Alot019886.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Agrochola lota
Gene Symbol
-
Assembly
GCA_947364205.1
Location
OX376247.1:6752382-6763641[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.86 65 4.7 0.2 1 21 408 428 408 431 0.87
2 10 0.018 1.4 10.0 0.4 2 23 457 479 456 479 0.95
3 10 0.014 1 10.4 3.9 2 23 502 523 501 523 0.96
4 10 0.00033 0.025 15.5 1.0 1 23 527 549 527 549 0.96
5 10 0.0013 0.1 13.6 1.3 1 23 554 577 554 577 0.96
6 10 0.026 2 9.5 0.5 2 23 585 607 585 607 0.91
7 10 0.0021 0.16 13.0 4.8 1 23 614 637 614 637 0.97
8 10 0.00039 0.03 15.3 2.4 1 23 643 665 643 665 0.97
9 10 8.3e-05 0.0063 17.4 3.4 1 23 671 693 671 693 0.98
10 10 0.00013 0.0096 16.8 2.8 1 23 699 722 699 722 0.98

Sequence Information

Coding Sequence
ATGTCGGTGGCAAAAACTGAGATAGAGACGTTTTTCGGTAGATGTAGGTGCTGTCTCTCCTATGGCTACTTAAAAAACATGTGGGCAGAACATCAATTTGAAGGAGAAGCAGAAATCTACGGCGAGATGCTTGTCCAATGTTTTGCACTGACTTGGGATCATTCGGACGACTCAATGGAGCAGGATCAGATTTGTGAGCAGTGCATCTGTCGATTGCGAGATGCTAGTGACTTTAAGAGAGTGGTCTTGGACTCGCAAGAGGAGTTGTTCCAACAGATAGAAGCTGAAAAAGAAATTAGCATCAAAGAAGAAAGACTAGATGAGGACTTCCTCATAGAGTACAATCATCCTGAGAGCGAGGAGAATGCGGACACTATGTACGCTGACACAGAATACACTATGGACCCCGCTGACACTGTGACGAGTGTCAAAGATGAGACGGAGTATGAGGAGGTTGAGTATTTGGAAGATGAAGATGCTGGTGGAGCAAAAGATGCTGTTGATACTGACTCGTCACAACCAACAGATCAGCCAAGACCAGCAAAACGGCAAAAGCAACCTCGTAAACAAAATACAGATGAAGAGGAAGCGCCGAAACGGAAATGGCCCAAAAAGCTGCCCAAATCAGAACGGCACAGAACTTACAAACAATACTCTGAGGTTGATCTACGCAAATGTCTGGAAGAAGTCAGGAACAATGTACTGACGCCTGCTGAAGCAGCTTTGAAGTATGATATACCGAAGAAGACTATTTCTGCCAAGATTAAAGTGGATCCTAATGATGTCCTGATTGACAATACAACGAAATCGAAATCGGAACGATCTAAAAAGAAACTGAGGACTATGCCCACCATGTTTAAAACCAAAGCATCATTTTTGGATGAAAAAACTAAAAAACTTATCGAGCTGAATAAATTAAAAGCAAAAAACTTATCAAAACCGGTCGTAACCACAGTAAAAGACAATGAAATGAATATTACCGAAACAAAAGTAATAGCTATAGAGATTAATATGGAGCCTAAGTCGGAAGAAATGGATGTCCCTGTAAATGCCGACCAAGTTCGAACGCGATACAAGACTATAGTCAACGACAAATTCAAGAAAGAAAATAAACAGCCCGAGAAATTTGAAATCAACGAAATGAATAAACATAAAGACAATATAAGGACTATATTACAAAATTCTAATGCGACCATCGTTAAAGGATTTTGGGGAACTGGTTATTCTTGTAATTTTTGCGACGAACAGAGAGAAATACCTTCAGAATTAAAGCTGCATAACTCAGAAGCTCATAGCAATGTAGGAGACGAAGCAATCAAAGTAAAATATGTATCTGATTTAGTTATAAGACTAGACATTACCGACCTCAAATGCAAACTATGCAACACAAGTATAAATTCTTTAGAAGAATTCACGGCACATTTAACTAAAATACATTCGAAATTGTTACACACAGATATTAATAACCACATAATTCCTTTCAAATTTAACACAGATAACTTACAATGCTGTATGTGTAAGAAAGAATTTAAGTATTTCAAGCTTCTTTCAGAGCACATGAGCGAACATTATAGGAACTACGAATGCTCGGTTTGCGACCGGGCGTTCATAAACAAGCAATCAATGCAAACCCACAGTTACAGACACAACAAAGGTGTCTTCAAATGCTCACACTGCCCGAAAGTTTTCGACTCTAGGCCGAAAAGAAGCGTGCATGAAAGAGTAGTACATGCTTTGTCTAACAAAACGAGAAAATGTTCGTTCTGTAGCGAAAGATTCGCGACGAAAGACTTGGTTCAAAGCCATGAGGTCAAAGCCCATGGGGTTAAACCAACAGTTTTCTCCTGCCAGGCTTGTAACAAGTCCTACCATAGCCAGAGTTCGCTGATGACCCATAGAAAGCGCTATCATTTAATGTTAAGACCTCACAAATGTTCGTATTGCGACATGGCATTTTTCTCCAAAATCGAGTTGCGTTCCCATACGGTTACTCATACAAAATCAAGGGATTTCAAGTGCGATATGTGCACGAAATCTTTTGGGACGCGGTGTAGTCTTAATCAACATGTTAGGGGACATTTAGATGATCGGAGGTTTAAATGTGATAGTTGTGAGCGAACGTTCGTCCATAGGACCGCTTGGAAAGTGCATATGAGGAGTAAACATAGTAGGATCGTTTAA
Protein Sequence
MSVAKTEIETFFGRCRCCLSYGYLKNMWAEHQFEGEAEIYGEMLVQCFALTWDHSDDSMEQDQICEQCICRLRDASDFKRVVLDSQEELFQQIEAEKEISIKEERLDEDFLIEYNHPESEENADTMYADTEYTMDPADTVTSVKDETEYEEVEYLEDEDAGGAKDAVDTDSSQPTDQPRPAKRQKQPRKQNTDEEEAPKRKWPKKLPKSERHRTYKQYSEVDLRKCLEEVRNNVLTPAEAALKYDIPKKTISAKIKVDPNDVLIDNTTKSKSERSKKKLRTMPTMFKTKASFLDEKTKKLIELNKLKAKNLSKPVVTTVKDNEMNITETKVIAIEINMEPKSEEMDVPVNADQVRTRYKTIVNDKFKKENKQPEKFEINEMNKHKDNIRTILQNSNATIVKGFWGTGYSCNFCDEQREIPSELKLHNSEAHSNVGDEAIKVKYVSDLVIRLDITDLKCKLCNTSINSLEEFTAHLTKIHSKLLHTDINNHIIPFKFNTDNLQCCMCKKEFKYFKLLSEHMSEHYRNYECSVCDRAFINKQSMQTHSYRHNKGVFKCSHCPKVFDSRPKRSVHERVVHALSNKTRKCSFCSERFATKDLVQSHEVKAHGVKPTVFSCQACNKSYHSQSSLMTHRKRYHLMLRPHKCSYCDMAFFSKIELRSHTVTHTKSRDFKCDMCTKSFGTRCSLNQHVRGHLDDRRFKCDSCERTFVHRTAWKVHMRSKHSRIV