Basic Information

Gene Symbol
-
Assembly
GCA_947389935.1
Location
OX376705.1:11337967-11345074[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.029 7.1 8.7 1.7 1 23 402 424 402 425 0.94
2 11 0.0043 1.1 11.3 3.5 1 23 431 453 431 453 0.97
3 11 0.00091 0.23 13.4 3.0 1 23 508 531 508 531 0.95
4 11 3.5e-06 0.00085 21.1 0.8 2 23 548 569 548 569 0.97
5 11 3.4e-05 0.0085 17.9 5.1 2 23 1039 1061 1039 1061 0.96
6 11 0.00013 0.031 16.2 5.2 1 23 1067 1089 1067 1089 0.99
7 11 0.47 1.2e+02 4.9 0.5 2 23 1094 1116 1093 1116 0.86
8 11 0.00028 0.069 15.1 0.1 2 23 1123 1144 1122 1144 0.97
9 11 0.01 2.5 10.1 0.9 1 23 1150 1172 1150 1172 0.95
10 11 0.00035 0.085 14.8 0.6 1 23 1176 1198 1176 1198 0.98
11 11 0.026 6.4 8.9 5.7 1 22 1208 1229 1208 1232 0.92

Sequence Information

Coding Sequence
ATGTATTTCATGTCTGATTTTTGTCGGGTTTGCCTTCAAGGGGAAAAAGGACTGAAAGACATCATGAAAGACAAAGAAGCATCTGATAGTTTATATAGCAAATTAAAATTATGTGTGTCAGAAATCGATTGGTGTAAATATAAGAACATGTTTATGTGTGAGAAGTGTGTAACAAAGTTGAACACAGCTTTCGACTTTAAGTGGCAGTGTATAAAATCTGCAGAAATATTAAGAAACTTTTTAAATCAATTGGGTATTGAAGAAAATAAGACTGACTTGAAACGAAACGAGATAAATTCAACAATTACAGATGAAGAAAAAAAAGAACAAGCAGAACTAAAACAAACATCTTTTGTTCGTATTATGCCCCCTGATCAACAATTATTTACACCTGGTCAACTACAAAATGTGATAGTTTCACCCAATGCAACGCAAAGTACTTTTCCTAATCTATTTTTTAATTTAATCCCAACAAACTTATTGAAACCACAAAATCCGCCTCCTTTAAGTTCTACTACTAGGCCTTCGATGTCAAGTACAGTTTCGCCAGTAAAAGATGCAAATCAAAATATGTTTGTTAGCATAAACAATACTCTTCACAGAATTTTCCCTGTTATTTCTCCAACAAAGGATAACCCAGTTCAGTCATCAACAAATAAAACTGTTTTCCCAACGATTTCAACAAATAATGTAAAACCAGAAATAATTGCAAAGCCTGCAGTCAATGCTAAGGATGTGTCACATGTATTAACTGAAGAGTTGAGCATTGAGATTGATCCTTCATGCTTCGATCTGGAAGAGGAGAGCCCAGATAGTGTACATAAATCAGAAATGAACATTTTGAGAGACTGGGAAGACGTTATTGTAAGTAATAAAATATCCTCTGAGAATGACAATATAAATATCAAAACGTCCTTAAATAATTCGCTTCCTACACTGAACAAAATGCTGGAATTTAACAATGGCCTTACACATCCTCATATGGGAAATATTCAGAAAGAAACTAATAATCCACATACTCCAAGTGCTACAGTTGCTCCAAAGCAGATGCCACATATGGGCAGTTATGCGCCTATTCGCCCAAAATTGCCTGAACATCTGGCCACAGTGGATTTTGAAGAACAATTTGAGTTTTTTAATGCAGGACATTTTATGACACAGAAAGAACCCGAGAAATCGTCAGCCATAGATTGCATTAGAATATTTGCCTGCGAAATGTGTTCAGACACATTTGACTCTTTACAAAAATTAAACAGCCATATCAAACAACATCATTCGGGAAAGTTTCCGTACAGATGTAAATACTGTTTTACGGAGTTTGCAGTTCGGTCACAATTTAAAGAACATTTACATGCCCACTTGTCAGATTCCACCGGTAATTATACAAAAGATTCCATCACATTAGATGATTTAAATGCCGAACATCATGAATCATTAGTATTAAATTGTGTGAATTACAAGCCTGTTACAATACAAAAACCAGAACAAATAGAAGGAGAAGGTGAAGCTGAAACTGGCGAATTCAGGTGCGAACAATGTCCCAGAAGATTTAACAGTTTACATGGCTTATCTCGACACAGAGTACGAAAGCATAATTTTAAAGCAAAGAAAAAGTATTTTATAAAGGGCATGAAAAATGCCAGATGTGATATTTGTAATAGAGAATTTTCTACGCAGTCTTATTTGCAGTTGCATATTAAACTGCATTATCGTAAAAGTGATTTTAGGCGTAAAGTTTTTTGTAAGGAACAATACACTTCTGACAGTCACTTCCTAAACTTCAATGACAAAAATCAATACGAAGAATATAGCATGATAGACAATCATATGTTGGACGTCGATATTCACATGGATACTGACGAGTCATTTTCATTAGATGCTAATGTAGGAGATACATTTACAGAAAATGCTAATATTTTAATAAAAACTGTTAAGGGAAATAGTATGGAAACCTCGTTATCCACTTCTAATAATGATTCCACAATGGAAACTACTCAAACAGAAAGTTTATCAGAAAATTTTGCAATAGACAGCTCTTCTACTGAAACAGTTGATTCTTGTTTAGAAGATTCAACAAATCCTGATTTACCAGGTGACATAAATCCTAATGAACTTTTGAAACTTGATTTGAATGACATTTGTGATGATAAAATTAAAGACAAAAGTGAAAAAAGTAGAGAAGAACCGGTGGATAAATTTAAAAGCAAAGTTAAGCAAAACAAAAATGGAACTGAAAGCAAAAGCAGTATTGAAAATGGAAGTAAAGAAAATAATGACACTACATCAGAAATTGTTGATAGCTTTAAGAACAATTATGCCAATAATGCTATCAGTAAGGACGAAAAAGTCGAAGCCAAAGTCTGCGTTTCAATGGAGATTTTAGCTGAAAAAAATGTGGAACCAAAGAAACAAAAATGTGAATATCCTCTATTAAAAGAAAACGAAAAGAAGGAAAACTGTGATCCTCAGCCACTTAAAGATTTTACAGTAAGTGATGATTGTAATAAACATTCCATTAAAAACGACGACGTTACTGTATCTAATGTAGGTATAAAGTTGAAAATTAATTTACGAAACATAAAACAAAACAGTCGAGAGGAAAACGTGGAAAAAAACAGAGAACATTTCGATAAAGGAGTGACAGAAGTTGAACTAATAGCACCAAAACAGCAAGAACATACAGAAGAGTCAGCAATTAAAGTTATGGACGATTCAAAAAAATGCAAAGAGAAAACTAAAAAAAGTGGTGCTTCACGAACGTTATCTAAAAAACGTAAGGGAAGTTCCTCCAAAAAGTCTTCGAGAAAAAAATCCAAAACTGTCAAAATAAAGGAATCAACAACAGATCAGGCGCTCACGAAGGAAGAAATTGATGTTAAAAAAGAAGCAAACTTAAAATCACCAGAAAATGAGGATCTGACGTCAAATAATACAAGACTGACAGATAACGTAACAGATAAAGAAACGCTAAAAGAGGCAGAATCCGTGACACCAGCAACTAATATACCAGTAGACGTTAGCTGTTCAGCAGAAGATACAATCATGAACGAAACTGAAAACGAAAATCAAATGTTTTTTAGCGGTTATAAAATTGAGATTATCAATGGTCGACCCAAATGTAATTTTTGCAACAAACTTTTCAGCAGAAAACATGATTTAAAACGTCACATGAACAACATTCATTTGAAGGCAATAAAATACAAGTGTCATCTGTGTGATGTCACATTTTACGAAGCGTTTCATCTCACAAGACATCTGCGTCAGCACAATTGTTTCGTAACTTGCGCTGTTTGTCCGAAAAATTTCAGCGCATTACGAGATTTAAAATGTCACGTGGACTCTATTCATAAAGAGGATTCGTCTGTCCAGTGTGGGACTTGCAGTATTGTGTTTTCAAATTTGGAAGAATTAAAGGATCATATCCAGCAGCACGATAGAGAGGTAATATATAAGTGTCACCTTTGCATCGAGGAGTTCAGTGAATCTCGGGACTTAACCAAACACCTCGTTGGACATAGCGGCATGTACTCGTGTGCTACGTGTCAAGCTACCTTTGCGACCGAACATGAATTGAACTTACATCTCAAAGTGCACTCATTTAACGTTTCTGATGATACGAAATACGAATGCGAGGTTTGTCACAACAAATACAAAAAGAAACGATACTTGGCGAATCACATGAAGCATTCGAAACATAGTCGTAGTTTGGAAAAAAAGGACACGGATGAGGTGTTTGTTAACAGGGTAGAACGTAACAATTCCGATGATTCCACCTAG
Protein Sequence
MYFMSDFCRVCLQGEKGLKDIMKDKEASDSLYSKLKLCVSEIDWCKYKNMFMCEKCVTKLNTAFDFKWQCIKSAEILRNFLNQLGIEENKTDLKRNEINSTITDEEKKEQAELKQTSFVRIMPPDQQLFTPGQLQNVIVSPNATQSTFPNLFFNLIPTNLLKPQNPPPLSSTTRPSMSSTVSPVKDANQNMFVSINNTLHRIFPVISPTKDNPVQSSTNKTVFPTISTNNVKPEIIAKPAVNAKDVSHVLTEELSIEIDPSCFDLEEESPDSVHKSEMNILRDWEDVIVSNKISSENDNINIKTSLNNSLPTLNKMLEFNNGLTHPHMGNIQKETNNPHTPSATVAPKQMPHMGSYAPIRPKLPEHLATVDFEEQFEFFNAGHFMTQKEPEKSSAIDCIRIFACEMCSDTFDSLQKLNSHIKQHHSGKFPYRCKYCFTEFAVRSQFKEHLHAHLSDSTGNYTKDSITLDDLNAEHHESLVLNCVNYKPVTIQKPEQIEGEGEAETGEFRCEQCPRRFNSLHGLSRHRVRKHNFKAKKKYFIKGMKNARCDICNREFSTQSYLQLHIKLHYRKSDFRRKVFCKEQYTSDSHFLNFNDKNQYEEYSMIDNHMLDVDIHMDTDESFSLDANVGDTFTENANILIKTVKGNSMETSLSTSNNDSTMETTQTESLSENFAIDSSSTETVDSCLEDSTNPDLPGDINPNELLKLDLNDICDDKIKDKSEKSREEPVDKFKSKVKQNKNGTESKSSIENGSKENNDTTSEIVDSFKNNYANNAISKDEKVEAKVCVSMEILAEKNVEPKKQKCEYPLLKENEKKENCDPQPLKDFTVSDDCNKHSIKNDDVTVSNVGIKLKINLRNIKQNSREENVEKNREHFDKGVTEVELIAPKQQEHTEESAIKVMDDSKKCKEKTKKSGASRTLSKKRKGSSSKKSSRKKSKTVKIKESTTDQALTKEEIDVKKEANLKSPENEDLTSNNTRLTDNVTDKETLKEAESVTPATNIPVDVSCSAEDTIMNETENENQMFFSGYKIEIINGRPKCNFCNKLFSRKHDLKRHMNNIHLKAIKYKCHLCDVTFYEAFHLTRHLRQHNCFVTCAVCPKNFSALRDLKCHVDSIHKEDSSVQCGTCSIVFSNLEELKDHIQQHDREVIYKCHLCIEEFSESRDLTKHLVGHSGMYSCATCQATFATEHELNLHLKVHSFNVSDDTKYECEVCHNKYKKKRYLANHMKHSKHSRSLEKKDTDEVFVNRVERNNSDDST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-