Amic015950.1
Basic Information
- Insect
- Agara michaeli
- Gene Symbol
- -
- Assembly
- GCA_018245675.1
- Location
- DWDX01016059.1:496-2562[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 2.2e-05 0.0017 19.3 0.2 1 23 122 144 122 144 0.97 2 11 0.0039 0.32 12.2 3.3 1 23 304 327 304 327 0.97 3 11 0.00029 0.023 15.7 1.3 1 23 331 353 331 353 0.98 4 11 5.8 4.6e+02 2.2 3.2 2 23 375 397 374 397 0.88 5 11 0.013 1 10.5 1.7 1 23 401 424 401 424 0.98 6 11 0.24 19 6.6 0.3 2 23 447 469 446 469 0.90 7 11 2.2e-05 0.0018 19.3 2.0 2 23 480 501 479 502 0.95 8 11 0.0043 0.34 12.1 1.9 2 23 518 539 517 539 0.96 9 11 0.017 1.4 10.2 0.3 1 23 545 567 545 567 0.96 10 11 0.56 45 5.4 2.9 1 22 573 594 573 597 0.90 11 11 0.0055 0.44 11.7 0.5 1 23 649 671 649 671 0.98
Sequence Information
- Coding Sequence
- ATGGATCTAGAAAAAGTTCACGTAAAAGAGGAATTGGAATTAACAGAGACACATTTAATACCTGATAAGGTTACAACGACAACAGCGATGAGTCCGCAAGATGAAATGTTACAATCTGAGGTCAATACTTTAGTTATAGACATACATCCATTATTACACTCCGATACTATATCCATGCCTGAAATGGACAAGCCTGAAGAAATCTTGCCCACTACATACAGCCCTAATGATAATGACGATGGTCCTGCTAGTTACGATGATATATTTCAGCTAAATTCAATAACTGGCAATGAACTTTCACTCGAGCAGGAAGCTTACGGATTGTTAAAGGCAAAATGTCAAAAAGACGTAGAAGACAAGCAGTTCATATGTCCAAAGTGCCCAAAGGTATCGAAGACTATAATGCAACTTAAGAGACACATGGCTGTCCACGATTCCATAGACAAACGCGCATTGGGCATTATAAAAGGATTGAAGACAAGAATTGAAAATCGAAAAAAGAAACTCCAGGAATTGGACGATGACTATGAGATAGGAAATGATGATGCAGAGCTAGATGACGATCAAGATGCAAACAACCCTATTGCTTCGGGACGTAAAATAAGGATAGACAATCGCAATAAGAGACGCAAAGCGCAAGAAGGTGGAGTGAACTGCAAAGGGgtgaagaaaagaaaaaagaaattcaaagACGATCCAGAGGAAAAATTCTCTATCCGAATACGTAGCTATAAACAAGACGGTGATGTCAACGAAGATAGTAAACCagaatatgatattaaaattattaaacaggAGAATCTGAAGAAAGAAGGCTATCAATGCACGTGTGGGAATACTTTTCAAAGGAAGAGTCGCTTGGAAACATGTCTGAGGTCACACAATATGCTGCCTGATACAAATTCCTGTTTTTCCTGTCAGTCTTGCACGAAACAGTTCCACGACAAAAACGAACTCGCATTGCATCGTCGGCGGATACATCGGAAACGATTCCCTTGTAAGTTTTGTCCTACAGATTACAATACGCGGAAAGAGCTTTTCAAACATCTGCAAATCCATCAGAAAGTACAGTTGATGGAGTACAAGGTGATATCCGAGGTGATGAAGGGAAAACAGAAGCTGAGATGCTTCATGTGCGCGAAGACGTGTACAGAACTCTCGGAACTGAAGTGTCACGTGATGGACGACCACAAGGAGCCGTACACGTGTCCGCACTGTCAGGGCACGTTTTCGAAAATAATAGATTTCGGTAATCACACGAAAACCATGCATCCCGAGGTTGAAGGGCAGTCGGTTTTGGATGTTCTCGAGGCGTTCTCGAAATTGGTGAAGGCGTGGAAGTGCGAGGAGTGCGAGCTGCAGTTCCACGAGGCGGACAAATTGGCGCTACACCAAGTTGAGAAACATAGTCCGGAATTGAAAATGGAGTCACCGGTTCAGTGTACGGACTGTCGGCGGGTGTTCGTCAGTCAGAAGGGTTTGACGTCGCACAGACGTATACATCACAGCACCGACAGCGCGGATGAATCGGAAACCGTCGAGAGAGGTGTCATGTGTGTCGAGTGTCGCAAGATCTGCAAGGACACCACGGCGTTGACGTCGCACATGCGTTTCCATTCCCAGGACAGGAAGTATCCCTGCAGATTCTGCGACTTTCGTTTCGCCACGCCCGAGAAGAGAAAGGCGCACGCCGAAATACACACGGGCGACATGAAGTTCGTCTGTTTCATCTGCGAGTACCAGTGCAGCTCGGAGAACAGGTTGAACCAACACAAAATGTCTCTGAAGCATCTGAACATGAGGGAGTTTTTGAGAACGGGAATCCCATTAGTCGCGGAGGAGTCCACGTCCAAAAAGGAGAAGTCCAAGGACACTTCTAAAAGGAAGAGATTCGAAAAGAAGAAGGAGGATGGAAACGAGAGCAACTCGTTCTCGGATGACGAATACATCTGTGATATCTGCGGAGATAAATTCTCGAACGAGACCAAAATGCTGGAGCACAAGCAGACGCACCCGTTCATCGAGTTTCCAAACGAAGACAAACCTactaggatattttttaagtaa
- Protein Sequence
- MDLEKVHVKEELELTETHLIPDKVTTTTAMSPQDEMLQSEVNTLVIDIHPLLHSDTISMPEMDKPEEILPTTYSPNDNDDGPASYDDIFQLNSITGNELSLEQEAYGLLKAKCQKDVEDKQFICPKCPKVSKTIMQLKRHMAVHDSIDKRALGIIKGLKTRIENRKKKLQELDDDYEIGNDDAELDDDQDANNPIASGRKIRIDNRNKRRKAQEGGVNCKGVKKRKKKFKDDPEEKFSIRIRSYKQDGDVNEDSKPEYDIKIIKQENLKKEGYQCTCGNTFQRKSRLETCLRSHNMLPDTNSCFSCQSCTKQFHDKNELALHRRRIHRKRFPCKFCPTDYNTRKELFKHLQIHQKVQLMEYKVISEVMKGKQKLRCFMCAKTCTELSELKCHVMDDHKEPYTCPHCQGTFSKIIDFGNHTKTMHPEVEGQSVLDVLEAFSKLVKAWKCEECELQFHEADKLALHQVEKHSPELKMESPVQCTDCRRVFVSQKGLTSHRRIHHSTDSADESETVERGVMCVECRKICKDTTALTSHMRFHSQDRKYPCRFCDFRFATPEKRKAHAEIHTGDMKFVCFICEYQCSSENRLNQHKMSLKHLNMREFLRTGIPLVAEESTSKKEKSKDTSKRKRFEKKKEDGNESNSFSDDEYICDICGDKFSNETKMLEHKQTHPFIEFPNEDKPTRIFFK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01153287;
- 90% Identity
- -
- 80% Identity
- -