Agen051601.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Agriphila geniculea
Gene Symbol
topi
Assembly
GCA_943789515.1
Location
CALSUL010000882.1:80554-86121[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 24 0.00088 0.18 14.1 0.0 2 21 142 161 141 162 0.94
2 24 0.00087 0.17 14.1 3.0 1 21 192 212 192 213 0.95
3 24 0.025 5.1 9.5 1.3 1 17 220 236 220 251 0.95
4 24 1.2e-05 0.0023 20.0 1.1 1 19 257 275 257 279 0.91
5 24 0.00034 0.069 15.4 1.8 1 23 286 308 286 308 0.98
6 24 0.0031 0.63 12.4 2.9 1 23 334 356 334 356 0.98
7 24 0.028 5.6 9.4 5.2 1 23 380 402 380 402 0.96
8 24 2.4e-05 0.0048 19.0 0.2 2 21 530 549 529 550 0.95
9 24 0.041 8.3 8.8 0.2 1 23 581 604 581 604 0.96
10 24 0.00016 0.032 16.4 0.1 1 19 609 627 609 629 0.97
11 24 1 2.1e+02 4.5 4.2 1 20 634 653 634 655 0.90
12 24 0.00058 0.12 14.7 0.2 1 23 668 691 668 691 0.95
13 24 0.00029 0.059 15.6 0.8 1 23 697 719 697 719 0.98
14 24 2.4 4.7e+02 3.3 0.4 1 23 753 776 753 776 0.87
15 24 0.00066 0.13 14.5 1.5 2 21 904 923 903 924 0.93
16 24 2.7 5.5e+02 3.1 0.3 3 23 931 952 931 952 0.96
17 24 0.043 8.7 8.8 1.5 1 23 957 980 957 980 0.94
18 24 1.4e-05 0.0029 19.7 0.4 2 23 986 1007 985 1007 0.96
19 24 1.1 2.2e+02 4.3 0.6 2 20 1011 1029 1011 1031 0.92
20 24 0.00031 0.063 15.5 0.3 1 23 1057 1080 1057 1080 0.95
21 24 0.00043 0.086 15.1 0.7 1 23 1086 1108 1086 1108 0.93
22 24 0.1 20 7.6 0.1 1 23 1114 1136 1114 1136 0.97
23 24 0.0067 1.3 11.3 0.2 1 23 1142 1165 1142 1165 0.94
24 24 0.00088 0.18 14.1 1.0 3 23 1173 1194 1171 1194 0.95

Sequence Information

Coding Sequence
ATGAATCAATCTATTGTGAAGCGAGAAAATAATGcggaaataaaattgtttttatttattcatacccAATGGAATGACCCATGGACGTTGTTCCAGATCGAGTCATCAACAATACTACCAAGAACTGTCTGCCCCCCGTGCGCTAAAGCCGCCATAGTGGCCGCGCCATTCATCCAACTCTGCAAGAACACGAATCAAAAGTGGACACAGATTACTGATTGTCTATTAAACTTGGACTATACTGTCTATGCTGTCTCTAAAGCTGCAAAAAGCACGTTCATTTGCTTCGATATAGATGAAGTCCAAATCGTTGAATGTAAAGACAAAGTTACTAATCTGAAGAAGGCGCATAAAGTcctcaaaaatgtttttcataaaCCGAACTACATAGTGCAAGATACCAAAGATATAGACTCAGATATAAAATGCCCTGAGTGTGGCAAAGCCTATACTAGTATCTACTTACTAAATGGACACTTAAAAGATATTGATAAAAAGATGTGTTATTATTGCAAAGAAATCATCGACATCAAAGAATTCGCTTCTCATGTTAGGAAACATGGTGCTGTACTTTTCACTTGTAATATATGCAAACATATGTTTAAATCCAAATCTAAATACCTCAGACATGTTAAGTTATGCAAGAGAAAAGGAAAGCATGTATGCGTTGATTGTGGACAAACTTTCGTCAGCGCTTCACAATTGGAGTACAGAATCAAGAACAGTTTAAGAGTTCACATACGGATCAATCATGGGGTAGGCTGGGAGTTCCAGTGTGAACAATGTGGAAAGAAATTTTCAAATCCCGCGCATTTGCGGGAACATGACAATATACACAATAAGGTGGCTGATAGATTCGTTTGCAGCATCTGTGGAACGAAGTATAGCACAAGGAGAGGTTACGAACGTCACAATAAAAAGCATTTTGATGAAAACGGCAAATTGACCACATATATGCCCACGCCTTATCCGAAAAAGAAAGACAATAACGACAATGGCTACATATGCAGCGTCTGTGGAAAGAAGTATTGCGCAAGGATGGCATACGAACGTCACTACAAAAAACATGTTGAAGAAAACGACAACTTGACCAAAACATACACGCCCATGCCTTATCCGAAAAATAAGGACGATAGACACGACTGCAACGTCTGTGGAACGAAGTGTAACTCAAGGATGGCTTACGAACGTCACTACAAAAAGCATTTTGAAGAAAACGGCAACTTGGCCGAAACATACACGCCCACACCTTATCCAAAAATTAAACGTACTTACAGACATTGCATTGTGGAGTTTGACGGGGGCTTGCCACAAGGACTGTGCACATTGTGCTCAGAGAGCGCCATCGCCGCTATAAACTTCCGACAGCTTTGCAAGGAGTCCAACAACCAGTGGAAGCGAGTCACCTCCATTGTGGACAATATTGCTCCCCCGTCGAAAGAAGATGCCACCTATTACATATTCTACAATACCGATGATCTCTCAAATCCGACAGTGAAAGTGGTAAAGAAGCGGCCCGCTTCATTCGAACCTCTCTTATTAGTAGGAATGAAACCAGAGAAAATGCCTCGCCTGTTATCTTCAATGCAATGTCCTGATTGCGGCAAACAATTTCCTAGTCCCATTCATTTAAACTCCCATTTGAAAAACTCAGTGAAAAGAGTGTGTGACTTATGTGGTCTCTTTTTTGACAAGCCAAAGTTTCCACAACACTTGCATAAGGCTCACAACAAGATTGCGTATCCCTGCAACTCCTGTCATCAAATATTTGAGGACGAGATTTCTTTGGATTTACACTTGCTAAAAGCGCACGGAAACAATTCTTATGAATGTAAAGTGTGCGGAAAAGGGTTCACCAATGAAAGAGGTCTTACAGCACATTCGTACTGCCACTCACTATTCCTCTGCACATCATGTGGCCGAACTTTCGAGAACCGGAATTGTTACATGTACCATCGCCACCAATGTCAGCCAGAAACTCCTAGTTCAGAAACGAACGAATACATATGTGACGTTTGTGGCAATTCCTATACTAAAAAGCCTTCCTTGAGGATTCATATAATCCAGAAGCATTTAAACGTCCTACCGTATGTTTGCGCAACTTGTGGTAAACGCACCTCCACCATAGCACATTTACGATCGCACGAGAAAGTGCATACACTTCATAGAAGTACGTTTAATTGTCATTGCGGAGCTGTAATGAAGACAGAATTAGGTTATCAGTTGCATTTACGTAAGCATACTGGAGAAAAGCCATATGAATGTGATGAGTGCGGCGATAAGTTTCTGTCAGCTTCTAGACGACTGGATCATATTAAACGTAGGCATAGGCCTACTAAAGATATGCCGCATGGTTGCAAAGAGTGTTCCGCGCGTTTCATTGAAGAAGAGAAATTCTGCCCGAAAGGAGCATGCGTGACATGCGCCTCAGCTGCTATGGCTGCACAAGAATTCCGAGTATTCGTGCGCAACTCACAAAGCATGTGGCACAAAGCAATAAATGCTCTCAGTGAAGTGCCGAAATCCTACGGGCCTTCAGTCAGATCTCTATGCTCATTTGTTAAACCAGACAACTTTCAAACCCACACAGTTAAAGACTACACTGGCGGTGACTCAAAACAAATACTGAACAGATTAAGAACCCGCCTAACTAAAAGGAAGGCTGAAATCGAAAAGAAAGCCAGGACTCCGCGGTCGGGACCGGCCTGCAACTGTCCCGACTGTGGCAAAAACTTTTTCAGCCCGTACTTTTTGCGTTTGCACTTAAAAAATAGTGGATTTAAAGAAGGTTGCTTGCATTGCGGTGCGGTTTTGGCAAGGGGCAATGAAATGAAGGAGCACCTTTCTAAAGTTCACGGCGAAACGTTGTTCCTTTGCAAGAAATGTCCGATGTTGTTCACGAGCGACATTAAGCTAAAGAAGCATAGTAGAAAAGCTCATAAACCTGGCGCTTGGACTTGTAATGACTGTGGAAGATCTTTTCCGAGTAAGACTTCGCTAGAGATGCACTCGCAAATGCACACAGTCAGGACATGCAGGGCTTGTGGTGCGCAGTTCACGAACCGTGGTTGTTACAGGGAGCACAGGGCTCTGTGCGAACCAAACGCGCGTCCAGACAGACATTCCCTTCCGCGCAACAAAAGATCGAACATTCGAGATCCCGCAACTTTCACGTGCGATTACTGTGGCAAAACATACCTTTCGCGACCCCaacttaaaaaccatataatTTGGATACATATGGACGTTAGGCCACACCAATGTCAGTGGTGTGGAAAAAGATTTTACACCCCTTCCCGATTAGCGGAGCATTCGGTCGTGCATACGCGGGAAAGGAATTTTGAATGTGACATTTGTGGTGCCAAATTGGTGTCTAAAATGGCGGCTGTTTATCACAGGCGAAGGCATACTGGAGAAAAGCCTTATGAGTGTGAAGATTGCGGCGAAGGTTTCATATCGTCTTCAAGAAGGTCGGAACACGCGAAAAGGAGACATGGGAGAGGACAAAAAATACATTGTTTGCAGTGTCCATctacttttgttagaaaatatgAGCTTTTAAAACACATGGAAAAGGCACATAGGACTCAAGGGCAGAACATAGGAGCCATAAATAAAGACCCGGTAATAGAAAGCTACGAAATTGTAGATATATAA
Protein Sequence
MNQSIVKRENNAEIKLFLFIHTQWNDPWTLFQIESSTILPRTVCPPCAKAAIVAAPFIQLCKNTNQKWTQITDCLLNLDYTVYAVSKAAKSTFICFDIDEVQIVECKDKVTNLKKAHKVLKNVFHKPNYIVQDTKDIDSDIKCPECGKAYTSIYLLNGHLKDIDKKMCYYCKEIIDIKEFASHVRKHGAVLFTCNICKHMFKSKSKYLRHVKLCKRKGKHVCVDCGQTFVSASQLEYRIKNSLRVHIRINHGVGWEFQCEQCGKKFSNPAHLREHDNIHNKVADRFVCSICGTKYSTRRGYERHNKKHFDENGKLTTYMPTPYPKKKDNNDNGYICSVCGKKYCARMAYERHYKKHVEENDNLTKTYTPMPYPKNKDDRHDCNVCGTKCNSRMAYERHYKKHFEENGNLAETYTPTPYPKIKRTYRHCIVEFDGGLPQGLCTLCSESAIAAINFRQLCKESNNQWKRVTSIVDNIAPPSKEDATYYIFYNTDDLSNPTVKVVKKRPASFEPLLLVGMKPEKMPRLLSSMQCPDCGKQFPSPIHLNSHLKNSVKRVCDLCGLFFDKPKFPQHLHKAHNKIAYPCNSCHQIFEDEISLDLHLLKAHGNNSYECKVCGKGFTNERGLTAHSYCHSLFLCTSCGRTFENRNCYMYHRHQCQPETPSSETNEYICDVCGNSYTKKPSLRIHIIQKHLNVLPYVCATCGKRTSTIAHLRSHEKVHTLHRSTFNCHCGAVMKTELGYQLHLRKHTGEKPYECDECGDKFLSASRRLDHIKRRHRPTKDMPHGCKECSARFIEEEKFCPKGACVTCASAAMAAQEFRVFVRNSQSMWHKAINALSEVPKSYGPSVRSLCSFVKPDNFQTHTVKDYTGGDSKQILNRLRTRLTKRKAEIEKKARTPRSGPACNCPDCGKNFFSPYFLRLHLKNSGFKEGCLHCGAVLARGNEMKEHLSKVHGETLFLCKKCPMLFTSDIKLKKHSRKAHKPGAWTCNDCGRSFPSKTSLEMHSQMHTVRTCRACGAQFTNRGCYREHRALCEPNARPDRHSLPRNKRSNIRDPATFTCDYCGKTYLSRPQLKNHIIWIHMDVRPHQCQWCGKRFYTPSRLAEHSVVHTRERNFECDICGAKLVSKMAAVYHRRRHTGEKPYECEDCGEGFISSSRRSEHAKRRHGRGQKIHCLQCPSTFVRKYELLKHMEKAHRTQGQNIGAINKDPVIESYEIVDI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-