Basic Information

Insect: Agriopis leucophaearia
Gene Symbol: ZFX
Assembly: GCA_949125355.1
Location: OX421290.1:7484668-7507243[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.26 19 6.6 2.2 1 23 287 310 287 310 0.97

2 11 0.0011 0.08 14.1 1.0 1 23 317 339 317 339 0.99

3 11 0.024 1.8 9.9 1.7 1 23 343 366 343 366 0.95

4 11 4 2.9e+02 2.9 1.2 1 23 373 395 373 395 0.77

5 11 2.8e-06 0.00021 22.2 1.0 2 23 400 422 399 422 0.96

6 11 0.00033 0.024 15.7 0.9 1 20 428 447 428 450 0.93

7 11 0.016 1.1 10.5 1.9 2 21 461 480 460 485 0.93

8 11 4.4e-05 0.0032 18.5 1.5 1 23 493 516 493 516 0.94

9 11 2e-05 0.0015 19.5 0.6 1 23 521 544 521 544 0.98

10 11 5.1e-07 3.7e-05 24.6 3.1 2 23 552 573 551 573 0.97

11 11 1.3e-05 0.00092 20.2 1.4 1 23 579 602 579 602 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.26	19	6.6	2.2	1	23	287	310	287	310	0.97
2	11	0.0011	0.08	14.1	1.0	1	23	317	339	317	339	0.99
3	11	0.024	1.8	9.9	1.7	1	23	343	366	343	366	0.95
4	11	4	2.9e+02	2.9	1.2	1	23	373	395	373	395	0.77
5	11	2.8e-06	0.00021	22.2	1.0	2	23	400	422	399	422	0.96
6	11	0.00033	0.024	15.7	0.9	1	20	428	447	428	450	0.93
7	11	0.016	1.1	10.5	1.9	2	21	461	480	460	485	0.93
8	11	4.4e-05	0.0032	18.5	1.5	1	23	493	516	493	516	0.94
9	11	2e-05	0.0015	19.5	0.6	1	23	521	544	521	544	0.98
10	11	5.1e-07	3.7e-05	24.6	3.1	2	23	552	573	551	573	0.97
11	11	1.3e-05	0.00092	20.2	1.4	1	23	579	602	579	602	0.95

Sequence Information

Coding Sequence: ATGGACGCAGTAAAAGATGGATTTTCATTGCAAATCCTGTGCAATGCTTGTCTGTGCATCGGGAGAACTCTATACCAGGTCAAAGACGAGAAATTGAAGCAGTACTACCTCGGGGCTCTGAGTGAAATTCCACTGTACAACATGCCCGCAGTGTCTCCGATGGTCTGTTTGGACTGCCGAGCGCTGCTCCGAAATTCGTACGAGTTTAGAGAGCAAGTGAAAGACTCGCACCGTATACTTATGACGTACACCAGTGAGAATCTGAATGAATGTCTGCTCACGGACGTGTCGCGGCCGCCGCGACTGAAGATACATACCAACGACCACGTAAACATACATCCAGAGACATCACACATCAGAATAGATAAATGtacacataaaaaacacaagAAGTTCAAGCGTTCCTGTCAGATTGAAAGGAGTCAGgcaAGTGGTTTTCAATGCGAGACAATGCATAGAATATCTCCCAGATCCAGTCCACATTCCGATGTGCCCACAAGCTGCACACAAGAAGTGTATGTCAAGGAGGAATTGAAAATTGAATTCTACGATAGCGACCGAGaTGATTTTGATACACCGTTAGTAGATTTAAAACAAGTCGACACCCTGGCCGATGCTGATACAGAaaaaagttccactatccaAGATGAGAAAAGTAGTtatttcattgaacaaataaagaaaaataaaataaaaagaagtaaGAAAATTGGAAAGATTAAAAGCAAGAAGAAAGTTAAGAAGAATGAAGAAAAAATCGTAGAGGTACCAAGTATAGTAACTGTACATATGACTTACGAAGAAATGATGGAGGAGAGACGGAGAGAAAGTAACAGAGACGGCTATATGAACGCAGAGTTTAAATGTGAGACCTGTATATTAGGATTCAACTATATGAAGtcatataaaaaacatttactgACCAGACATTCACCGGGTATTGGCAAATACACATGTCCAATATGCAAGACTGTTTTAACTACGGTGGAATCGTTTTCTACGCACTATAAAAGGCATATGAAAAGATACGAATGCAGTATATGTCAGAAGCGAACGATGGACCTGAAGTCGATGCAGCAGCATTACTACTCCACGCACGATATATCTCTCAAGCAGTACAAGTGTGGGGACTGCGGGAACATTTCCAACTCCGTGGACTCACATCGATACCACACGGACACACACAAGTCCCGACTCCAGTGTCCGGACTGTGACAAGACCTTCCGGCACCGAGGGGGGCTCCTCAACCATAAACTCACAGTGCACGAGGCGCGCAACAAGTTTCCCTGTACTTACTGCAACAAGGTGTTCCGATGGAAAAACAGTCTCAAGCGACATCTGCCCATCCACGACGACAAGACTAAACCTGAATCAGTGTGGCAGTGTTGTCTGTGTCGCGTCAGTTTCGCGTCGCTGGCCTCCTACAAGCGACACATGAAGAACAGCTTGCGACACGTCACCAAGGAACATTTGAGGTTCATATGCGACCATTGCGACCGTCGGTTCGCTGATAAGACCAAGCTCCGTGACCACATTGAGGAGAAACATCTGCACAAGACATACCAATGTACAATATGTCTAAAGACTTTTATGAACCGCGTGAATCTGGACCAGCATATCCGTAACGTCCACAAAGGGAGACCTAACAACAAGATGTGTCACCACTGCGGTAAAGGATTCCCTACGAAAGCCCAGCTGGAGTCGCACATCCGCACACATACTGGGGAGAGACCATTCATCTGCGAGTTCTGTCCCACCACCTTCTCCCAGCAGTCCAACTTGTACAAACACAACCGACAGgtacatttaaatatgaaaTCGAAGCGTTACCCGACAGTTAAGAAGAGGAAAGACGACCAACTGCAAATGGCAATGGAACCATCAGACATACCGATCGATTACCCTGTAGATATAGGATTTGCTATGTAA
Protein Sequence: MDAVKDGFSLQILCNACLCIGRTLYQVKDEKLKQYYLGALSEIPLYNMPAVSPMVCLDCRALLRNSYEFREQVKDSHRILMTYTSENLNECLLTDVSRPPRLKIHTNDHVNIHPETSHIRIDKCTHKKHKKFKRSCQIERSQASGFQCETMHRISPRSSPHSDVPTSCTQEVYVKEELKIEFYDSDRDDFDTPLVDLKQVDTLADADTEKSSTIQDEKSSYFIEQIKKNKIKRSKKIGKIKSKKKVKKNEEKIVEVPSIVTVHMTYEEMMEERRRESNRDGYMNAEFKCETCILGFNYMKSYKKHLLTRHSPGIGKYTCPICKTVLTTVESFSTHYKRHMKRYECSICQKRTMDLKSMQQHYYSTHDISLKQYKCGDCGNISNSVDSHRYHTDTHKSRLQCPDCDKTFRHRGGLLNHKLTVHEARNKFPCTYCNKVFRWKNSLKRHLPIHDDKTKPESVWQCCLCRVSFASLASYKRHMKNSLRHVTKEHLRFICDHCDRRFADKTKLRDHIEEKHLHKTYQCTICLKTFMNRVNLDQHIRNVHKGRPNNKMCHHCGKGFPTKAQLESHIRTHTGERPFICEFCPTTFSQQSNLYKHNRQVHLNMKSKRYPTVKKRKDDQLQMAMEPSDIPIDYPVDIGFAM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00034060; iTF_00044780;
90% Identity: iTF_00034060;
80% Identity: -