAGCCAATTTTTAGAGCAGCTAGCTTCATCACAGTATCAACCACGAAAAATGGAAAATCCTTCAAGTCCAAAGCCGACAAGTCCTCTGCCAGCAGATCCTGAAGACCTGATTGAAGAAGTTACAGAAGATGATGATAAACGATCTGAAGGAAGCGCTGAGCTTGTGATGGACATAGAAGATGAGGAAGGTGTGTCTATAAAAAAAGAGCAAGAAGAACGAGAAAGCGACTTGAGGTCTCCGTCTCACAACTTCGATTCCGTCCCTTTAAACAACAATGTTCACAACGCCGAAAACCCAGGTTTCAATTCCATACTAGAATCTGTAAGCGCATCCGTAACAAAACACTTCTTTAGAGCAAACATGGAAAAGCTCTCTCCTGTATCAGGTAACATTTGCCCCAGCATAGAGTCACCACCCACTCCTCACGTCGTAATAAAGGAAGAACCAGAAGACACGCACAGATGTTTGAAGTGCAACCTAACTTTCACTAATAAGAGTGACTTATTAGACCACGAAAAAGGACTTTGTGGAAATATGTTTAGAAAACACGAAGGTTTGGCAGCTCAAGTAGCCGAAACGGTAGCTCTTAGATTAGAAGCCGAAATGCATGCTTCAATACAAAACGGAATAAGTGCAAGCGAAGATGAAGACTTTAATAGAGACGATCGCGATGATAAGATATCAATACACGACAATGATAGAAAAATCAGAGTGCGTACAGCACTAAGCGAGGAACAGCAGTCGGTATTGAAAGAACACTACGCATTAAACCCACGACCAAATCGTGAAGAGTTTAAAAGAATAGCTCAACAAATCGGTCTCGACAACAGAGTAGTACAGGTATGGTTCCAAAATAATAGGGCGAGAGAACGACGTATGACACAAACAATGACCGTCTCTGACCAGCCGTTAGATTTATCTACAAAAAAGTCCAATCCATCAGTTACGTCGAGTCCATCGCCATCGCCAACATGTAGCATTTCTGTGACACATTCCGACTCTGAGGAAGCAGTGAACCTCAGTCAGAAATCCTCGCGaagtacaactcctcaacgcaACTATCTGAATACTTATCCACATTCCAACTGCTCGTCATCTTCCTTCACTGACTTTCGATTGTCTCCTTCACCTGGAGAAACTATTAATGGGCACAAACGATTACTACCCCAGAAATTGCATGTCAACCCTTTAGTACCGATGGACAAACTCCTTCAATACAATGATATGGCAAACGCACGATCTCCTATTCTCAACATGCACTTGACCTCAGACATCAGCCGACAAGGTTCAAGTCCATCTTACGAGCGTCCTCCCTGGGATGAAATGCAAGCATCAAACGAGGTCGAAGAAGATGCCACAGTACTTAAGAAGAGCAAACTTAAGCAGGGAGCAGAATTTAAGGAAGGGGAAGGACAATTCGTATGCGATCAGTGTGACAAGACCTTCGTCAAGCAAAGCTCCCTCGCAAGGCACAAATACGAACATTCAGGTCAACGCCCGTATAAGTGTCTAGAATGTCCAAAGGCATTCAAACACAAACATCACTTGACGGAACACAAGCGGCTCCACACTGGTGAGAAGCCTTTCCAGTGCTGCAAGTGCTTCAAGAAATTCTCTCACTCGGGCTCCTACAGTCAACACATGAACCACAGGTTCGCCATCTGCAAGCCCTACCGGGATTAA
Protein Sequence: MVSAVGQAEFFLRAKQTLGRSPPYSSPRSSPPADTVRPLAGGGSEGKPSEEEEERGSSPLGPGGPFSCSQCRGAYPTREQLERHETLHAPNTQVDTVKYSCKICHKSFANVYRLQRHMISHDESALLRKFKCNDCDKAFKFKHHLKEHLRIHSGEKPFECANCGKKFSHSGSYSSHMTSKKCLVMNLKMGRIKPNNPALNPERSPSRKRTNAMVASQLNNNISPNGNSFLPMPAAFFAMTAQDNNYHRPPLGQPAISPFYMPQGMPMSPAGGISPYSIPASISQFLEQLASSQYQPRKMENPSSPKPTSPLPADPEDLIEEVTEDDDKRSEGSAELVMDIEDEEGVSIKKEQEERESDLRSPSHNFDSVPLNNNVHNAENPGFNSILESVSASVTKHFFRANMEKLSPVSGNICPSIESPPTPHVVIKEEPEDTHRCLKCNLTFTNKSDLLDHEKGLCGNMFRKHEGLAAQVAETVALRLEAEMHASIQNGISASEDEDFNRDDRDDKISIHDNDRKIRVRTALSEEQQSVLKEHYALNPRPNREEFKRIAQQIGLDNRVVQVWFQNNRARERRMTQTMTVSDQPLDLSTKKSNPSVTSSPSPSPTCSISVTHSDSEEAVNLSQKSSRSTTPQRNYLNTYPHSNCSSSSFTDFRLSPSPGETINGHKRLLPQKLHVNPLVPMDKLLQYNDMANARSPILNMHLTSDISRQGSSPSYERPPWDEMQASNEVEEDATVLKKSKLKQGAEFKEGEGQFVCDQCDKTFVKQSSLARHKYEHSGQRPYKCLECPKAFKHKHHLTEHKRLHTGEKPFQCCKCFKKFSHSGSYSQHMNHRFAICKPYRD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00281695;
90% Identity: iTF_00171643;
80% Identity: iTF_00040681;