Basic Information

Gene Symbol
-
Assembly
GCA_963693445.1
Location
OY856333.1:5137275-5143559[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 5.9e-05 0.004 18.2 5.9 1 23 46 69 46 69 0.95
2 11 0.07 4.8 8.5 0.6 2 23 79 100 78 100 0.95
3 11 0.00021 0.015 16.5 2.7 2 23 106 127 106 128 0.95
4 11 0.0043 0.3 12.3 5.6 1 23 134 156 134 156 0.96
5 11 1.3e-05 0.00092 20.2 0.5 1 23 162 184 162 184 0.98
6 11 0.18 13 7.2 10.8 1 23 209 232 209 232 0.95
7 11 2.4 1.7e+02 3.7 1.6 2 22 241 260 241 262 0.71
8 11 0.00047 0.032 15.4 6.0 2 23 268 289 268 290 0.95
9 11 0.002 0.14 13.4 2.5 1 23 296 318 296 318 0.96
10 11 1.3e-05 0.00092 20.2 0.5 1 23 324 346 324 346 0.98
11 11 5.6e-05 0.0039 18.3 2.6 1 23 352 375 352 375 0.97

Sequence Information

Coding Sequence
ATGTTGGAGAAACCCCGGGCCGCGACTTACGTGGAATttaaatggaataaaaatgcgGTCCTTATTTGGTTCTTGTTCGATGCAAATGACGATCCACCGTTCACGATCACCGTCGCCGCCGATGGGACCAAAGACTTCAGCTGCAATACATGCGGCAAATGCTTCAAAAGACGCGACGGATTCTCTAAACATTATAAATTTGTACATCTCAAGATACGACCAGAGGCGTTTAAGAGTTGCCAAATGTGTGGCGAGAAATATAATGCACACAGTAGGGCAGCTCATATGGAAACCGCCCACGGTGTCCCAGCACCGCAATGTAATGTTTGCAACAAAAAGTTTAGCAAGCCCTTCAAGGTGTTGGTTCATCAGAGAATACATCACATGGGCGAAAAGAAACATTCTTGTACTGTTTGCGATATGAAATTCGGAACATATTATCACCTAAAAACACATTCTTTAAAACATGCTCCTGAGAAGTCGTACGTGTGTGACATTTGCGACAAATCGTTTAAATGGAAGAACAATCTTGTAACGCACACTATGATGCATTTGGACGTTAGAACGCAAGTTTATGACGATCTACCATTCACGATCACGATCGCCGCCGATGGGACCAAAGACTTCAGCTGCAATACATGCGGCAAATGCTTCAAGTGTCGCAAAAATTTCTCCCAACATTACAACCACGTGCATCTGAAGAAACGACCTAAGCTTAGGAGTTGCCATATGTGCAGCGAGAAATTTGCTTCACACAAGAGGGCAGCTCATATGGAATCCGCCCACGGTGTCCCAGCACCGCAATGCAATGTTTGCAACAAAAAGTTTTGCAAGCCCTTCAAGTTATTGCTTCATCAAAGAATACATCACATGGGCGAAAAGAATCATTCGTGTACTGTTTGCGATATGAAATTCGGAACATTATATCTCCTAAAAACACATTCTTTAAAACATACTCCTGAGAAGTCGTACGTGTGTGACATTTGCGACAAATCGTTTAAATGGAAGAACAATCTTGTAACGCACACTATGATGCATTTGGACGTTAGAACGCATGTCTGTTTGGTGTGCTCTGAAAAGTTTGTACAACAGAGCAGCTTGACCTACCATATGAAGAAGCGACACCCTGAAGTGCACTGA
Protein Sequence
MLEKPRAATYVEFKWNKNAVLIWFLFDANDDPPFTITVAADGTKDFSCNTCGKCFKRRDGFSKHYKFVHLKIRPEAFKSCQMCGEKYNAHSRAAHMETAHGVPAPQCNVCNKKFSKPFKVLVHQRIHHMGEKKHSCTVCDMKFGTYYHLKTHSLKHAPEKSYVCDICDKSFKWKNNLVTHTMMHLDVRTQVYDDLPFTITIAADGTKDFSCNTCGKCFKCRKNFSQHYNHVHLKKRPKLRSCHMCSEKFASHKRAAHMESAHGVPAPQCNVCNKKFCKPFKLLLHQRIHHMGEKNHSCTVCDMKFGTLYLLKTHSLKHTPEKSYVCDICDKSFKWKNNLVTHTMMHLDVRTHVCLVCSEKFVQQSSLTYHMKKRHPEVH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-