Basic Information

Insect: Agrilus mali
Gene Symbol: ZEB2
Assembly: GCA_029378335.1
Location: CM055659.1:24647291-24652853[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 28 4.9e-05 0.0047 18.3 1.2 2 23 121 142 120 142 0.94

2 28 0.061 6 8.5 1.7 1 23 146 168 146 168 0.98

3 28 1.9 1.8e+02 3.9 0.1 1 23 174 197 174 197 0.87

4 28 0.061 5.9 8.6 1.4 1 23 204 226 204 226 0.93

5 28 0.002 0.19 13.2 4.9 1 23 232 255 232 255 0.98

6 28 0.0057 0.56 11.8 4.5 1 23 264 286 264 286 0.97

7 28 0.00078 0.076 14.5 1.0 3 23 293 313 292 313 0.98

8 28 0.00057 0.056 14.9 1.9 1 23 319 341 319 341 0.96

9 28 0.00012 0.012 17.1 0.4 3 23 349 369 347 369 0.97

10 28 0.00011 0.011 17.2 0.2 1 22 375 396 375 396 0.96

11 28 0.007 0.68 11.5 0.8 2 21 465 484 464 485 0.94

12 28 0.0079 0.78 11.3 0.2 3 23 542 563 541 563 0.90

13 28 0.0093 0.91 11.1 0.2 1 23 567 589 567 589 0.98

14 28 4.8 4.7e+02 2.6 1.1 1 23 595 618 595 618 0.74

15 28 0.00064 0.063 14.8 1.8 1 23 635 658 635 658 0.97

16 28 0.0001 0.01 17.3 2.8 2 23 667 689 666 689 0.96

17 28 8e-05 0.0078 17.6 2.0 2 23 695 716 694 716 0.96

18 28 8.5e-06 0.00083 20.7 1.4 1 23 722 744 722 744 0.98

19 28 8.4e-05 0.0082 17.6 3.3 1 23 750 772 750 772 0.98

20 28 1.5e-05 0.0014 19.9 0.3 1 22 778 799 778 799 0.97

21 28 1.5 1.5e+02 4.2 2.8 1 21 895 915 895 916 0.92

22 28 0.0016 0.15 13.6 6.1 1 23 1057 1079 1057 1079 0.96

23 28 0.00027 0.027 15.9 1.1 1 23 1085 1108 1085 1108 0.93

24 28 0.86 84 4.9 0.1 2 23 1117 1139 1116 1139 0.88

25 28 0.00029 0.028 15.9 0.1 1 23 1144 1166 1144 1166 0.97

26 28 6.7e-06 0.00065 21.0 1.1 1 23 1172 1194 1172 1194 0.98

27 28 4.7e-06 0.00046 21.5 1.8 1 23 1200 1222 1200 1222 0.97

28 28 0.0046 0.45 12.1 1.0 1 21 1228 1248 1228 1249 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	28	4.9e-05	0.0047	18.3	1.2	2	23	121	142	120	142	0.94
2	28	0.061	6	8.5	1.7	1	23	146	168	146	168	0.98
3	28	1.9	1.8e+02	3.9	0.1	1	23	174	197	174	197	0.87
4	28	0.061	5.9	8.6	1.4	1	23	204	226	204	226	0.93
5	28	0.002	0.19	13.2	4.9	1	23	232	255	232	255	0.98
6	28	0.0057	0.56	11.8	4.5	1	23	264	286	264	286	0.97
7	28	0.00078	0.076	14.5	1.0	3	23	293	313	292	313	0.98
8	28	0.00057	0.056	14.9	1.9	1	23	319	341	319	341	0.96
9	28	0.00012	0.012	17.1	0.4	3	23	349	369	347	369	0.97
10	28	0.00011	0.011	17.2	0.2	1	22	375	396	375	396	0.96
11	28	0.007	0.68	11.5	0.8	2	21	465	484	464	485	0.94
12	28	0.0079	0.78	11.3	0.2	3	23	542	563	541	563	0.90
13	28	0.0093	0.91	11.1	0.2	1	23	567	589	567	589	0.98
14	28	4.8	4.7e+02	2.6	1.1	1	23	595	618	595	618	0.74
15	28	0.00064	0.063	14.8	1.8	1	23	635	658	635	658	0.97
16	28	0.0001	0.01	17.3	2.8	2	23	667	689	666	689	0.96
17	28	8e-05	0.0078	17.6	2.0	2	23	695	716	694	716	0.96
18	28	8.5e-06	0.00083	20.7	1.4	1	23	722	744	722	744	0.98
19	28	8.4e-05	0.0082	17.6	3.3	1	23	750	772	750	772	0.98
20	28	1.5e-05	0.0014	19.9	0.3	1	22	778	799	778	799	0.97
21	28	1.5	1.5e+02	4.2	2.8	1	21	895	915	895	916	0.92
22	28	0.0016	0.15	13.6	6.1	1	23	1057	1079	1057	1079	0.96
23	28	0.00027	0.027	15.9	1.1	1	23	1085	1108	1085	1108	0.93
24	28	0.86	84	4.9	0.1	2	23	1117	1139	1116	1139	0.88
25	28	0.00029	0.028	15.9	0.1	1	23	1144	1166	1144	1166	0.97
26	28	6.7e-06	0.00065	21.0	1.1	1	23	1172	1194	1172	1194	0.98
27	28	4.7e-06	0.00046	21.5	1.8	1	23	1200	1222	1200	1222	0.97
28	28	0.0046	0.45	12.1	1.0	1	21	1228	1248	1228	1249	0.95

Sequence Information

Coding Sequence: ATGCCGATTGttcaaataaatgaatttgTAACACCCCAGAACAGAACGCCGAGGAAACGGGGTCGTCCCCGAAAAATAAGCGTATCACTCGAAGAAACTAAAACGAAAACAGACAAAGATACAGACGACGATCaaaacgacgacgacgacaaaaaaattaatttgcatGATGATAACATAGAAATTGAAATGGATTACACTGAGAAAGCTTCAGAAGAAGGAGGGGACGTCgcgaaatatttctgtcccaACTGCGTCACCCTTCAGACAATGACCGAAAAAGAACTGAGAAAACACTTCAAAGTAGCACACAGAGGCAAACGTCTTAGAAATATTCACCTCTATTCAGGTGAGCTACTGAAGTGCGAGATATGTCCGAAACaattcaaaacaaacaaaagtttGAAAGAACATCTCGAATTTCACAGCAACCAATACACTTGCGAAACGTGTTACTCATGTTTCCGAAAAATCGGCGAATACATAATTCATCTTCGTGCACATTCCGAGGAGAACATCTTTAAGTGCGTCGTGTGCGATTACAGCACCGAATCGATCAACGAGATCAAAGGCCACATATCGGACGATCACGAAGGGGACACTTACAAATACAAGTGCGTCATTTGCGACAAAGGTTTCCATTTGCTGTCGTGGTTCGAGGAACATAACAATTTTCACACAGGCACCAAACCCTTCGAGTGCGATTTCTGCGGAAAATTCTTCATGTATAGCCGTCATTTATACGTCCACAAGAAAACGACTCACGGTGTCGAAGGCGAGCCGGTCTTACACGAATGCGTTGTGTGCAAAAAACAGTATCAGCACAAGAACAGTCTGAAGCTTCACATGAACGTGCACACTGGAAACTTGGCCATTTGCGACATCTGCGGCAAGCAGTTGTCAAGCAAGGAAAAGCTAAAATTTCACATGAGAACCCACACGGGTTACAAGCCCTTCAGTTGCAACTATTGCGgtaaatgtttcaccaaaaaACCGATCCTTGTGGAACACGAACGCATTCACACAGGCGAGAAACCTTACGGTTGTCAGTACTGTCGCAAGGCTTTCTCGCAAAGATCGAGCTTGGTCATACACGAACGCGGTCATACCGGCGAACGCCCATACGTCTGCCATCTTTGTACCAAAGGGTTCGTCTCTAGGGCCATGCTCAACATACACATCAGGTCTTGTAAGGGCTATCTTAAGACTGAATCAGACGACGATGATGAAGATTTTGTTATAACAAGACGTCGAAAAATTGCGAAAGGTAGATCCAAAAGGACAACACTCAAGAAGAACAAGACGAAAACTCAAAAAACCAGCACCAACCCTATCGAAATAATTACCGTAAAAAAAGAAGGAATTGAAAGTGTCGATAAGAACAAGGCCATAACATGTAAATACTGCAACAACATTTTCTCTAACGAAAAATTGTTTCGTTACCACATGATGAGAGAAGAAGAACTTTATTATTGTCACGAGTGCGAGTGTTACGAAAAGCTGACGAAAATCGAACTTATCGAACATTGTAAAGCGCACGGGATCGACTATAAAAGTTCCAAAAACTTTTTCCGTCGAGCCAAGTCGAAGAGACCGCGTGTTAAACGGCCCGAGCGTTCGTTTTGTGAAATATGTTCCGCAGAATTCGATACGAAAGACGAACTTGAAAAACATTACGACGACTCGCACGAAAATCATTACGTGTGCGAAGTTTGTAACGCCGGTTTCAAGAAAATCGTTGATTACACCCTGCACATGTACTCGCACAGCGAAGACAACCTCTTCAAGTGCCCGCTGTGCCATTTCACATCGACCAAAGGTTACATAATCAAGGCCCATCTTCAGTCGGTTCATGAACAGTTCAAAAAGTACAAGTGCGAACTTTGCGCGGCAAAGAGACCTTTTCAATGCGACATATGCGGCGCCAAATTCATGTACTCGAGATATTTAAACTCTCACAAAAGATACCAACATCAATTCTCCAAAGATGAAGAACTCAAGTGTTCTGTATGCGGAAAAGTATGCACGACCACGAGGTCGTTGAGTAACCATCAACGCGTTAGACATCCAAAAGAGTTACTTGTGTGCCATTTTTGTGGTAAAACGTTTAGGGGAAAACAAAACCTTCTGTTACATTCGAGAATTCATACGGGCGAAAAGGCGTACACCTGTTCTTATTGCGGTAAGAAATTTAGCCGGAGAGGGTACATGTTGGAACACGAAAGGATTCATACCGGGGACAAACCGTTCAAGTGTCCTCATTGCAACAAGGGTTTTTCCCAACGTACTAGTATGGTCATTCATTCTAGAAAACATACGGGAGAGAGACCCTATGTGTGTCATATTTGTGGGAAGGGTTACGCCTCCAGGAATATGCTTACGAATCACTTGAGGACTTGCAAGGTGTTTAGTGAAGAGCAGCCGCCAACAAGTAGTCTTCCAATAAAGACTATTGAGGTCACTTTTTCCAATGGCTCGAACAGAGAAACTAGGAAAAGAAATGCTAAACGTAAGAAAATCAATAATAGCAACAAAGAAACTTCAAACGGAAAAAAGATCATTGTCAGTAAAGAAAATATGTTGTGTGTAAAAGAAGAACAAAAATCTATTTTAGCAGATTTTCTTCAATGCAATGACTTAGAGGAAACAGTTCTTAAAGATCAAGATAAATCAAAGAAACGATACACTTGCAGATTTTGTCGTAAAGTTTATAACGATAGAACAAAGTATCGATTTCATATGAACCAAGAagagaaaatatatttctgtCATCAGTGCGCAAACTGCGAAAAATTAACTAAACACGAGCTAATACAGCATTGCAAAATGCACGGCATTGACTATAAGAAAAAGGACAGATTCTTTCGAAGAGCGCAAGCAAAAAATCCCCGACTACGCGccaaaatacaattatttctcTGCGAAATATGTTCTTTGGAGTTTCCCTGCAAAAAACCGACCTTGACACGCATTACGAAACTGAACACAAAAAtcattataaatgcgaaataTGCTATGCAGGTTCCAACAGTCTCATCGATTACATATTTCATATGCAGACACATAGCGAAGGGTAAATCGTTAAAGTGCCCTCTTTGCACATTCTCCACCTCTAGCAGGTTTATAATCAAAGGTCACCTGGCGTCAGTTCACGAACAATTCAGAAAACACAAGTGCAAAATTTGCGGCAAACGATTTTCCGTTTATTCTCATTTTGTAGAACATAAAAACTTTCACACCGGTGAGAAACCGTTTCAGTGCGACACGTGTGGCAAAAAATTCATGTATTCGAGATATTTGAGGTCACACGTGGCTCTCATGCACACTGAGTGTTCTGAAAACGAACTCAAGTGTTCGATTTGCGATCAAGCGTTCCTTGCAGCGGGGCCACTCATAGAACATAAGCGCAGAAAACATCCAAAGTTCGTGCATGTCTGCGAAGTTTGCGGGAAAACATTTAGAGAACGTCTCGGACTTGCAGCACACGCTAAAATCCATTCGGAAATAAAATCGTATGCATGTTCAGTTTGCGAGAGGCGTTTCTCGAGGAGGTCATATTTGACCCAACACGAACGTATTCACACGGGGGAAAAACCGCACGTGTGTCCGCATTGTGGCAAGGCATTCACGCAACGCAGCAGCATGGTCATACACACCAGAGGTCACACTGGAGAACGACCTTATGTTTGCCAACTGTGTGATAAAAAGTTCACTTCTGGTAACAGGCTAACAAATCATAGAAAAAATTGCAAGGGGGCACCAACACCTACTTAa
Protein Sequence: MPIVQINEFVTPQNRTPRKRGRPRKISVSLEETKTKTDKDTDDDQNDDDDKKINLHDDNIEIEMDYTEKASEEGGDVAKYFCPNCVTLQTMTEKELRKHFKVAHRGKRLRNIHLYSGELLKCEICPKQFKTNKSLKEHLEFHSNQYTCETCYSCFRKIGEYIIHLRAHSEENIFKCVVCDYSTESINEIKGHISDDHEGDTYKYKCVICDKGFHLLSWFEEHNNFHTGTKPFECDFCGKFFMYSRHLYVHKKTTHGVEGEPVLHECVVCKKQYQHKNSLKLHMNVHTGNLAICDICGKQLSSKEKLKFHMRTHTGYKPFSCNYCGKCFTKKPILVEHERIHTGEKPYGCQYCRKAFSQRSSLVIHERGHTGERPYVCHLCTKGFVSRAMLNIHIRSCKGYLKTESDDDDEDFVITRRRKIAKGRSKRTTLKKNKTKTQKTSTNPIEIITVKKEGIESVDKNKAITCKYCNNIFSNEKLFRYHMMREEELYYCHECECYEKLTKIELIEHCKAHGIDYKSSKNFFRRAKSKRPRVKRPERSFCEICSAEFDTKDELEKHYDDSHENHYVCEVCNAGFKKIVDYTLHMYSHSEDNLFKCPLCHFTSTKGYIIKAHLQSVHEQFKKYKCELCAAKRPFQCDICGAKFMYSRYLNSHKRYQHQFSKDEELKCSVCGKVCTTTRSLSNHQRVRHPKELLVCHFCGKTFRGKQNLLLHSRIHTGEKAYTCSYCGKKFSRRGYMLEHERIHTGDKPFKCPHCNKGFSQRTSMVIHSRKHTGERPYVCHICGKGYASRNMLTNHLRTCKVFSEEQPPTSSLPIKTIEVTFSNGSNRETRKRNAKRKKINNSNKETSNGKKIIVSKENMLCVKEEQKSILADFLQCNDLEETVLKDQDKSKKRYTCRFCRKVYNDRTKYRFHMNQEEKIYFCHQCANCEKLTKHELIQHCKMHGIDYKKKDRFFRRAQAKNPRLRAKIQLFLCEICSLEFPCKKPTLTRITKLNTKIIINAKYAMQVPTVSSITYFICRHIAKGKSLKCPLCTFSTSSRFIIKGHLASVHEQFRKHKCKICGKRFSVYSHFVEHKNFHTGEKPFQCDTCGKKFMYSRYLRSHVALMHTECSENELKCSICDQAFLAAGPLIEHKRRKHPKFVHVCEVCGKTFRERLGLAAHAKIHSEIKSYACSVCERRFSRRSYLTQHERIHTGEKPHVCPHCGKAFTQRSSMVIHTRGHTGERPYVCQLCDKKFTSGNRLTNHRKNCKGAPTPT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -