Basic Information

Insect: Agara michaeli
Gene Symbol: ZFHX3
Assembly: GCA_018245675.1
Location: DWDX01000044.1:21432-33767[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.00032 0.026 15.6 1.8 2 23 11 33 10 33 0.95

2 18 8e-05 0.0064 17.5 0.7 1 23 65 89 65 89 0.92

3 18 0.012 0.95 10.7 0.4 1 22 137 158 137 161 0.91

4 18 0.0048 0.39 11.9 2.4 1 23 548 571 548 571 0.94

5 18 0.087 7 7.9 0.0 1 23 578 601 578 601 0.95

6 18 0.0081 0.65 11.2 4.1 2 22 656 676 656 679 0.91

7 18 0.93 75 4.7 1.1 1 23 691 716 691 716 0.91

8 18 0.015 1.2 10.4 1.3 1 23 734 756 734 756 0.97

9 18 0.0018 0.14 13.3 0.3 2 23 763 785 762 785 0.96

10 18 0.00031 0.025 15.6 3.1 1 23 891 915 891 915 0.92

11 18 0.013 1 10.5 0.7 1 22 935 956 935 959 0.89

12 18 0.0013 0.1 13.7 0.2 1 23 1006 1030 1006 1030 0.93

13 18 2 1.6e+02 3.7 0.1 3 21 1105 1123 1104 1124 0.90

14 18 0.95 76 4.7 3.5 2 19 1214 1231 1213 1236 0.91

15 18 3.3e-05 0.0027 18.7 2.9 1 23 1741 1763 1741 1763 0.99

16 18 0.00088 0.07 14.2 0.3 1 23 1849 1871 1849 1871 0.98

17 18 0.0082 0.66 11.2 0.4 2 23 2009 2031 2008 2031 0.97

18 18 0.37 30 6.0 1.6 2 22 2260 2280 2260 2283 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.00032	0.026	15.6	1.8	2	23	11	33	10	33	0.95
2	18	8e-05	0.0064	17.5	0.7	1	23	65	89	65	89	0.92
3	18	0.012	0.95	10.7	0.4	1	22	137	158	137	161	0.91
4	18	0.0048	0.39	11.9	2.4	1	23	548	571	548	571	0.94
5	18	0.087	7	7.9	0.0	1	23	578	601	578	601	0.95
6	18	0.0081	0.65	11.2	4.1	2	22	656	676	656	679	0.91
7	18	0.93	75	4.7	1.1	1	23	691	716	691	716	0.91
8	18	0.015	1.2	10.4	1.3	1	23	734	756	734	756	0.97
9	18	0.0018	0.14	13.3	0.3	2	23	763	785	762	785	0.96
10	18	0.00031	0.025	15.6	3.1	1	23	891	915	891	915	0.92
11	18	0.013	1	10.5	0.7	1	22	935	956	935	959	0.89
12	18	0.0013	0.1	13.7	0.2	1	23	1006	1030	1006	1030	0.93
13	18	2	1.6e+02	3.7	0.1	3	21	1105	1123	1104	1124	0.90
14	18	0.95	76	4.7	3.5	2	19	1214	1231	1213	1236	0.91
15	18	3.3e-05	0.0027	18.7	2.9	1	23	1741	1763	1741	1763	0.99
16	18	0.00088	0.07	14.2	0.3	1	23	1849	1871	1849	1871	0.98
17	18	0.0082	0.66	11.2	0.4	2	23	2009	2031	2008	2031	0.97
18	18	0.37	30	6.0	1.6	2	22	2260	2280	2260	2283	0.88

Sequence Information

Coding Sequence: ATGCATAGTCGAAACTCCTGTAAAACATTGAAGTGTCCCAAATGTAATTGGCACTACAAATATCAAGAGACGTTAGAAATACACATGAAGGAAAAACATCCGGAAGCTGAAACGAGTTGCATTTATTGCATAGCTGGACAACCTCACCCTCGGCTAGCCCGAGGAGAAACTTACACTTGCGGGTATAAACCATATAGATGTGAAGTCTGTAACTATTCTACAACAACAAAAGGCAATCTTAGCATTCATATGCAATCTGATAAACATCTGAATAATATGCAAGAACTACAGAATGGTGGAAATCCTGGTGAGACTAGCTTACCTCCTGCACCGCAACATACACCACCAGGAGTTCATAAGCCTCCGTTACCGCATCACTCACCACTAGGACAGAAGCCAAAACCTACATTTAGATGCGACGTTTGTAATTATGAGACTAATGTTGCAAGGAACCTAAGGATTCATATGACATCTGAAAAGCATACCCATAACATGCTAGTCttacaacaaaatgtaaaacatatgCAAACATTATCAGCTTTACATCATAGACAACAAAGTCAGCAACAGCTGGAAAGCTTGCTACATTTTCATGGTGGAGATGCACCTCCATCTAACCCTGAAGCAGCGTTAGCCGATATGGCATATAATCAAGCTCTTATGATTCAACTAATGACTGGAGGTCCAGGACCATCACCGCCTGAACTAGGAGCGCATTTAGATGTTGGCTTGAATCCTGAAGCCATGGAACCCCCGCCAGAACCAGCAGACCCTGAGCCAGAACGAACATTCCATTGCTGCATatgcaattgtttttcaacCGATTCCTTGGAAGCCCTAGGACACCATTTAGCGCAAGATCGCACAAAAATTAGAGAGCAAGAAATATTAGCCCTTGTTGCCGGCCATTACGTATGtaaactatgtacatacaagACCAACTTAAAAGCAAACTTTCAACTGCACTGCAAAACCGACAAACATCTACAAAGGCTACAGCACGTGAACCATGTCAAAGAAGGTGGTCCAAGAAATGAGTGGAAGTTGAAATTTTGTGGTGGCGTTGGAACCGGAAGCGCCGGAGTGGGTGGTGTTCAAGTTAGGTGTTGTGCTTGTGACTATTACACAAACTCCGCTCACAAGCTTCAACTGCATGCTGCCGGAGCGAGACATGAAGCAGCAACGCTACTGTTAAGGCACCTAAGAGATTGTGCTTCGCGCATACCACGTGATCGTCCACGTGTATACCGCTGTGCGCTATGCGGCTTCGGTGCCCCTCATCGACTACCTCTTTTGCAACATGTGCGTTCAGTAAAACATTTGCAGATGGAGCAAATTCATCAGCTCCAACGGCGATCTGAAGGCAAAGATCCCACGCCCGATGTTGCTGAGCTATTCCAAGTTATCGCACAGCCTCCTGAGCTACCGAGCCCTTATGATCAACAAGAAAATgATATCAAAGAGCCCATCGATCAAAAACCTGAATTAACACAAGAACAGAAAATGATGCGATTTTTAGAACAACACCAACAACATCAAcagcagcaacaacaacagcagcaacaacatcaacaacaacaatccCATTTATCTCAACATGGATCTGGCGAGAGAGACGACAACCACGAAGCTCAAGGTCAACACAATTGCCCCTATTGCAACTTTACTTGCAGCAGCGAGAGCAAACTACAAATCCATGTTGCATCTGTTCATGGTGACCCTACgagacattttatttgtccACTTTGTCAAGATGCATTTAAAGAAAGACCTGCCCTTGAACGACATGTCATGCAGATACACTCAGTGAACTCAGAAGGTCTACAAAGATTATTGCTTTTAGTAGACCAAAGCCATTGGCTGAATGGAGCAACTCAAGGACAACGAGAGGAATCTCGGCAGGGTGACGATGAACGCGAAATATCTTCTCCTCGTTCCGAAGGAAGTGTTGATGGTGAAACGGAACGTTGCTCTACGTgtaatcggacattccgtaaTGTTGATGAACTGTGTCATCACCAAAATGAATCCGGTCACTTAGAACTGAAACAAACACCCCAAGGGCCGGGATATTTTTGTTGGAAGAAAGGATGCAACCGGTATTTTGACGCAGCTCATGCTCTACAGAACCATTTTAGGGAAGCACACGCAAAAAATTCTATTGCCAACATGTCGGTATCAGAAAAGCATGTTTACAAATACCGTTGTAACCAGTGTAGTTTGgcgtttaaaacaattgaaaagcTACAGCTTCATTCACAGTACCATGTTATTCGTGACGCCACAAAATGCGTATTGTGTGGAAGGAGCTTTAGATCAGTACTAGCTCTTCAAAAGCACGTTGAAACATCTCACTCTGAATTATCTGAGGACGAACTGGCGGCTTTTAAGCGAAGTCTAGCTTCTAATCCGTTATTACAAGCTGGCCAAGGTACAGCGCTTGATGCGGCGACCGCAGATTTGCTGCGGAAGGAAGCTTTAAGAACTCCCGATGATGAACTGGCTGAAATGGAAGACAGAGACTCAAGCGCTACTGCAGCTGATGAATCCGGTCATAATGATGCTGAAAACTCAGATGATTCAATTATATACAAAGATCAACAATTTCTCGAAGATTACTTAAATTCGCAAGCTATGGCGGAAGATTCTTATAATGATCCGAATAGAAAATACAAGTGTCACAGATGTAAAGTGGCATTTACTCGACAATCATATCTAACAGCCCATAACAAAACTCTTTTACATAGAAAAGGGGAGAAATTAACATATCCCATGGAGAAATATCTTGATCCTAACAGACCATTCAAGTGTGACGTGTGCAAAGAATCTTTCACACAAAAGAATATCTTACTGGTCCATTACAATAGTGTTAGCCATTTGCACAAACTGAAACGAGCTATGCAAgaacaacaaaataacaacaatcCTCCTGTGTCACCCGGCGCGGGTACAGCACCATCTAATTTGACTTTAACACCTAAAAGTACATCAAGTGAAGAAGACGACCgaaaaagatataaatgtaatatatgtaaagttGCTTATACACAAGGCAGTACCCTTGACATACATATGAGATCCGTGCTACATCAAACGCGAGCAGGCAAGCTGCAAGAACTCGCCGCGGCCGGCCACGTAGATTTGACACGGCCCCTTGTAGAACAACCGGACAGAAACGACCCcgcaaaaatattacaagacGTTTTGTCGCCGAAAAATACATCCCCTTCGTCTACAAGCAGCGGGGGGCCTCGTTCCTCACCCCCCGCGCGCCCAGGTAGTCCGCGATCCCCGCGCGCAGGTAGCGCCTCGTGCGAGCGGTGCCACGCGTCATTTCCTACTGGGGAGCTACTCGACGCACATCGCGCGACCTCATGTCCGTTTGGCGATGCGCGGGCGCATTCGCCACTAGGTGACGCAGAAGCGGCTGCATTAGACGAGATGGTGGCAAAGGGCAACCCGCCCAAACGCAACTCACAAATGTATAAACAACTACTTGAAACTTTCGGCTTCGATCTAGTTATGcaatacaatgaaaatcaGCGGCGTAAACTCCAAGAAGAACGTGAAATGGTGCGAGTACCAAGTCCGCCACCTCCGCCTCCCGAGGAAAAGCCTCCAGACGGGGAGACGAAATCAACGTGTCAACATTGCAACAAAGAGTTCTCTAGTGTGTTCGTGTTAAAGACCCATTGTGAAGAAGTGCATAAAGACAAAGTTCCACTGGAATTTTTGGAGCAATTTGCGGAACAGTTCAAATCTGAGTATGAAAGGAAATCAGGTGCACCGAACTCACCTCGAGCTGCATCTCCAGCCCCTCAAGGGGACAGGTCGCCATCACCGCGAGGAGACACGAGTGGCAACTTCAATGAGAATGGAAGTGCCTCAGGCGAAGCTCAAGCTGGTGCTCTACTTGCAGCCCAAGTGCAAGAAATGCAAGCAGCATTAAATATGTTGCAATTACAGCAACAGTTGGGACAACTACATCCTATGGTGGCTCAAATGCTATCATTGGGGTTGCCTTTAGGCCTAAACGTGGGAGCCCTGGCAGCTATGAACCTGCAACCTCCGTTGGTGCCGCTCATGCTGCCGCCACCGCCGTTTGACGCGATCGGCTTTCCACACGACGCTCAGCTGAAACAGCAACAGCTCTTACAACAGCAGCAACaaGCAAATGCTGCAGCAGGACAGAAACGAGCTCGAACTCGCATTACGGATGAACAACTAAAGATACTGCGAGCGcattttgatattaacaaCTCACCGAGCGACGAGGCGATTGCAAAAATGGCTAAACAGTCAGGACTAGCTACAAAAGTCATCAAACACTGGTTCcgtaatacattatttaaagaaCGCCAGCGTAATAAAGATTCTccttataattttaacaatccACCGTCGACTACACTCAATCTTGAGGAGTATGAGAAAACTGGTGAAGCTAAAGTTACACCTTTGGATTCGTCAGCAAGTTCGGACGAAGGCAAACCGCCGCctgaaaaaaaagcaaaaattgAAGATACTTCGTATATTGGTCAACAAGAAGTTAAATCCGAACCAAATGATGAACCGACCATGGAAGAAAAATACAACTCTTATGATGATCGACACCAAGAggataaaagttttatttttcctcaGGCCCCATTACAAAGCCCAGCTCTAAATATTCCTGATCTACAACAAAGCATATCGCGTCCACAAACGCCAACACATTTGTCTCTGAACTCATTGATTCAGTCTCAAATTGATTCAATACCAGCCACAAGCATACCTCAACCACCACATCCGTCGATGTTACCGCCGAAGCTAAATCCTAACTTCGCGTCCCCAAACTCCGTGCCCCCGAACGTCCTACCTTTGACCCCAAATCGCAGCCTCAGTCCTGGCAGGGGACCGGCCGATTTCGGACTTTCCGGGGGCAACTCGAACGGATCCAACAGCTCGGGGTCTTCTGGCAAACGCGCCAACAGAACTAGATTCACTGACTATCAGATAAAAGTTCTACAAGAGTTTTTTGAGAATAACGCATATCCGAAAGATGATGACTTGGAGTATCTCTCTAAATTACTAGGTTTAAGTCCGAGAGTAATAGTAGTATGGTTTCAAAACGCTCGGCAAAAGGCTAGAAAAGTGTATGAAAACCAACCAGCCGCTGAACCACCAGCCGGTGCTACTGACGATGCTAACAGATTTCAACGCACGCCCGGTCTTAATTACCAATGCAAGAAATGCCAACTAGTATTTCAACGGTACTATGAATTAATAAGACATCAGAAAACGCACTGTTTCAAAGAAGAAGATGCTAAAAGATCGGCACAAGCGCAAGCAGCTGCTGCCCAAGTGGCAGCAACACTAAGCAGTGAAGACTCAAATTCTAGTACAGTAGAGCATCATCCACCACATGTACCAGTGTCACCCGCTCCTCCTCGCACGCCAACACCTGCTGCCCCAAATTATCCGGTCTCTCCTGCACCACAAACTCCGCACACGCCAGTTACTCCGCTGTCGCATCAACCACGTGAAGAAAAAGACGGTAATTTTCAATGTGATAAATGCAACCTAGTTTTCCCACGGTTTGATTTGTGGAGGGAACATCAATTAGTTCACATAATGAACCCTAATTTATTTCCGACATATCCACCGGATTCCCCTTTTGGAATTTTGCAACAGCATGCCcaattacaacaattaaaCGCATCTCTAACGAATGAAGAAGTACGTCACCCTTTAGTGGCAGCATTAAATCAGCAAGTTGCAAAACGAAAATTTGATGAGTTTGAAGAAGTGGACACCGGAGAACAACCAAAAGACAAACGATTAAGAACAACTATTTTACCTGAACAACTGGACTATCTTTACCAAAAGTATCAAATAGAATCTAACCCATCACGAAAAATGCTAGAGAATATTGCACGTGAagttggtttaaaaaaaagagtgGTACAAGTTTGGTTTCAAAACACACGAGCACGTGAAAGAAAGGGGCAATTTCGTGCGCATGCGCAAGTCATAAATAAACGATGTCCTTTTTGTCCAGCTTTGTTCAAGGTAAAGAGTGCTTTAGAGAGTCATCTTAGTACTAAACATGCGGATCAGTGTGCACGAGGAGAAATCAATGTGGATGCCTTACCGGATGAAGAACTCAGTACAGAATCTACACCAAGTTTTGGTTCCCAACAAAGTGATCGACAGCAAAATTTTTCCCAAGCGGGGGCTCCCATGTTGCCCCCTATTTTCCCGCCTTTTCACTCAGACATGGAGAAATTTATCAAGCAGTACAGTGAGGAATCTATGAAGAGATATGTAAGCGAACTGCAAGCGCATGCTGCTTCCCAACAAAACGGTGGCAGCAATGAATCTTCGGAAAGACGGCCAGAACATGGAAAATCGGAAATACCATTAGATCTTAGCAAACCAGTCGATTTATCACGACCGGGATCGGATGCAGATGAACGGTCAGATACTGCGTCGGAAACTATGGAGTTCTATGAGGAAGATGAGCCAACATCGCCTGTGGCCGGCCAACAGCAAACGTCGAGGCCGCCTGGTAAACGTTTTCGAACTCAAATGTCTTCTCTCCAAGTGAAGATTATGAAATCGTTGTTTAGCGATTATAAAACGCCGACAATGGCGGAGTGTGAGGCGCTCGGACGAGAGATTGGACTACCTAAGCGAGTGGTACAAGTGTGGTTCCAAAATGCACGTgccaaagaaaaaaaagcgCGGCTGGCGGCCGGCTTGTCGGAGGTGTCGGATGCACCACCACCGGAGGAGTGTCGCGTCTGTGACTTCAAGTACAGTCATAAATATTCCGTGCAAGACCACGTGTTCACGCGCGGTCACATCGCAACGGTTCGTGCGCGTCTAGAAAGCGGCGCGGGCGGGTGTGAAGACAGCACACTCGCGCTCATGCAGATGGCTGCACGGCTAGAAGGAGGGATCGGCAGCGAAATACACAGCGCGTTCCTGCGGCCACAGCTCGCCGGCAACGGTGAGTGCACTACTTGA
Protein Sequence: MHSRNSCKTLKCPKCNWHYKYQETLEIHMKEKHPEAETSCIYCIAGQPHPRLARGETYTCGYKPYRCEVCNYSTTTKGNLSIHMQSDKHLNNMQELQNGGNPGETSLPPAPQHTPPGVHKPPLPHHSPLGQKPKPTFRCDVCNYETNVARNLRIHMTSEKHTHNMLVLQQNVKHMQTLSALHHRQQSQQQLESLLHFHGGDAPPSNPEAALADMAYNQALMIQLMTGGPGPSPPELGAHLDVGLNPEAMEPPPEPADPEPERTFHCCICNCFSTDSLEALGHHLAQDRTKIREQEILALVAGHYVCKLCTYKTNLKANFQLHCKTDKHLQRLQHVNHVKEGGPRNEWKLKFCGGVGTGSAGVGGVQVRCCACDYYTNSAHKLQLHAAGARHEAATLLLRHLRDCASRIPRDRPRVYRCALCGFGAPHRLPLLQHVRSVKHLQMEQIHQLQRRSEGKDPTPDVAELFQVIAQPPELPSPYDQQENDIKEPIDQKPELTQEQKMMRFLEQHQQHQQQQQQQQQQHQQQQSHLSQHGSGERDDNHEAQGQHNCPYCNFTCSSESKLQIHVASVHGDPTRHFICPLCQDAFKERPALERHVMQIHSVNSEGLQRLLLLVDQSHWLNGATQGQREESRQGDDEREISSPRSEGSVDGETERCSTCNRTFRNVDELCHHQNESGHLELKQTPQGPGYFCWKKGCNRYFDAAHALQNHFREAHAKNSIANMSVSEKHVYKYRCNQCSLAFKTIEKLQLHSQYHVIRDATKCVLCGRSFRSVLALQKHVETSHSELSEDELAAFKRSLASNPLLQAGQGTALDAATADLLRKEALRTPDDELAEMEDRDSSATAADESGHNDAENSDDSIIYKDQQFLEDYLNSQAMAEDSYNDPNRKYKCHRCKVAFTRQSYLTAHNKTLLHRKGEKLTYPMEKYLDPNRPFKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQNNNNPPVSPGAGTAPSNLTLTPKSTSSEEDDRKRYKCNICKVAYTQGSTLDIHMRSVLHQTRAGKLQELAAAGHVDLTRPLVEQPDRNDPAKILQDVLSPKNTSPSSTSSGGPRSSPPARPGSPRSPRAGSASCERCHASFPTGELLDAHRATSCPFGDARAHSPLGDAEAAALDEMVAKGNPPKRNSQMYKQLLETFGFDLVMQYNENQRRKLQEEREMVRVPSPPPPPPEEKPPDGETKSTCQHCNKEFSSVFVLKTHCEEVHKDKVPLEFLEQFAEQFKSEYERKSGAPNSPRAASPAPQGDRSPSPRGDTSGNFNENGSASGEAQAGALLAAQVQEMQAALNMLQLQQQLGQLHPMVAQMLSLGLPLGLNVGALAAMNLQPPLVPLMLPPPPFDAIGFPHDAQLKQQQLLQQQQQANAAAGQKRARTRITDEQLKILRAHFDINNSPSDEAIAKMAKQSGLATKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVTPLDSSASSDEGKPPPEKKAKIEDTSYIGQQEVKSEPNDEPTMEEKYNSYDDRHQEDKSFIFPQAPLQSPALNIPDLQQSISRPQTPTHLSLNSLIQSQIDSIPATSIPQPPHPSMLPPKLNPNFASPNSVPPNVLPLTPNRSLSPGRGPADFGLSGGNSNGSNSSGSSGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLGLSPRVIVVWFQNARQKARKVYENQPAAEPPAGATDDANRFQRTPGLNYQCKKCQLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQVAATLSSEDSNSSTVEHHPPHVPVSPAPPRTPTPAAPNYPVSPAPQTPHTPVTPLSHQPREEKDGNFQCDKCNLVFPRFDLWREHQLVHIMNPNLFPTYPPDSPFGILQQHAQLQQLNASLTNEEVRHPLVAALNQQVAKRKFDEFEEVDTGEQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLSTKHADQCARGEINVDALPDEELSTESTPSFGSQQSDRQQNFSQAGAPMLPPIFPPFHSDMEKFIKQYSEESMKRYVSELQAHAASQQNGGSNESSERRPEHGKSEIPLDLSKPVDLSRPGSDADERSDTASETMEFYEEDEPTSPVAGQQQTSRPPGKRFRTQMSSLQVKIMKSLFSDYKTPTMAECEALGREIGLPKRVVQVWFQNARAKEKKARLAAGLSEVSDAPPPEECRVCDFKYSHKYSVQDHVFTRGHIATVRARLESGAGGCEDSTLALMQMAARLEGGIGSEIHSAFLRPQLAGNGECTT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00213858;
90% Identity: iTF_00006114;
80% Identity: iTF_00025099;