Basic Information

Gene Symbol
vUbi
Assembly
GCA_951799405.1
Location
OX637349.1:7188039-7202902[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.00035 0.024 15.6 1.5 3 23 365 385 364 385 0.98
2 11 0.018 1.2 10.2 0.2 1 23 391 414 391 414 0.94
3 11 7 4.8e+02 2.0 0.4 1 23 452 474 452 474 0.84
4 11 0.14 9.8 7.4 0.4 1 21 491 511 491 512 0.93
5 11 0.48 33 5.7 0.2 3 21 572 590 570 591 0.93
6 11 0.00067 0.046 14.7 1.1 2 23 602 623 601 623 0.97
7 11 1.8e-07 1.3e-05 25.9 0.8 1 23 630 652 630 652 0.98
8 11 0.013 0.87 10.7 0.3 1 23 658 680 658 680 0.97
9 11 0.00057 0.038 14.9 0.2 1 23 686 708 686 708 0.97
10 11 0.00018 0.012 16.5 0.3 1 23 714 736 714 736 0.98
11 11 2.6e-05 0.0018 19.1 4.6 1 23 742 765 742 765 0.98

Sequence Information

Coding Sequence
ATGAAATTGACGCTTAAGAATTCCGATGGTAATGCGATCACGGTGAGCATCTTCCCGCAGGACACTCTGGAGGACTTGAGGACGAGGATCAACCAGGATTATGGATTCCCTCTAGATTTGCAAAACTTGGTTTTCAAGGGAAACAAACTCTCCGACTCGCAAAAAATCTACGATTGCATTTCAAATAGTTATCCAGAAATTGATGATATTCAACCCAAATCATCCAAGCTGTGTCGCCTTTGTGCCAAGCCGTTTGCCGACATGTTGGACATTTTCCCTGCCAACGGGGAAGACAACATGACGGGTTTATGGCAAGGCCCGCCAACCTTAGCAACAGCCATCAACACTTGTTTACCCGTTACCGTGACAACAACGGATTTATTACCAAAAAAGATTTGTCATGTGTGCATAGTGCAGCTGAAGGAATGTTCATTGTTTCACCAGTCCAGCTTAAAAGCGGAATCAAAGCTGATCGATTTGTGCAAAAGTGAAAAGGTTTCGAGTTATGCTGTTAAACAAAATATCCCGCAGATGTTTGAGAATAAAGAAGACGGTCAAACAGATTTGACAGTGGATTCACAGTTAATTATCGCCGATCACGGGATACAAATCTCAAAGTTTAACAATACTGATGTGGCTTACTCCGATTTGATTGCCAACTATGTGAATTGTAATTTAATTGATGCCATCGATCTGACCAACGAGACGGGTGGAAATGATTTGAAATTGGAAATGGTGAACAGCGAGGCTCAAAGCGGGATGCTCACAGAAGCTGGGAATATTATTGTGGTTTGCCAGGATGACGAGAATACTAACTGCTACGAGTTTAACAGTTTCACAGGACTGCCAACATTCTTAAAAaaATGTTTCAAGTCTGACTCCAGTCCATCTACCATGGATGAAGCTGTAAAGGATGACATTCTAAACCAGATGGAAGAGAAATCTGCGGAGTTTCCTGATGATGAAATACCACAGAACGAAACACCGACGGAAGAATGGCTGGAGGAAGAAAACAAATTTAAGAATAGTCAACAGATTACCAATGTGATAGACGAGAATCTGGACCAGCCGTACATTCGTATCCTGCAGCTGTGCAAGTGGTGTTCGGAAGTGTTCTCAACACAAGACGAGCTGTTCCATCACTCGCTGACTCACAGCGACAACTCAACGTACAACTGCGCCTTTTGTGACCAATCTTTTCCCGGCTTAAAGGAATACACCAACCATGTGCAAGCAGACCATCCCGATAACCAATATGTGGACAATCCCATCACGAGTTCTGTTAAAGTGATCAAGAAGAAGAGTGATCGTCCGCAGAAGAGTGGTCGCAGGTTCCAGCCGGTGCAGATGTGCCACAGCTGCCAAGTCTGCTACCAGGTCTTCCTGACTGCCGAGGAAGCACTTCTTCATTCAAAGGTCCACCCCGTGATGTGTGAAGCGGCATGGCAGTGCGTGAACCTGCGGCGCGTGTACGCCTGCGCCTTCTGCAGTGCCCACTTTGCGCGCCCCCGACACCTGCTGGGCCACAGGCAGGACTGCTGCGGAGACATCAGCACAGACTTTGATGTTGTAGCACATTTGGAAAAAGGTGTCGGCTGGTCCATTCCTCGCGTGCTCATCGGAAAGAACAGCTCTCACAAGGCCACGGCTCAGCCACGGCTTAAAGACCACAACGAGCTGAAGGAGACAGCGGGGAAGAGTAAACTGTGGAACTGTGGCTCGTGTAACACGCTGTTTGAAAGTGCCAGGGAACTGTACAAGCACAAGCGAGGCGAGGACATGACTATTGAAGGAGCAGCTTCTGTCTGCGAGCAGTGTGGCAACGTGTTTGGGAGTAAATGTGCGCTTCagacacacctcaagagtcatGAGAAACCACAAACAGGTTACCCTTGTGAGACATGCGGCCGCCGCTTTAACCAGTCCGGCCACCTGGCAATACACATGAGGATGCACACAGGGGAGCGGCCTTATCCATGCGACCTGTGCTCCAAAGCATTCAAAGTCAAAGTAGAGAGAGATGATCACCGTCGCCTGCACACAGGAGAGCGCCCCTTTGCATGTCCCGTTTGCAAGAAAACATTCACAGCTCTGGCGAGGCTACGAGAACACTCCAGGATACACTCCGACAAAAAGCCCTACAAGTGCAACATCTGCTTGGCATCATTCCGGCGTCCATACGCCAAGACTGTGCACATGCTCATCCACACGGGGGAAAAGCCTCACAAGTGCTCTCACTGTGGGACCACATTCAGACGAACTGGAGACATGTGGAAGCATGTGAGAACCATGCACGGGAAATGA
Protein Sequence
MKLTLKNSDGNAITVSIFPQDTLEDLRTRINQDYGFPLDLQNLVFKGNKLSDSQKIYDCISNSYPEIDDIQPKSSKLCRLCAKPFADMLDIFPANGEDNMTGLWQGPPTLATAINTCLPVTVTTTDLLPKKICHVCIVQLKECSLFHQSSLKAESKLIDLCKSEKVSSYAVKQNIPQMFENKEDGQTDLTVDSQLIIADHGIQISKFNNTDVAYSDLIANYVNCNLIDAIDLTNETGGNDLKLEMVNSEAQSGMLTEAGNIIVVCQDDENTNCYEFNSFTGLPTFLKKCFKSDSSPSTMDEAVKDDILNQMEEKSAEFPDDEIPQNETPTEEWLEEENKFKNSQQITNVIDENLDQPYIRILQLCKWCSEVFSTQDELFHHSLTHSDNSTYNCAFCDQSFPGLKEYTNHVQADHPDNQYVDNPITSSVKVIKKKSDRPQKSGRRFQPVQMCHSCQVCYQVFLTAEEALLHSKVHPVMCEAAWQCVNLRRVYACAFCSAHFARPRHLLGHRQDCCGDISTDFDVVAHLEKGVGWSIPRVLIGKNSSHKATAQPRLKDHNELKETAGKSKLWNCGSCNTLFESARELYKHKRGEDMTIEGAASVCEQCGNVFGSKCALQTHLKSHEKPQTGYPCETCGRRFNQSGHLAIHMRMHTGERPYPCDLCSKAFKVKVERDDHRRLHTGERPFACPVCKKTFTALARLREHSRIHSDKKPYKCNICLASFRRPYAKTVHMLIHTGEKPHKCSHCGTTFRRTGDMWKHVRTMHGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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