Basic Information

Insect: Agonum fuliginosum
Gene Symbol: CTCF
Assembly: GCA_947534325.1
Location: OX384043.1:26899251-26905523[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00062 0.087 14.8 4.1 1 23 215 237 215 237 0.97

2 11 1.9e-05 0.0027 19.5 1.5 1 23 243 265 243 265 0.98

3 11 0.0014 0.2 13.6 3.8 1 23 271 294 271 294 0.95

4 11 0.019 2.7 10.1 5.2 1 21 300 320 300 322 0.95

5 11 0.00019 0.027 16.4 1.9 1 23 328 350 328 350 0.99

6 11 1.3e-05 0.0018 20.0 1.8 1 23 356 378 356 378 0.98

7 11 0.00049 0.069 15.1 1.4 1 23 386 409 386 409 0.97

8 11 3e-05 0.0042 18.9 2.2 2 23 416 437 415 437 0.97

9 11 0.00025 0.036 16.0 0.3 1 23 443 465 443 465 0.98

10 11 2.7e-06 0.00038 22.2 2.6 1 23 471 494 471 494 0.96

11 11 3e-08 4.3e-06 28.3 0.8 1 23 508 530 508 530 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00062	0.087	14.8	4.1	1	23	215	237	215	237	0.97
2	11	1.9e-05	0.0027	19.5	1.5	1	23	243	265	243	265	0.98
3	11	0.0014	0.2	13.6	3.8	1	23	271	294	271	294	0.95
4	11	0.019	2.7	10.1	5.2	1	21	300	320	300	322	0.95
5	11	0.00019	0.027	16.4	1.9	1	23	328	350	328	350	0.99
6	11	1.3e-05	0.0018	20.0	1.8	1	23	356	378	356	378	0.98
7	11	0.00049	0.069	15.1	1.4	1	23	386	409	386	409	0.97
8	11	3e-05	0.0042	18.9	2.2	2	23	416	437	415	437	0.97
9	11	0.00025	0.036	16.0	0.3	1	23	443	465	443	465	0.98
10	11	2.7e-06	0.00038	22.2	2.6	1	23	471	494	471	494	0.96
11	11	3e-08	4.3e-06	28.3	0.8	1	23	508	530	508	530	0.97

Sequence Information

Coding Sequence: ATGGCTGCACAATTTACTACTGCCCAACATATTAAGCTAGAAGCCACAGAATCCGGTGAGAACATCACCGAGATACAGAACTACTTGGAGACTTTCAATAAGGAAATCGAAAGCACCGATGGGACCACTACAATCACACAAGTCACAGAGGAGGAAGGCGATGGCGAAGGCGAGGACGGAGAGACCGAAGAGGGCACGTACTTCATCGACCAGAGCGGCCACTACTACTACCAGGCGGCCAGCGACCAGCAGCCAGTCATGGCCGTGGTGTCCGGCGGAGACGACGAGGAAGAGTTCGTCATCCAGCCCGACGGCGACGGTGACGGCATGGACGGTGAAGAGGCGACCATCATCACCGGCGAGCCGGGCAGCAACCAAGTGCTCATCAACTCCGGCGACGCTTACCAGACCGTGACCATCGTGCCCAGCGACACCAACCAGGGCGAGGTCAGCTACGTCCTCATTGTGCAGCAAGACGAAACCGACGGCAACAAGGACTCCGAGGCTGGTGACGACCAGGACATGACCGTCTACGACTTCGACGAAGGCGAGGAAGGCGGCCTCGTGGACTCGGAAGCTGAAGATGACAAGTCTAAGATTGTCAAGATACTTCCCAGGAAGTCGCAGACTGTGACGCAGGCGCATATGTGCAATTATTGTAACTACACTAGTCCGAAGCGGTACTTGTTGTCGCGgcacatgaagtcgcattcggaagaacggccgcacaagtgtagtgtatgtgaacgaggctttaagacgctcgcttcgctgcagaatcatgtcaacactcacacgggcatcaagccgcatcactgcaagttctgcgactctgccttcactaccTCCGgcgagctggtccgccacgtgcgctaccgacacacgcacgagaagccccacaagtgccacgagtgcgactacgcgtcagtagaactctcgaaactcaaacgtcacatccggtgccacacgggggagcggccgtaccagtgtccgcactgcacgtacgcctcgcctgacaccttcaagctcaagcgccacctgcgcatccacacgggggagaagccctacgagtgcgacatctgccacgcgcgcttcacgcagagcaactcgctcaaggcccacaagctcacgcacaacgtcggcgacaagcccatcttccagtgcgagctctgccccaccacctgcggccgcaagaccgatctccgcatccacgtgcagaagctgcacaccagtgataaacctctcaagtgcaaacgatgcggcaaatcgttcccggaccgctacagctacaagatccacaacaagacgcacgagggggagaagtgcttcaagtgcgagctctgcccctacgcgtccatcagcgcgcgccacctggagtcgcacatgctcatccacacggaccagaagccgttccagtgcgagcagtgcgaccagtcgttccgccagaagcagctgctgaagaggcaccagaacctgtaccacaaccccacctacattcctccgccTCCTCGGGAGAAGACGCACGAGTGCCCCGAGTGCGGCAGGGCCTTCAGGCACAAGGGAAACCTCATCCGGCACATGGCTGTGCACGACCCCGAGAGCAGCGTCCAAGAGAAACAACTCGCGCTCAAGATTGGCCGCCAGAAGAAAATACAAATCATTGACGGACAACAGGTGGAGGTGATGCCGGGCATGGACTCGGACTCTGAGGACGACGGGGAGATGATGGCCGTGGAGGGGGCGGACGGCCAGCAGTACGTGGTGCTGGAGGTGATCCAGCTCGACGGCGACGACAACCAGACCGTGGCCGTCGTCTCCGGCGGCGACGAGGGCGACCTCACAGAGGAGCACATCATCTCCGGCGACCTCAACGACGAGGACGTCATCAAGGCGCTGCAGACCTCCCGGAGGCTGCAGCAGAAGGAGGAAAAGAAAGAGGAGCATGATGACATGAGCAACTGCTTCGGCTTTGATGACGAAGAAGACGACGAAGAAGATGAAGATGATGAACAAGAAGTAGACATGAAGCCAGGAAAACACACCATCACGCTACTTAGTGACCAGATGATGGTAGACGAAGAAGACGACGACTAG
Protein Sequence: MAAQFTTAQHIKLEATESGENITEIQNYLETFNKEIESTDGTTTITQVTEEEGDGEGEDGETEEGTYFIDQSGHYYYQAASDQQPVMAVVSGGDDEEEFVIQPDGDGDGMDGEEATIITGEPGSNQVLINSGDAYQTVTIVPSDTNQGEVSYVLIVQQDETDGNKDSEAGDDQDMTVYDFDEGEEGGLVDSEAEDDKSKIVKILPRKSQTVTQAHMCNYCNYTSPKRYLLSRHMKSHSEERPHKCSVCERGFKTLASLQNHVNTHTGIKPHHCKFCDSAFTTSGELVRHVRYRHTHEKPHKCHECDYASVELSKLKRHIRCHTGERPYQCPHCTYASPDTFKLKRHLRIHTGEKPYECDICHARFTQSNSLKAHKLTHNVGDKPIFQCELCPTTCGRKTDLRIHVQKLHTSDKPLKCKRCGKSFPDRYSYKIHNKTHEGEKCFKCELCPYASISARHLESHMLIHTDQKPFQCEQCDQSFRQKQLLKRHQNLYHNPTYIPPPPREKTHECPECGRAFRHKGNLIRHMAVHDPESSVQEKQLALKIGRQKKIQIIDGQQVEVMPGMDSDSEDDGEMMAVEGADGQQYVVLEVIQLDGDDNQTVAVVSGGDEGDLTEEHIISGDLNDEDVIKALQTSRRLQQKEEKKEEHDDMSNCFGFDDEEDDEEDEDDEQEVDMKPGKHTITLLSDQMMVDEEDDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01040310;
90% Identity: iTF_00470196;
80% Identity: -