Basic Information

Insect: Agrochola lota
Gene Symbol: THAP3
Assembly: GCA_947364205.1
Location: OX376248.1:7290876-7317990[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.21 16 6.6 1.2 1 23 357 379 357 379 0.92

2 11 0.002 0.15 13.1 1.2 1 23 386 409 386 409 0.93

3 11 0.29 22 6.2 0.2 1 23 413 435 413 435 0.92

4 11 0.11 8.6 7.5 0.9 1 23 440 463 440 463 0.97

5 11 0.003 0.23 12.5 0.3 1 23 467 490 467 490 0.96

6 11 5.5 4.2e+02 2.2 0.1 2 19 502 519 502 522 0.78

7 11 1.2 93 4.2 0.1 3 23 578 599 576 599 0.94

8 11 0.0041 0.31 12.0 0.6 2 20 615 633 614 636 0.92

9 11 3.1e-05 0.0023 18.7 3.1 1 23 642 664 642 664 0.99

10 11 0.00023 0.018 15.9 2.8 1 23 671 693 671 693 0.98

11 11 0.0027 0.21 12.6 3.9 1 23 699 722 699 722 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.21	16	6.6	1.2	1	23	357	379	357	379	0.92
2	11	0.002	0.15	13.1	1.2	1	23	386	409	386	409	0.93
3	11	0.29	22	6.2	0.2	1	23	413	435	413	435	0.92
4	11	0.11	8.6	7.5	0.9	1	23	440	463	440	463	0.97
5	11	0.003	0.23	12.5	0.3	1	23	467	490	467	490	0.96
6	11	5.5	4.2e+02	2.2	0.1	2	19	502	519	502	522	0.78
7	11	1.2	93	4.2	0.1	3	23	578	599	576	599	0.94
8	11	0.0041	0.31	12.0	0.6	2	20	615	633	614	636	0.92
9	11	3.1e-05	0.0023	18.7	3.1	1	23	642	664	642	664	0.99
10	11	0.00023	0.018	15.9	2.8	1	23	671	693	671	693	0.98
11	11	0.0027	0.21	12.6	3.9	1	23	699	722	699	722	0.89

Sequence Information

Coding Sequence: ATGAGGTGCAGTGTTCAGAATTGTTCTAATGACACGAGAACAACCAACAAAAGCCATGGAATCACATTTCATATGTTTCCGAAACAGCTGGATCTCCGCACTGCCTGGGTGGAGGCTCTCGGCATGTCTGACTGGGAGCCCAAAGACAGAAGCACCATATGCTCCGAGCACTTCCGAAGTGATGACATCTATGAGACCAAGGGTGGGCTGAGAAAGATAAAGTGTGGAGCAGTGCCTGTTGTGATGACACACTCAGCAGATGACCTTGAAGCACCAGCCTCATTGAGGGTGTGCCGAGTATGCCTTGTAATGGACAGAAAGATGTATCACATAAGAGAATTAAAATTGGATCAAATGTATGAGCAGATCACTGGATTGATGGCTAGTTCAGAAGAGCGTCTACCGCAGCGTGTGTGCTGGGAATGCGCCGCTCGTCTGAACTCGGCGTGTCGATTCAGAAACAAGGCTCTACGCAGCGATGCCTTGTTACATGATATGCTGCAGACCGACACTTATATAAAAATCCGCGACGTAAAATCGATAAACCGTAAACACAACCTCCTCACCTCTACCTTAATACATCAAATATACGAAAATGACGACTTCGACTTACGTATCAAAGACCTGTCTATCAAAACAGAGGAATTACCGGATACTTCCGAAATTATACCGATTATTACCGAAGAAATCGACGTCAAAAGCCTGGCACCCATTAACGAAATCGAAATAAAAGATGAAAGTAGTAACAATGAGATATTTTTTGAAGAATATGATCATTTCGATGATGAAGATGATAAGCTGTTAAGTGAAGTTTATGTGGAGAAAAAGGAGAAGCCTAAAGTTAAGAAAAAGAGGGAAAAGGTTGTTAAAAAACTTAAGCCAAAGAAGATTGAGGAAGAAGATGATCCCGACACTACTAGTGATAaGTACAAAAAAAACGACGTCAAACGCCGTCGAAACAACGAAGCATTCGACGAGTCGCTGTTTACAATCACTCCACTAACTTACGACCAACAGATAGAGGAGATTTTGAAACGCCAGGAGAGTTACAACTACACCAGCGCTCCTTATAAATGTACGATATGTTATCGAGGGTTCCAGATCAGGGATCGGTTCACCGCCCATTCTGTGAGGCATACTGAGCAATGCGGTGCTTACGAATGTTTTATCTGCAAAACTAGACTGAAAACTAGTCGAGCACTACGGAAACATCTAACGGCGCAGCATACCGAACAATATAGTTGTAAGGGGTGTCCGTTTGTCACTAGAAATAGAGGTGTAGCGAGGGAACACGAGAAGTGGCATGCCGGTACTAAATACCAGTGTCCGCACTGTGCTAGTGAATTTGATAAAATAACAACCTATATGGGTCATATTCGTATAAAACATGTTTCGGATTTCGTATGCGAGCTCTGTGGGTACACGTTTGTCAGTGAGAAGGGAATCGCTGTCCATAAAAAGAAGAAACATCGGATTGATAAAGCGTTGACATTAGAAGGTCCTTACTGTGAGCTGTGTGACGTGAAGTTCGTGTCGGAAGAGGCTCATGACAGACATCTGAAGTTATCGTCAAAACATAGCAGTGATCATGACCCTAACCGAATCCGGAATGACTCACAAAGCATGAATGCAGAACGCAATGGCCGCGTTATGAGACGAATAGAGAGGAGGCCGGTCATACACCCGCGCTTACCGAGCGACAGCGACCATGAACCGCACACACCCGTCAACTGTGAACAGTGCGGCATACAACTCCGCGACCTGCGGGTGTACGCGCAACACTTCCGTCGAGCTCACCCGGACAAGAACCGAACCAAGTACCCCGCGATGAAGACCCCCTGCATGTGTGAGCAGTGCGGGAAGATATTCCAGAGCATGGCCCTCCTCAAAGACCATATGTGGGTCCATACGGGCGAAAAACGCTTTAAATGTGACCGCTGTACTAAAAGCTTCACGCAGAAAACGAACCTCGTATTCCATATGAGAGTCCACAGCGCCACACGACCGAGCTACGAGTGTCCGCTGTGCGGGAAACACTTCGCGTTCTTCAATAACAGAAGACGTCATATGTTTATCCACACCGGTCTGAAGCCCTTCAAATGTGACAATTGTGGCAAATGCTTTACTACTGCTGGCGAACACAGGGCGCATGTCGAACATGTACATCTGAAGAAACCGTGGCCCAAGAGGGCGAGACAGCGGAACAGGGACTGGAAGTGCGATGACCCCAGTATTGAGGACTGA
Protein Sequence: MRCSVQNCSNDTRTTNKSHGITFHMFPKQLDLRTAWVEALGMSDWEPKDRSTICSEHFRSDDIYETKGGLRKIKCGAVPVVMTHSADDLEAPASLRVCRVCLVMDRKMYHIRELKLDQMYEQITGLMASSEERLPQRVCWECAARLNSACRFRNKALRSDALLHDMLQTDTYIKIRDVKSINRKHNLLTSTLIHQIYENDDFDLRIKDLSIKTEELPDTSEIIPIITEEIDVKSLAPINEIEIKDESSNNEIFFEEYDHFDDEDDKLLSEVYVEKKEKPKVKKKREKVVKKLKPKKIEEEDDPDTTSDKYKKNDVKRRRNNEAFDESLFTITPLTYDQQIEEILKRQESYNYTSAPYKCTICYRGFQIRDRFTAHSVRHTEQCGAYECFICKTRLKTSRALRKHLTAQHTEQYSCKGCPFVTRNRGVAREHEKWHAGTKYQCPHCASEFDKITTYMGHIRIKHVSDFVCELCGYTFVSEKGIAVHKKKKHRIDKALTLEGPYCELCDVKFVSEEAHDRHLKLSSKHSSDHDPNRIRNDSQSMNAERNGRVMRRIERRPVIHPRLPSDSDHEPHTPVNCEQCGIQLRDLRVYAQHFRRAHPDKNRTKYPAMKTPCMCEQCGKIFQSMALLKDHMWVHTGEKRFKCDRCTKSFTQKTNLVFHMRVHSATRPSYECPLCGKHFAFFNNRRRHMFIHTGLKPFKCDNCGKCFTTAGEHRAHVEHVHLKKPWPKRARQRNRDWKCDDPSIED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01441464;
90% Identity: iTF_00449181;
80% Identity: iTF_00037883;