Basic Information

Insect: Agapetus fuscipes
Gene Symbol: ZFHX3
Assembly: GCA_951799405.1
Location: OX637344.1:2277658-2286953[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.3 1.5e+02 3.6 1.8 1 21 38 58 38 61 0.88

2 15 0.077 5.2 8.2 0.0 1 23 71 94 71 94 0.92

3 15 0.062 4.2 8.5 1.9 2 22 161 181 161 184 0.90

4 15 0.57 39 5.5 0.4 3 23 198 221 196 221 0.87

5 15 0.013 0.87 10.7 1.7 1 23 239 261 239 261 0.97

6 15 0.0083 0.57 11.3 1.1 2 23 268 290 267 290 0.96

7 15 0.00074 0.05 14.6 3.9 1 23 398 422 398 422 0.92

8 15 0.012 0.82 10.7 0.7 1 22 442 463 442 466 0.89

9 15 0.0012 0.082 13.9 0.2 1 23 517 541 517 541 0.93

10 15 0.28 19 6.5 0.1 3 23 620 640 619 640 0.96

11 15 0.48 33 5.7 2.6 2 19 746 763 745 768 0.91

12 15 3.1e-05 0.0021 18.9 2.9 1 23 1370 1392 1370 1392 0.99

13 15 0.0013 0.088 13.8 0.3 1 23 1502 1524 1502 1524 0.98

14 15 0.01 0.69 11.0 0.4 2 23 1666 1688 1665 1688 0.96

15 15 0.24 17 6.6 2.4 3 22 1943 1962 1941 1965 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.3	1.5e+02	3.6	1.8	1	21	38	58	38	61	0.88
2	15	0.077	5.2	8.2	0.0	1	23	71	94	71	94	0.92
3	15	0.062	4.2	8.5	1.9	2	22	161	181	161	184	0.90
4	15	0.57	39	5.5	0.4	3	23	198	221	196	221	0.87
5	15	0.013	0.87	10.7	1.7	1	23	239	261	239	261	0.97
6	15	0.0083	0.57	11.3	1.1	2	23	268	290	267	290	0.96
7	15	0.00074	0.05	14.6	3.9	1	23	398	422	398	422	0.92
8	15	0.012	0.82	10.7	0.7	1	22	442	463	442	466	0.89
9	15	0.0012	0.082	13.9	0.2	1	23	517	541	517	541	0.93
10	15	0.28	19	6.5	0.1	3	23	620	640	619	640	0.96
11	15	0.48	33	5.7	2.6	2	19	746	763	745	768	0.91
12	15	3.1e-05	0.0021	18.9	2.9	1	23	1370	1392	1370	1392	0.99
13	15	0.0013	0.088	13.8	0.3	1	23	1502	1524	1502	1524	0.98
14	15	0.01	0.69	11.0	0.4	2	23	1666	1688	1665	1688	0.96
15	15	0.24	17	6.6	2.4	3	22	1943	1962	1941	1965	0.89

Sequence Information

Coding Sequence: ATGCTCAAATTTCTGGAACAACAGCAACACATTCACCAACAGATGCAACTGCAAATGCAACAACAGCAAATGATGCAACAGCAGGAGGAGTCACAGAACGAACAGCAAACGCATTCGTGTCCGTTCTGCAACTTCACCTGCGACTCTGAGATGAGACTGCAAGCTCATGTCGTAGCGCAACACAGCGCACCGACTCCCACCCCGCCAGCATTCTTATGTCCACTGTGCCAAGATGGCTTCAGAGATAGACCAGCACTTGAAAGACACGTCATGCAAATACACTCAGTCAACTCGGAAGGTCTCCAGCGACTGTTGATGCTTGTAGATCAAAGCCACTGGCTGAACAGTGCGAGACTCGTTAGTCCTGACTCAGTCGCAAGCAGCAAAGATTCAGCGAATAAGAACGACTCGGCAAACATGGAAGAGGAAAGAGAAATATTGTCACCGCAGAGTGAAGAAAACTCAGAGTACGAAGCTGAACGTTGTACGACTTGCTTGAAGAACTTTAGAAACATCGATGAACTCTGTATACACCAGAATGAAACAGGACACCTTGAGCTGAAGCAGACACCGCAAGGTCCTGGTTACCTTTGCTGGAAGAAGGGATGTAATCAGTATTTCAATAATGCACAAGCTCTGCAGATGCATTTCAAAGAAATTCATGCCAAGAATTCCATTTCTAATATGTCAGTGTCGGAGAAACACGTTTACAAATACCGTTGCAACCAATGCAGTTTGGCTTTCAAGACCATGGAAAAGTTACAATTGCATTCCCAATACCACATGATAAGAGACGCCACTAAGTGTGTCCTGTGTGGAAGGAGCTTCAGGTCAATCTTGGCTCTACACAAGCACGTGGAAACATCTCATTCTGAGCTTACTGAAGAAGAAGTGGCCGCGTTCAAACAAAGTCTGATGAATAATCCTCTTCTGTTGGCTGGACTTCAAGGACAAGTCCTGGACAGCTCCACCAATGAACTTCTGAAGAAAGAATCTTTGAAACTGACTGAAGAAGAAATGATGGAGCTCGAAGAAAGCAAAGAAATGAACAACATGAGCAATGAGGATGGAAATCAGGTCGACGGAGAAAATTCCGATGACTCAATTGTTTACAAAGAACAACAATTTTTGGAAGATTATTTGAATTCACAAGCCATGGCTGAAGATTCTTACAACGATCCAAACAGGAAGTACAAATGTCACCGCTGCAAGGTCGCGTTCACGAGACAATCCTACTTGACCTCCCACAACAAGACTCTGCTGCATCGGAAGGGAGAGAAATTAACATACCCGATGGAGAAGTACTTGGACCCCAATCGACCTTTCAAGTGTGATGTATGCAAAGAGTCGTTCACGCAAAAGAACATCTTGCTCGTTCATTACAACAGCGTCAGCCATTTGCATAAACTAAAGCGAGCGATGCAGGAGcaacaaaacaacaacaacgTTCCTCCCAGTTCACCCGGTGTCGGGAACGCTACGTTGAATTCGTCGAATTTGGCGCTTACGCCCAAAAGTACATCTAGCGAGGAAGACGATAAAAAGCGTtataaatgtaatatttgtaaAGTCGCATACACACAGGGAAGCACTCTAGACATCCACATGCGATCAGTTTTGCATCAGACGCGCGCGAGTAAGCTACAGGACCTCGCGATATCGGGACAGATTGACTTATCGAAGCCGCTGATCGAGCAGCCAGACATGCCCAAGGGCCAAGACCCGGCGAAGATCTTTCAAGACATGCTGTCGCCTAAGAATACATCCCCTTCGTCTTCGTCTAGCGGCGGGGTGCGCGGGGCTTCCCCTGGCGGCGCGGGGCCCCCTTCCCCCTCGCAGGCACCCCTAGGCGTGGCCTGCAATAGGTGTCACGCGCCCCTCGCCTCGCAGGAACAGTTGCTCGCACACCAGGCACTGCACTGTCTGTTCGGTCCGGGGAGCGCCGCTCTAGCAGGACTAGCGCAACTAGAAGCACAAGACAGATCTCCAGGCGCAGATGACATGGGCGCCAAACTCAACCAGCCCAAGAGGACCAACTCCCAGATCTACAAGCACCTCCTCGAGAGCTTCGGCTTCGATCTGGTGATGCAATACAATGAAAACCATCAGAGGAGACAGCTGAGCATGAAGAATGCCGAAAAGGAGATGAAGCCTCCCACCCCTCCCGCTCCTCCTGAACCGGAACCCGAAGAGGAACCCGAACCGGTTATCCCGCTGCCGGAAATCAAGAAATCTACgtgtcaacattgtaataaaGAGTTTTCTAGTGTTTGGGTGCTGAAGACCCACTGTGAAGAAGTGCATAAAGATAAAGTGCCGCTCGAGTTTTTGGAGCAGTTTGCTGAACAGTTCAAAAGtgaatacgaaaaaaaaatagtggtaGTGACAGCGGCAACGTCCTCCACAGTCACAGCCACAAGCCCGCGAGTGACGTCACCTAATGCTGAAATAACCACGAGTGTAGTGTCCACGACAGCAACTCCTACAACGCCTATACAATCCGCACAGCAACATCATCAGCAGCATCAGCATCAATTGCACCAACAGCAGCAACAGCAACAGCTGCAGCATCATCAAGAACAAATGGAAAACGAAGAAAGGGAACAGAGAAACAGCATCAACCAGAGGACCAACGATTTGACCAACAACATTGACTCTGATCGACCGAGTTCTCGGAACAGCAACCACACTCCTGCCCTCCAGCTCGCTCAGCACATGAGCGAAGTCCAAGCTGCCCTTGGGGTGATGCAACTGCAGCAACAGTTGGGGCAGTTGCACCCTGTGGTCGCCCAGATGCTGTCCATGGGTCTGCCTCTTGGACTGAACGTCGGAGCCTTGGCAGCGATGAACCTCCAGCCTCCTTTGGTGCCAATGATGATGCCTCCGCCACCGTTTGACCAGATGCCACCATATTCTCCGCATCCTCAGGATAACCAGGCCATGCTGAAACAACAACACGCCATGATGCAACAGCATCAACAAGCAAATGCCGCAGCAGCCAACCAAAAAAGGGCGCGAACACGCATCACAGACGACCAGCTGAAAATTCTGCGCGCTCACTTTGACATCAACAACTCTCCAAGCGAAGATGCTATCCATGAGATGGCAGGACAATCTGGTCTACCACCCAAGGTCATCAAGCATTGGTTCAGAAACACGCTGTTCAAAGAGCGACAAAGAAACAAAGATTCGCCATACAACTTTAACAATCCACCATCAACCACACTCAACTTGGAAGAATATGAAAAGACAGGTGAGACCAAAGTAACACCCTTGAACTCATCTGCAAGCTCTGACGAAGGAAAACCTCCACCAGAGAAAAGGCCGAAGCCGTCTCCTGCACCGACGCCACCGACGCCCTTTCACCAACCTGAAAACCTGGTAAAAATGGAACCGCACGATGATTTAAACTCTGAAGAGATAAATAAGTACAATTCGTACGATAACAAACATCAGGAAgataaaatgtataattttcCGATGGGATTACCACCACAGAGTCCAGTTCCAAGTTTATCAGGATCTGAGCATTTACCTCAAAACATGTCGAGACCGACGACTCCGAATCACATGTCTTTGAGCTCGATTATACAATCACAGCTGGAGTCCATCCCGGCTTCAGCGATCCCTCAAGTGCAGCAGATGTCTGGCAACAATCACCACCCATCAATGCTTCCGCCAAAACTAACACCCCAGAACTTCGCGTCCCCAAACAATTTGCCCCCGAATGTCTTACCCATGACCCCAAACAGAAGTTTAAGCCCTGGTCGAGGTTTAAATGAATTTGGACTTTCCGGGGGCAATTCCAATGGGTCTAATAGCTCAGGGGGGTCATCCGGCAAACGAGCCAACAGAACACGATTCACCGACTACCAAATCAAAGTCTTGCAAGAGTTTTTTGAGAATAATGCATATCCGAAAGACGACGACCTTGAATATCTATCAAAATTGTTAGGGTTGAGCCCTAGAGTGATTGTTGTTTGGTTTCAGAACGCAAGACAGAAAGCCAGAAAGGTTTATGAGAATCAGCCAGCAGTAGAACAGCCGCTGCCTGGGATTCCCGATGAACCTGGAGCTAACCGGTTTCAAAGAACTCCAGGCTTGAACTATCAGTGCAAGAAATGCCAGCTTGTATTCCAACGTTACTACGAATTAATTAGGCATCAAAAGACACATTGCTTCAAAGAAGAAGATGCTAAACGGTCAGCACAGGCCCAAGCTGCTGCTGCACAAGTTGCAGCAACTTTAAGCAGTGAAGATTCCAACTCCAGTACAACAACCAGTGAACAGCATCACAACATGGGACAACCAATGCAGCAGCAACATAGAGAGCTGCAACCTCCTCAACATCACAGTGTTCCAGCCAGCCCAGTGATGAGCATGCCTCAACAACCAATCACTCCAACACCTTCCAGTTCTAACTATCCTTTATCACCAGTGACTACACCAACTCCCAGTGAAAGAGGAGGCCAAGATAGAGATCGCGAACAGAAAGAAGGAACATTTCAATGTGACAAATGTAACCTTGTCTTCCCTCGCTTTGAACTTTGGCGCGAACATCAACTAGTTCATATCATGAATCCGAATTTATTTCCAACATATCCTCCGGATTCCCCTTTTGGGATACTCCAGCAACACGCTCAGCTACAGCAGCTGAATGCCTCTTTGGGTGGCGGAGATCCCAGCGGAGTACCACATCCGCTTATGTCAATGTTGAATAACCAGATGAACAAACGGAAGTTTGATGACTTCGAAGTAGAAGTTGACTCTGGTGATCAACCTAAAGACAAAAGATTGCGAACGACAATTTTACCAGAACAATTGGATTATTTATACCAGAAATATCAAATTGAATCGAATCCTTCGAGGAAAATGTTGGAAAACATTGCTAGAGAAGTCGGTCTTAAAAAGAGAGTGGTTCAAGTATGGTTTCAAAATACAAGAGCCAGAGAAAGAAAAGGCCAATTCAGGGCGCACGCTCAAGTCATCAATAAACGTTGCCCCTTTTGTCCAGCCCTATTCAAAGTGAAGAGCGCATTGGAAAGCCATCTCACCACCAAACACGCAGACCAGTGCTCTAGAGGAGAGATCAACATTGATGCTCTGCCTGATGAAGAATTAAGTATGGAATCATCACCGAGTTTTGGATCGCAGCAAGGGGACAAACCAGGAAATTTTCCCCAAGGGGGGGCAAATATGATGCCCCCCTTATTCCCACCTTTTCATCCAGATATGGAGAAATTTATTAAGCAATACAACGATGAGTCAATGAAGAGATACATAACAGAACTCCAAGCCCACGCGGCAGCTCAGCAAAATGGAGGAGAACCAAAGGAGTCAGGCAGACCAGAAGGCGAGATCCCTTTAGACCTCAGCAAACCAGTTGATTTATCGCGGCCGATGAAAGTGAACATGGATGATGAACGTGGAGTGTGCGAGCAAGGCCCTGCCACTGATCTCAGTGAACGATCTCTCTGCGACGAGCGCTCGGACACCATGTCGGAGACCACAGAGTTCTACGATGACGAGAGCAATCCCACATCTCCCAGCTCCACGCAAAGCAACAACAGGCACAACTCGTCAGCAGCAAGCAAACGATTCCGCACTCAGATGTCATCATTACAAGTCAAAATCATGAAGTCATTGTTTCACGACTACAAAACCCCCACCATGGCTGAGTGCGAGATGCTCGGCAGAGAGATCGGACTTCCAAAGCGAGTGGTGCAAGTTTGGTTTCAAAACGCGAGAGCCAAAGAGAAGAAACACAAGCTGGCGCTGCAGAAGTCATCAGGAGTGCCTGAAGCTGAGCCCAGAGGACCAGACGATTGCAAATATTGCCAGTTCAAGTACAGCCACAAGTATTCAGTGCAAGATCACGTGTTCACCAAGGGGCATATTGCAGCCGTCAGAGCTTCTCTGGAAGGCTTGGCCCAGCAGCAAGCCAACAACCAGCGCGATGATGGAGTGGTGAACTCTTCGCAGAACCCTGGACCTCTCGCCTTGCTGATGGCCGCCAGGCTGGAGGGGAGGGATGACGAGCTCCTGAGGAGGCTGTGCGCCCCAGCCGCCCCCGCCCCGCCCCCCACGCGCCCCCTGATGCCCGCCTACCCTCCCAACGGTGAGTGCCCCATTTAA
Protein Sequence: MLKFLEQQQHIHQQMQLQMQQQQMMQQQEESQNEQQTHSCPFCNFTCDSEMRLQAHVVAQHSAPTPTPPAFLCPLCQDGFRDRPALERHVMQIHSVNSEGLQRLLMLVDQSHWLNSARLVSPDSVASSKDSANKNDSANMEEEREILSPQSEENSEYEAERCTTCLKNFRNIDELCIHQNETGHLELKQTPQGPGYLCWKKGCNQYFNNAQALQMHFKEIHAKNSISNMSVSEKHVYKYRCNQCSLAFKTMEKLQLHSQYHMIRDATKCVLCGRSFRSILALHKHVETSHSELTEEEVAAFKQSLMNNPLLLAGLQGQVLDSSTNELLKKESLKLTEEEMMELEESKEMNNMSNEDGNQVDGENSDDSIVYKEQQFLEDYLNSQAMAEDSYNDPNRKYKCHRCKVAFTRQSYLTSHNKTLLHRKGEKLTYPMEKYLDPNRPFKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQNNNNVPPSSPGVGNATLNSSNLALTPKSTSSEEDDKKRYKCNICKVAYTQGSTLDIHMRSVLHQTRASKLQDLAISGQIDLSKPLIEQPDMPKGQDPAKIFQDMLSPKNTSPSSSSSGGVRGASPGGAGPPSPSQAPLGVACNRCHAPLASQEQLLAHQALHCLFGPGSAALAGLAQLEAQDRSPGADDMGAKLNQPKRTNSQIYKHLLESFGFDLVMQYNENHQRRQLSMKNAEKEMKPPTPPAPPEPEPEEEPEPVIPLPEIKKSTCQHCNKEFSSVWVLKTHCEEVHKDKVPLEFLEQFAEQFKSEYEKKIVVVTAATSSTVTATSPRVTSPNAEITTSVVSTTATPTTPIQSAQQHHQQHQHQLHQQQQQQQLQHHQEQMENEEREQRNSINQRTNDLTNNIDSDRPSSRNSNHTPALQLAQHMSEVQAALGVMQLQQQLGQLHPVVAQMLSMGLPLGLNVGALAAMNLQPPLVPMMMPPPPFDQMPPYSPHPQDNQAMLKQQHAMMQQHQQANAAAANQKRARTRITDDQLKILRAHFDINNSPSEDAIHEMAGQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGETKVTPLNSSASSDEGKPPPEKRPKPSPAPTPPTPFHQPENLVKMEPHDDLNSEEINKYNSYDNKHQEDKMYNFPMGLPPQSPVPSLSGSEHLPQNMSRPTTPNHMSLSSIIQSQLESIPASAIPQVQQMSGNNHHPSMLPPKLTPQNFASPNNLPPNVLPMTPNRSLSPGRGLNEFGLSGGNSNGSNSSGGSSGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLGLSPRVIVVWFQNARQKARKVYENQPAVEQPLPGIPDEPGANRFQRTPGLNYQCKKCQLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQVAATLSSEDSNSSTTTSEQHHNMGQPMQQQHRELQPPQHHSVPASPVMSMPQQPITPTPSSSNYPLSPVTTPTPSERGGQDRDREQKEGTFQCDKCNLVFPRFELWREHQLVHIMNPNLFPTYPPDSPFGILQQHAQLQQLNASLGGGDPSGVPHPLMSMLNNQMNKRKFDDFEVEVDSGDQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLTTKHADQCSRGEINIDALPDEELSMESSPSFGSQQGDKPGNFPQGGANMMPPLFPPFHPDMEKFIKQYNDESMKRYITELQAHAAAQQNGGEPKESGRPEGEIPLDLSKPVDLSRPMKVNMDDERGVCEQGPATDLSERSLCDERSDTMSETTEFYDDESNPTSPSSTQSNNRHNSSAASKRFRTQMSSLQVKIMKSLFHDYKTPTMAECEMLGREIGLPKRVVQVWFQNARAKEKKHKLALQKSSGVPEAEPRGPDDCKYCQFKYSHKYSVQDHVFTKGHIAAVRASLEGLAQQQANNQRDDGVVNSSQNPGPLALLMAARLEGRDDELLRRLCAPAAPAPPPTRPLMPAYPPNGECPI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00178985;
90% Identity: iTF_00023530;
80% Identity: iTF_00023530;