Basic Information

Insect: Agonum fuliginosum
Gene Symbol: ZEB2_1
Assembly: GCA_947534325.1
Location: OX384042.1:6676207-6678757[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 9.1e-05 0.013 17.4 1.2 3 23 228 249 227 249 0.93

2 11 5e-08 7e-06 27.6 0.8 1 23 253 275 253 275 0.98

3 11 0.00061 0.086 14.8 1.7 1 23 283 305 283 305 0.95

4 11 9.3e-05 0.013 17.3 0.8 1 23 311 333 311 333 0.98

5 11 8.5e-05 0.012 17.5 1.5 1 23 342 364 342 364 0.97

6 11 7.9e-06 0.0011 20.7 1.5 1 23 370 392 370 392 0.95

7 11 0.00016 0.023 16.6 2.6 1 23 398 420 398 420 0.99

8 11 2e-05 0.0028 19.4 1.6 1 23 426 448 426 448 0.98

9 11 0.00027 0.038 15.9 0.4 2 23 455 476 454 476 0.97

10 11 3.5e-05 0.0049 18.7 2.1 1 23 482 504 482 504 0.99

11 11 3.3e-08 4.6e-06 28.2 0.3 1 23 510 532 510 532 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	9.1e-05	0.013	17.4	1.2	3	23	228	249	227	249	0.93
2	11	5e-08	7e-06	27.6	0.8	1	23	253	275	253	275	0.98
3	11	0.00061	0.086	14.8	1.7	1	23	283	305	283	305	0.95
4	11	9.3e-05	0.013	17.3	0.8	1	23	311	333	311	333	0.98
5	11	8.5e-05	0.012	17.5	1.5	1	23	342	364	342	364	0.97
6	11	7.9e-06	0.0011	20.7	1.5	1	23	370	392	370	392	0.95
7	11	0.00016	0.023	16.6	2.6	1	23	398	420	398	420	0.99
8	11	2e-05	0.0028	19.4	1.6	1	23	426	448	426	448	0.98
9	11	0.00027	0.038	15.9	0.4	2	23	455	476	454	476	0.97
10	11	3.5e-05	0.0049	18.7	2.1	1	23	482	504	482	504	0.99
11	11	3.3e-08	4.6e-06	28.2	0.3	1	23	510	532	510	532	0.98

Sequence Information

Coding Sequence: ATGAATAACGCCAGAACTTGTAGGACTTGTTTAGAAGAAGAAATACCTATGATTTCTTTATACCAGTGTTTTAAAGATATTGATGAACATATACATTTAAATCATATAATAAAAGAGTTAGCGAAAATACATATACAGATAGATGATGGCCTTCCGGATAAAATCTGTGAATTTTGTTTGGAAGAATTAAAAAGAACTTTTAAATTTATCACACAAATACAAGACTCAGATAAATCTCTTCGTTCTGTAGAAGTATTGGAGACATCGTTAAAGGCTGATAGTTTTATTGAAGAATATTTAGAAGAGGAATTCTATAATACAGATGTAAAAACGAATATTAAACAGATTAGAATTAAACAAGAGAATATTCCTGTTGTAAGAGTGGATTTTAAAACAAATAGAAATGATGATAATATGTCAATTGACAGCTATAGATCAGACGAGGATGTAGATGATCCCGAAGAAAGAATTGTAGAAGATCTTCAAGAAAACAAAGCAGATGATCTTACAAGAAAAAGTTTGGACAATCGTGAGAAAACACATAAAAGTGCCAATATACCAGATTCGTATGAAAATAGTATAAATGAACGTGAGCATGATTATAGCAAACCACAAGAACGAAGCAAAGATGGTAAGAATCCATCCGACCAAGATACTAAAAAAGATAATTTGAAACCTATGTGTAATATATGTGATAAAATTTTTGAATCAAAAAGAAGTTTGAAATTACATATACACGAAGAACATGAGTTTCAGtataaatgtgaatattgtgaaaaatcatttccacaaagcatgaatttaaaagttcatatgagagcacatgttcctgatgataaaaaaaaattcagttgccaagaatgtagtgctgtattttcatatgaatatcaattaacccgacattcatttaagcataaagatgagaaaccatttccttgtccaaaatgcgacaaagggtgtctcactgcagatagtttaaagcgtcatttaaaagtgcatgaggaaaactacgcaaaaccaactcacgtttgtcaggtgtgtttcaaagaattttcctatccaagttttctggctgagcatatgaagaaccataccggagaaaaaccattcctatgttcacattgtgggaaaggttttcggcaaaaaggagctttactttaccatgtacgaagtcatcagaatatcaggccatttaaatgtaagctgtgtgagcattcgtttgtgtcaaaagggatcttaagagttcatatgcgcagacatacaaatgagagaccgtatgtttgtgatatttgtggacgggctttcaggcagtcatcagattgcagaatgcatcgacggatacaTTTCGGCCTTAAATTAGTCGAGTGTAGCGTTTGCAAGAAAAAAATGTCTACCACAGgacaattaacaatacacatgcgggtccacacaggcgaaaaaccatattcttgtacagaatgtttaaaaagatttgcaacgcggacagttttatcgaagcatcaacgtactcataccggagaaaagccctatatttgcagtgtttgcggcagagcattttcacaatctagttccttaaatacgcatatgaaaattcatttaagaaccaaagaaaaCGAAAAAAAGGAGAAAGAAAAACCTAAACAACCTGTTATAATTGTCAAAGTCAAGTAA
Protein Sequence: MNNARTCRTCLEEEIPMISLYQCFKDIDEHIHLNHIIKELAKIHIQIDDGLPDKICEFCLEELKRTFKFITQIQDSDKSLRSVEVLETSLKADSFIEEYLEEEFYNTDVKTNIKQIRIKQENIPVVRVDFKTNRNDDNMSIDSYRSDEDVDDPEERIVEDLQENKADDLTRKSLDNREKTHKSANIPDSYENSINEREHDYSKPQERSKDGKNPSDQDTKKDNLKPMCNICDKIFESKRSLKLHIHEEHEFQYKCEYCEKSFPQSMNLKVHMRAHVPDDKKKFSCQECSAVFSYEYQLTRHSFKHKDEKPFPCPKCDKGCLTADSLKRHLKVHEENYAKPTHVCQVCFKEFSYPSFLAEHMKNHTGEKPFLCSHCGKGFRQKGALLYHVRSHQNIRPFKCKLCEHSFVSKGILRVHMRRHTNERPYVCDICGRAFRQSSDCRMHRRIHFGLKLVECSVCKKKMSTTGQLTIHMRVHTGEKPYSCTECLKRFATRTVLSKHQRTHTGEKPYICSVCGRAFSQSSSLNTHMKIHLRTKENEKKEKEKPKQPVIIVKVK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -