Basic Information

Gene Symbol
-
Assembly
GCA_932301435.1
Location
CAKOAR010000077.1:89089-94967[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.0041 0.24 12.3 0.8 2 23 226 248 225 248 0.94
2 10 0.0011 0.066 14.0 0.6 2 23 273 295 272 295 0.94
3 10 2.6 1.5e+02 3.5 4.1 2 21 319 338 318 340 0.94
4 10 5.3e-05 0.0032 18.2 1.9 1 23 344 366 344 366 0.97
5 10 0.48 29 5.7 1.0 1 13 371 383 371 384 0.91
6 10 6.9e-05 0.0041 17.8 1.8 3 23 404 425 402 425 0.96
7 10 4.5e-07 2.7e-05 24.7 1.4 1 23 432 455 432 455 0.98
8 10 0.001 0.061 14.1 0.6 1 23 461 483 461 483 0.96
9 10 1.2e-06 7e-05 23.4 3.3 1 23 489 511 489 511 0.99
10 10 7.8e-05 0.0046 17.7 1.4 1 23 517 540 517 540 0.97

Sequence Information

Coding Sequence
ATGTCTTCCCTTCAGCTATGTCGTTGCTGCATGACACGGCCACCCGATAAGAACTTAAAAACCGAATATACCAGACTCGGAGTAGCTGAAGTTTACGCCGATATGCTCAAAGAATGCTTCGAAATAAACCTAGCAGCAGGGAGCGAGAGCTCAGCTGGTATCTGCGAAGTGTGCGTGACTCGACTGTGTGATGCGGCAGACTTCAAGAAGCAGGTGCAGCTCTGCCAGAAGGCCTGCAATGAGATCCTTACACAAGGAGTCAAAGATGAAGCAGTGCCCAAGGTGAAAGAAGAACTTGCCGACTATGATGACAACGGCATCTATTTTCTTGACCTGAAGGAAGAGCTGTCCTCGTACGAAGACTTGCACGAAGATGCCGAAGACGACAAGAAGCTGGCAGAGCTGCTGGGGCTTCGCCACCTGGGTGCCACCACCGTGCGACGAAAGACTTCAAGGAAAAAGGACAAGCTGGCGAGAACCGACAAAAAGTTAAAGAAGAGATCGTCCGAGGCCCTCAAGATCTCGTTCGCAACGCTCTCCAAGTTAGACAAGATCTACCCGCTGAAGCAAGGCAGCTTCCGCACCAGCGACGCCGTCAAACACAAAACCAACATGGACAACCTCATGAAGAACtccaactgcaccccctttgccaacaaaaccctcgccggaatcacctgcgtcttctgcaagcaaacctaccaaaacccacaagaactccgcacgcatatgcaagataaacacaaagacgacagcatactcgacccctcgaaagacaaaagcaatctctcctacaaactagatatttccgacctaaaatgcacgatttgcagtaaaaactttgatgtaataactaatttgaaaagtcatttgagcaacgaacacgatgtgaaattctatccggacgtccacgattatatcttggagtttaaactgacagatgcagagatgctgaagtgtgcgttatgtcactccacatatgaaacgttcaaaatgttgttgcaacacatgaattgccattacagaaatttcatctgcgaagcttgcgatatgggcttcataaataaacacaagctgaaaaatcatcaacgtacacacgaggtgggcaacttcaaatgcgcgttctgcgataaagaattcccgaccagagtccgaaagatgtgccatgaaaaatatacccacaacacttcagcgagatatacaacaaactgcccgcagtgcgagaaatcattcaccagctactatcaaaggaatcgtcatatgttcaccgaacataacaccgttgcagccacttacaaatgcaatatatgtgataaatcattcatactaaaatcaaaacttacatctcatataaaaaaagtacacctaatggaacggaatcacatatgcacggtttgcggtcaagggttcttcataaagcaatcgttagaagagcacatgatcaagcataacggggaacgtgttttcaaatgcacggtctgtcataaagcgtatgccaggaagaagactttgagagaacatatgcggatacataataatgataggagatttaagtgcggggtttgcggtttggcgtttgtgcagaagtgtagcatgaaaagtcatatgttgtccaaccacggGATCACGTTGGCTGAGTATGAGACTTCACAAGCTGATGAGACGAGGTCTGAAGTGAGGATGGAATGTGAAAGAGTGCAATAA
Protein Sequence
MSSLQLCRCCMTRPPDKNLKTEYTRLGVAEVYADMLKECFEINLAAGSESSAGICEVCVTRLCDAADFKKQVQLCQKACNEILTQGVKDEAVPKVKEELADYDDNGIYFLDLKEELSSYEDLHEDAEDDKKLAELLGLRHLGATTVRRKTSRKKDKLARTDKKLKKRSSEALKISFATLSKLDKIYPLKQGSFRTSDAVKHKTNMDNLMKNSNCTPFANKTLAGITCVFCKQTYQNPQELRTHMQDKHKDDSILDPSKDKSNLSYKLDISDLKCTICSKNFDVITNLKSHLSNEHDVKFYPDVHDYILEFKLTDAEMLKCALCHSTYETFKMLLQHMNCHYRNFICEACDMGFINKHKLKNHQRTHEVGNFKCAFCDKEFPTRVRKMCHEKYTHNTSARYTTNCPQCEKSFTSYYQRNRHMFTEHNTVAATYKCNICDKSFILKSKLTSHIKKVHLMERNHICTVCGQGFFIKQSLEEHMIKHNGERVFKCTVCHKAYARKKTLREHMRIHNNDRRFKCGVCGLAFVQKCSMKSHMLSNHGITLAEYETSQADETRSEVRMECERVQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00935982;
90% Identity
iTF_00033225;
80% Identity
-