Basic Information

Insect: Agonopterix heracliana
Gene Symbol: Zfa
Assembly: GCA_963693445.1
Location: OY856330.1:10582376-10595763[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0024 0.17 13.1 1.2 1 23 239 261 239 261 0.99

2 11 0.077 5.3 8.4 1.9 1 23 268 290 268 290 0.98

3 11 5.9 4.1e+02 2.5 0.6 1 20 294 313 294 317 0.73

4 11 1.2e-06 8e-05 23.6 3.0 1 23 324 347 324 347 0.95

5 11 8.4e-05 0.0057 17.7 0.1 2 23 354 376 353 376 0.95

6 11 0.00066 0.045 14.9 0.4 1 23 389 411 389 411 0.96

7 11 0.00093 0.064 14.4 1.1 1 22 417 438 417 442 0.93

8 11 0.00031 0.021 15.9 1.1 2 23 451 473 450 473 0.95

9 11 0.0002 0.014 16.5 0.2 1 23 479 502 479 502 0.97

10 11 1.7e-05 0.0012 19.9 0.1 1 23 511 533 511 533 0.98

11 11 0.02 1.4 10.2 0.1 1 23 539 562 539 562 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0024	0.17	13.1	1.2	1	23	239	261	239	261	0.99
2	11	0.077	5.3	8.4	1.9	1	23	268	290	268	290	0.98
3	11	5.9	4.1e+02	2.5	0.6	1	20	294	313	294	317	0.73
4	11	1.2e-06	8e-05	23.6	3.0	1	23	324	347	324	347	0.95
5	11	8.4e-05	0.0057	17.7	0.1	2	23	354	376	353	376	0.95
6	11	0.00066	0.045	14.9	0.4	1	23	389	411	389	411	0.96
7	11	0.00093	0.064	14.4	1.1	1	22	417	438	417	442	0.93
8	11	0.00031	0.021	15.9	1.1	2	23	451	473	450	473	0.95
9	11	0.0002	0.014	16.5	0.2	1	23	479	502	479	502	0.97
10	11	1.7e-05	0.0012	19.9	0.1	1	23	511	533	511	533	0.98
11	11	0.02	1.4	10.2	0.1	1	23	539	562	539	562	0.92

Sequence Information

Coding Sequence: ATGGAAGAAACCCTTGGTATAGCAGAAAACAGTTGTTGCTACGGTTGTTTGTGTCGAGACGATGTCAACCCTTTACATTGTTATAAAGTGCAGAACGAAGCTTTGAAAGCTATATTTCAGACGGACTCAATATCGTTCTGCTATCTGTGCAGACGGAGAGCTCAACAAGCTGAGttgttcatacaaaatgtacagaGCAACCAAATATTATTGGAAAACTTTCATAATATAACAGATTCAACTctagaaacaataaaaaaccaAACCCAACCGTTAACAAACTTAACCCACTTTCCTCTAGACCTCATAGAGTTGGGTAACAACGATGAAACGAATGAGGAAGAATCATTCTCCGTCATCAACAATAGTagcaaagaaattaaaataaaattggaaTTGAAAGATGAAgacaatgatttcaatttggagGGAGAGTATCTTGGAGAAGATAATGATTTGGATTCATATGTCAAAGAAGAAGATGAGTATCCATTGAAATTATTAAAAGAAGAACTAGAATTAGAaggaatcaaaataaaatgtctaAGGAAAAGTGTGAAGAAGGGAAGAGTAAAAAGAAAAGGCACAAAAGAGAAGCAAACGAAAGAGGATAAAATAAAAGACTTAAAAATAGAAACCCTGTATATAACAAGAGAACAATGTATGGAGGAGAGAACCAAGATGGCTGccgataaaaaatatataaattcagTTTACAAATGCGAGGATTGCATCAaaggatttaattttaaagcTAGCTACGATAAACATATGGAAAAACATAGTGAGAGTAATGGTGACTACGAATGTGATATATGCAAGCAAAGAATGGGTTCAGAAGAGAAACTACATAGTCATCAGAGATACCATAATTTACGTTACAAATGCAGTGAATGCAAGTTAATTAGGATAAGTCGGTTGACGATCAAGGATCACTACACTGCCTTCCATTGCCACGGCTACCATCAGTACAATTGCCCTCATTGCTCTAAAACTTTCAAACGGCAGGTGTCGCTGAGGAAGCACATATCGTACGCACACAAGCACAAAGAACGCGTACAGTGCGCGTACTGCAGTAAGACTTACGTCAGCAAGGAGGCTCTGAAAGCGCATCTCATTGTGAGACATCCGAACGAAGTGTCAGCGGGTAAGGTGCCCAAACAGCACGTGTGCCAGGAGTGCGGGATGGCTTTCAGCGCGCCCTCCCGCCTCAGGAACCACAGCATCAAACACACCCACCGGAGGGACTTCTACTGCGTCGAGTGTGACAAGAGCTTCAAATCTGATTCCATTCTAAAACATCATTTGAAAACAGCTATGCCACACACCAACTACTTAGAATTACCTCTACCCTGCCTACACTGCGACAAAAGATTTGCTATAAGAAGAGATTTAGAAAGGCACACGAACAGAGTCCATCTCAACATAAAACCATTCCAATGTGATAGGTGCGAAAAGGCCTACATAAATCCGTGGTCTCTCAACGAGCACAAACGCTTGGTCCACGAGGGGTACAAACGACCCCTCAAGTACCCCTGCCCGATGTGCGATAAAGTCTTTGACCGCAACCAAATCCTAAAAGGTCACATCCGAACCCACACCGGCGAAAGACCTTACCAATGCAGCAAATGTCCAGCGCAGTTCAGTCAAGCGAGCATACTGGGCACCCATGTTAAACTAATACACCTAAAACTTACCAGAGATGGACGACCTAAGAATCCTAATGCTATAAAATAG
Protein Sequence: MEETLGIAENSCCYGCLCRDDVNPLHCYKVQNEALKAIFQTDSISFCYLCRRRAQQAELFIQNVQSNQILLENFHNITDSTLETIKNQTQPLTNLTHFPLDLIELGNNDETNEEESFSVINNSSKEIKIKLELKDEDNDFNLEGEYLGEDNDLDSYVKEEDEYPLKLLKEELELEGIKIKCLRKSVKKGRVKRKGTKEKQTKEDKIKDLKIETLYITREQCMEERTKMAADKKYINSVYKCEDCIKGFNFKASYDKHMEKHSESNGDYECDICKQRMGSEEKLHSHQRYHNLRYKCSECKLIRISRLTIKDHYTAFHCHGYHQYNCPHCSKTFKRQVSLRKHISYAHKHKERVQCAYCSKTYVSKEALKAHLIVRHPNEVSAGKVPKQHVCQECGMAFSAPSRLRNHSIKHTHRRDFYCVECDKSFKSDSILKHHLKTAMPHTNYLELPLPCLHCDKRFAIRRDLERHTNRVHLNIKPFQCDRCEKAYINPWSLNEHKRLVHEGYKRPLKYPCPMCDKVFDRNQILKGHIRTHTGERPYQCSKCPAQFSQASILGTHVKLIHLKLTRDGRPKNPNAIK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00027120;
90% Identity: iTF_00027120;
80% Identity: -