Acla044523.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Agrotis clavis
Gene Symbol
-
Assembly
GCA_954870645.1
Location
OX940947.1:1605109-1606629[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.08 9.8 8.3 0.3 3 23 166 187 165 187 0.93
2 9 0.069 8.5 8.5 0.7 1 23 221 243 221 243 0.96
3 9 0.013 1.6 10.7 0.2 3 21 250 268 248 269 0.91
4 9 6.3e-05 0.0078 18.0 0.5 2 23 291 312 290 312 0.97
5 9 1.4e-05 0.0017 20.1 2.6 1 23 319 341 319 341 0.97
6 9 1.2e-05 0.0015 20.3 0.4 1 23 347 369 347 369 0.98
7 9 3e-05 0.0037 19.1 2.0 1 23 375 397 375 397 0.96
8 9 0.00011 0.013 17.3 3.8 1 23 403 425 403 425 0.98
9 9 2.3e-06 0.00029 22.5 2.1 1 23 431 454 431 454 0.98

Sequence Information

Coding Sequence
ATGAACAACACAGCGAACGTTTACTGCCGTCTTTGTGCTGAGTTGATGCCGCCCAACAAACTCTTCGATCTCCAAACTGACGAAGAAAAATGTCGAGATATCATCATGAAATTGACCCGTTTCAATGTTCAAGTCAACTTCAGCGATAATATATTACCAAAAATGGTCTGTTACACATGTATCATGGGATTAAATCGTACGTTTGAGTTTATTACTGCTGTGGAAAAAGCCCAATCGACTTTAAACGACTTTATTTTAACGAGACAGATAAAACTAGAGAAACCGGGTTCCGACGACGAACTCGTCGTCTACGACTCTTCAGATAGCTCCGACAGTGATGAGCCGATCCAGAATATAAAATTAGAAAAGGAACAGAAGGAAAAATCTAcagtgaaaaagaaaacacaagCAACTGGGAAACTAAAGGACACTGCCCGTTCaaacatttcacacttgacacAATTAAAATTGACTTGGAAGAGCTACAATTGGTTGTGTACTTTTTGTGAGACTCAGTTTCCATCAGTTGATGAGCTCCGCACCCATGGCATGCAATACCACAGTGCTTGTAATCCATACCGATGTACGGATTGCAAGGTGAGAAAGTTACACTTGAACAATTTTATTCTACATGTGAAAAAACACAAGAGGTTCTTAAAATACTCTTGTTTCAAATGTTATAAGGTATTTGGTTCAGTAATTGCAGCAAATAAACACAAAGAAACCCATAAAACAACCAATATTATCTGTTTAGGGTGCAATACATGCTTTGATACCCAAGAAGAATTAGGAAATCATACTGCAACATATTTCAGAGGAACACGAGAAAGAAAACCACGTCCAATGGTACAATTGTCTGGTGATAATTTACAATGCCCAATATGTGAAAAAGTGTGCCCAACTAGAACAAGTTTGAGCACTCATTTATTAATTCACACTGACCGTAAGAAAGACCACACTTGTGAAATCTGTGGCAAATGTTTCTTTCAGAAAGGATCTTTGGCAGGACACATGCTTCAACATAGTGATTCAAGACCATACCAATGTGAAATTTGCACAGCTACATTCAAAAGCCCAAGACGTTTACGCCAGCACATGGCGATTCATGATGGTTTAAAACCGTTTTCTTGTGACCAGTGTGGTAAATGTTTCCGGATTAAACGTCAGCTAAATAATCATGCTATAATCCACACGGACTCCCTCCCTCATACATGCACCTATTGTGATAAAAGTTTCCGTTTCAAAGGGATACTGAATCAACATATCCGACAACACACTGGAGTTAAACCTTACTCTTGTGCGCTCTGTCAACGTGACTTCACAAATTGGTCAAATTACAACAAGCATATGAAACGCCGACATGCCACAGATATGTCGAAGACGAAACGGACTCCTGATGGCACATATCCCATTGATCCAGTTACTGGAGAGGTTATTATACCTGCTGAAGAAACAATAAGTGAATGGAGACAGAGAACATTGAAAAAAGATACTGTGACGGCAGCTACATGGAACTCATAA
Protein Sequence
MNNTANVYCRLCAELMPPNKLFDLQTDEEKCRDIIMKLTRFNVQVNFSDNILPKMVCYTCIMGLNRTFEFITAVEKAQSTLNDFILTRQIKLEKPGSDDELVVYDSSDSSDSDEPIQNIKLEKEQKEKSTVKKKTQATGKLKDTARSNISHLTQLKLTWKSYNWLCTFCETQFPSVDELRTHGMQYHSACNPYRCTDCKVRKLHLNNFILHVKKHKRFLKYSCFKCYKVFGSVIAANKHKETHKTTNIICLGCNTCFDTQEELGNHTATYFRGTRERKPRPMVQLSGDNLQCPICEKVCPTRTSLSTHLLIHTDRKKDHTCEICGKCFFQKGSLAGHMLQHSDSRPYQCEICTATFKSPRRLRQHMAIHDGLKPFSCDQCGKCFRIKRQLNNHAIIHTDSLPHTCTYCDKSFRFKGILNQHIRQHTGVKPYSCALCQRDFTNWSNYNKHMKRRHATDMSKTKRTPDGTYPIDPVTGEVIIPAEETISEWRQRTLKKDTVTAATWNS