Basic Information

Insect
Agrilus mali
Gene Symbol
Zfp42
Assembly
GCA_029378335.1
Location
CM055659.1:24574217-24576961[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 22 0.0038 0.37 12.3 1.3 2 23 48 69 47 69 0.96
2 22 0.38 37 6.1 0.7 1 23 90 112 90 112 0.94
3 22 0.028 2.8 9.6 1.4 1 23 116 138 116 138 0.97
4 22 0.17 17 7.1 1.8 1 23 144 168 144 168 0.97
5 22 0.00042 0.041 15.4 2.7 1 23 174 196 174 196 0.97
6 22 0.0036 0.35 12.4 0.9 1 23 202 225 202 225 0.95
7 22 0.015 1.5 10.5 1.7 2 23 237 258 236 258 0.97
8 22 2.2e-06 0.00021 22.6 1.1 3 23 272 292 270 292 0.96
9 22 3.9e-06 0.00038 21.7 1.1 1 23 298 320 298 320 0.98
10 22 1.5e-05 0.0015 19.9 0.3 1 23 326 348 326 348 0.97
11 22 0.71 69 5.2 0.4 1 13 354 366 354 367 0.90
12 22 0.28 27 6.5 1.7 2 23 398 419 397 419 0.96
13 22 1.3 1.3e+02 4.4 1.8 1 23 440 462 440 462 0.92
14 22 0.015 1.4 10.5 0.3 1 23 466 488 466 488 0.98
15 22 0.077 7.5 8.2 0.2 1 23 494 518 494 518 0.97
16 22 0.0029 0.28 12.7 2.6 1 19 524 542 524 546 0.91
17 22 0.00045 0.044 15.3 2.4 1 23 552 575 552 575 0.97
18 22 0.0002 0.02 16.3 3.4 2 23 587 608 586 608 0.98
19 22 0.00041 0.04 15.4 0.9 3 23 623 643 621 643 0.96
20 22 1.2e-05 0.0012 20.2 0.7 1 23 649 671 649 671 0.97
21 22 5.9e-06 0.00058 21.2 0.5 1 23 677 699 677 699 0.98
22 22 5.4e-05 0.0053 18.2 0.2 1 21 705 725 705 726 0.96

Sequence Information

Coding Sequence
atgccCTGGTCTAAGGTTCACATCCTaaaaatagAGTTTAAACATGAAAGTTCAGAATCTTCAGATGACCTTAACAACGACGAATGGTCACCGTTCAACAGCTACAAAAAAAGATCAACCCGAAAAGTTAAAAGGAAATGGTCATGCGCAAGATGCAAAGAAGACTTCGACACAAGCACAAAACTTCGCGAACACAGAAAGACCCATCGGAGAGACAGATATGACGACACCCAGTACAGCTACACTTTTGACCCTGCTAAAGACATATACAGTTGTATAACGTGCGACATGGAATGTCCATCAAAAAAGGAGATTGAAAAGCACGTTCTTACTCACAAAGACCATTTTTCATGTGAACAGTGCGATTTGTTCTTCGATGAACCTTACAAATACGCCACTCACGTTCACATGCACAGTAAGGACAGTTTATTTCGATGTCCTCTCTGTGATGCGTACAAAACCCCCAATCGTACTTGTCTCCTCACTCACATCAACACTTTCCATCTTCATCGATTTATATACAGGTGTTCGACATGTGGCAAAGGTTTCAACGATTGCGTCCAGTTCAAAGAGCACAATAACATTCACAAAGGTCTCAAACCGTTCGAGTGCGTCGTGTGCGGCAAAGGGTTTCCCTTCTCCCTCTACCTGCACACGCATCAGGTTCGCAACCACAGGGCGACCATAGACGGGGTGCTCGGGATCAACCAGTGCTACGTCTGCATGAAAAACTACGTCAACACCAGAACGTTACAGAAGCATATGCTTAAACACAGCaccaaagaaaagaaaaactacGAAAAGAATCATCTGTGTGACATATGCGGAAAAGGGTTCGCCAGAAAGGATAAGCTAAAGATACACTATAGGGTTCATACAGGAATTAAACCCTACAGTTGTTCGTATTGTCCTAAGAGTTTTACTAAAAGGGATTATCTGGTGATGCACGAGAGGGTTCACAGTGGTGAGAAACCCTACGCGTGCGAATATTGTGGAAAATGTTTCAATCAAGGTGCCCCCTTGAGGGTTCATATACGGGGTCACACAGGAGAACGCCCATACGTCTGTCACATATGTAACTCTGGATTTACATCGCGCGAGCCGGAATCAAGTGAAGATTCTACTGCTGAACAGTGGACCCCAAGAACGCGACGGTATAGAAACAGgacaaaaaggaaaattaataGTTGGATGTGCACCAAATGCAACATCCAGTTAGATACGAGAATAAAGTTTCGCGAACATAAAAAAACTCACAAGCAACAACCTTTAGACGACAGTCACTACAGTTACACTTTTGACACCACAAAAGACGTTTATAACTGCATCACATGCGACTACGAATGTTATTCGAAAAACGAAATGAAACAACACGTTTCTGTGCACAAGGATCATTTTACGTGCTCAACATGTAAAGTACAGTTCGAGGAACCTTACGAATACGCCACACACGTAAACATTCACACAGGAAACGTCGGTTTTAAGTGCCCTTTATGTGACGTCTACCAAACACCAAGCCGCAATTCCCTCCTTATTCACATTAACACCTACCACTTAAAAAGATATTACTACAGATGTACCACATGCGGCAAGGGTTTTAACGATTGCGTCCAGTTCAAAGAGCACGACAATGTGCACCAAGGTTTGCGTCCATTCAAGTGCGTTGTGTGCGGTAAAGACTTTGTTTTCTCCACGTATCTTCATACTCATCAAATACGTAATCACAAAGTCACCATCGACGGAATTATCGGTACAAATCAGTGTAACATCTGCCTTAAACGTTGTGCGAACTTGAGCACTTTACAAAGGCACATTAAGAAACACGAGAACCAAGTCAAAGTGAAGAAAGGCGAAAAGAGACATTTGTGTGACATATGCGGCAAAAGGTACGACGTTAAAGCGAAATTAGATATTCATTATAGGACGCATACAGGAGAAAAACCTTTTGCATGTTCTTACTGTCCTAAAAGCTTTACCAAACGCGAATATTTAGTAATGCACGAAAGGGTCCACAGTGGTGAGAAACCATACGCTTGTGAATATTGTGGAAAGTGCTTTAATCAGGGTGCACCTTTAAGGGTGCATATACGAAGTCACACTGGAGAACGTCCCTATGTTTGTCATATTTGTAATACCGGGTTCACGTCCCGAGGGGCTTTGAACATCCAccttaaaaattgtaacggaAAAGGAAAATGA
Protein Sequence
MPWSKVHILKIEFKHESSESSDDLNNDEWSPFNSYKKRSTRKVKRKWSCARCKEDFDTSTKLREHRKTHRRDRYDDTQYSYTFDPAKDIYSCITCDMECPSKKEIEKHVLTHKDHFSCEQCDLFFDEPYKYATHVHMHSKDSLFRCPLCDAYKTPNRTCLLTHINTFHLHRFIYRCSTCGKGFNDCVQFKEHNNIHKGLKPFECVVCGKGFPFSLYLHTHQVRNHRATIDGVLGINQCYVCMKNYVNTRTLQKHMLKHSTKEKKNYEKNHLCDICGKGFARKDKLKIHYRVHTGIKPYSCSYCPKSFTKRDYLVMHERVHSGEKPYACEYCGKCFNQGAPLRVHIRGHTGERPYVCHICNSGFTSREPESSEDSTAEQWTPRTRRYRNRTKRKINSWMCTKCNIQLDTRIKFREHKKTHKQQPLDDSHYSYTFDTTKDVYNCITCDYECYSKNEMKQHVSVHKDHFTCSTCKVQFEEPYEYATHVNIHTGNVGFKCPLCDVYQTPSRNSLLIHINTYHLKRYYYRCTTCGKGFNDCVQFKEHDNVHQGLRPFKCVVCGKDFVFSTYLHTHQIRNHKVTIDGIIGTNQCNICLKRCANLSTLQRHIKKHENQVKVKKGEKRHLCDICGKRYDVKAKLDIHYRTHTGEKPFACSYCPKSFTKREYLVMHERVHSGEKPYACEYCGKCFNQGAPLRVHIRSHTGERPYVCHICNTGFTSRGALNIHLKNCNGKGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
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80% Identity
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