Basic Information

Insect: Aenictocupidus jacobsonorum
Gene Symbol: zfh1
Assembly: GCA_010014765.1
Location: JAAAKC010000776.1:11610165-11615383[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0027 0.31 11.5 1.1 2 23 53 75 52 75 0.93

2 8 0.17 19 5.9 0.4 8 23 110 125 102 125 0.80

3 8 3.9e-06 0.00046 20.4 0.6 2 23 132 153 131 153 0.97

4 8 7.4e-07 8.7e-05 22.7 5.9 1 23 162 184 162 184 0.99

5 8 3.1e-05 0.0037 17.6 1.0 1 21 190 210 190 211 0.95

6 8 6.8e-06 0.0008 19.7 0.8 1 23 778 800 778 800 0.93

7 8 0.00076 0.089 13.3 10.1 1 23 806 828 806 828 0.98

8 8 0.0012 0.14 12.7 4.3 1 21 834 854 834 855 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0027	0.31	11.5	1.1	2	23	53	75	52	75	0.93
2	8	0.17	19	5.9	0.4	8	23	110	125	102	125	0.80
3	8	3.9e-06	0.00046	20.4	0.6	2	23	132	153	131	153	0.97
4	8	7.4e-07	8.7e-05	22.7	5.9	1	23	162	184	162	184	0.99
5	8	3.1e-05	0.0037	17.6	1.0	1	21	190	210	190	211	0.95
6	8	6.8e-06	0.0008	19.7	0.8	1	23	778	800	778	800	0.93
7	8	0.00076	0.089	13.3	10.1	1	23	806	828	806	828	0.98
8	8	0.0012	0.14	12.7	4.3	1	21	834	854	834	855	0.96

Sequence Information

Coding Sequence: atggtggcgcgcggcgcgagcatgTTCGGGTGCTACGACAGCTATTCGTACCGGCTCTGGAGTCTCGCCAACGTGTGGAACACCTGCCAATTGCCATCCCTCGCGCCGAACGGGCTGACCGTCAAAGAGGAGAGCGGCTCCCCCGACTACTTCATCAAGTGTCCACAATGCCAGAAGGGTTGCCAGACCTTTCAGCAGCTGAAGGAGCACATGGAGGCCGCCCATCCGGAGCTGTGCGGCGCGGAGAACGGCTgcgggccgccggcgtcgccgacgccgagccTCGGCGGGCCGGGCGGGCCGTTCGCCTGCGTCCAGTGCGCGCACGCTTCCTTCCCGACCAAGGATCAATTGGAGAAGCACGAACTTCTGCATTCGCCGAACGCGCAAGTCtcttgcaaaatttgcaacaaaACATTCGCGAACGTCTATCGCCTGCAGCGACACATGATCAGCCACGACGAGAGCGTCCTGCTGCGAAAGTTCAAGTGCACCGAGTGCGACAAGGCGTTCAAATTTAAGCATCACTTAAAGGAACACATACGAATCCACAGCGGTGAGAAGCCGTTCGAGTGCGGCAACTGCGGCAAGCGATTCTCGCATTCCGGCTCGTATTCTAGTCACATGACATCGAAAAAGTGCTTGGTTATGAATTTAAAGTTGGGCCGCACGCGcggccccgccgccggcggcaacgcgCTGCTGGAGAAGGCGGGCACGCGCGGACCCAAGCGCTCCTCGAATCCCGgcatcaacaacaacatcaCGACCGCTAATCACAACAGTTACTTGCCGATTCTGCCCAAGTAcaccgacgcggcggcggccacggCGGCGCTGTTCCAGAATCCGGCGATGCATCCGTTCTACAtggcggcgccgggcggcCATCTCAACCCGTATTCGATACCCAACATCGGCCAGATTCTGGAGCAGATGCAGTGCGTGCCTCCGAAGCCGTCGCCTTCGGCGGGCGACGAGGAAGGtccgcagcagcagccgcagcgcggcgatgcCGTGGACGCCAAACCCGAGGCGGTGGAGATCAAGAAGGAGCCGGGCGCGCGGAGCGGTGACGAGCTGGAAATGGGTGCGGACGGCGCCGATGGCAAATGCGCGAAGCGTGAGGCGATGAACGGCGCGGCCGCCATCGGCGATGACTTCGAAGCGGTCAAGCGCATTCTGGCGACGGTGAACGCGTCCGTCACGAAGGAGTTCTTCCGCGCCAACATGCAGAAGTTCTCCGATTCCAATTCCACCTCGGACGATGCGCACTCGATGCGCTCGACGCACTCGCCCTCGGAGCACGAGAGTGCCGAGGCGAGCGAGGCGAAGAGCGAGGGGCTCGCTGCCAAATTGGAGGATGTGCTGGCAACGAACGCGTCCGCGAAAGCCGAAAGCGAATCGCTTAACGGCGCCATCAGCAGCAACGAAGAGGAAGGTGAACGCCGGACCGAGCGCAATGTGGAGTACGAAATGGACGGCGAGTCCATTGCGACGACCGACGCGCAGCTCACTGAAGATGGACGCAAAGTCAGAGTCCGTTCGCTCATTTCCGACGAACAGCTTAAAGTCCTCAAGGACAACTACGCGCTGAATCCTCGCCCGAAGCGCGAGGAGTTGTCGAAAATCGCCGAGCAGATTGGATTTCCCGTGCGCGTGGTCCAAGTGTGGTTTCAGAATACTCGCGCGCGAGACCGGCGGGAAGGGCGGCTCATTAGCGTCCCATACAGCGCGCCGACTCTACTGCCTCCAGCCACGATGGGTTACCTCAAAAGCTACCAGCGAATGGACGACCAACCGTTAGATTTAAGTTTCAAAAAGGAGGCCTCGGGAGAATCGTCGCCGGCCAATTCTCCGCCGAGACCGGCGTCTAGTCACCATTCCGGCGACTCCGGCGAGGAGCTCGCCGTCAACCTGAGTCGCAAGTCGTCGAGAAGTCCCACCCCATTCCAGCATGCGCCATACCACCAGGGATCCAACTCGTCGCTGGATGCCTCACACCGATCGCCATCGCCAATCGATTTAAACAGCAGCCGTTTGGCGCAGATCCTTGCGCAGCCGCACAAGTTGGGCTTGGCGATGGTGCCCATGGAGAGATTGATGCAGTATGGGCCGGCGGACCTGCCCAGCTTGCAGCAGATGATCAGCAGCCGGATGTCGAATATTAGCCCCAATTCCGACAAGCGCTCGTCCTGCTGGGGCGAAAACGGCGACTTGAACGTGGACGACGACGATTCCAACAGCAAGCGCGCCAAGCTGTCTTCGCACCACATGATGCTGAAGAGCTTGGGCAGTCCCAGCGCGCAGGATGGCGAGACGGAGGGGCAGTTCGCCTGCGATCAGTGTGATAAATCGTTTGCGAAACAAAGCTCACTGGCCCGCCACAAATATGAGCACTCAGGCCAACGTCCACACAAGTGCAACGAATGCGCAAAGGCGTTCAAACACAAGCATCACCTCACGGAACACAAGCGTCTTCACAGCGGGGAGAAACCGTTTCAGTGCTCGAAATGCTTGAAGCGCTTTTCGCACTCGGGTTCCTATAGCCAGCACATGAACCATCGCTACTCCTACTGCAAACCCTACAGAGAATAA
Protein Sequence: MVARGASMFGCYDSYSYRLWSLANVWNTCQLPSLAPNGLTVKEESGSPDYFIKCPQCQKGCQTFQQLKEHMEAAHPELCGAENGCGPPASPTPSLGGPGGPFACVQCAHASFPTKDQLEKHELLHSPNAQVSCKICNKTFANVYRLQRHMISHDESVLLRKFKCTECDKAFKFKHHLKEHIRIHSGEKPFECGNCGKRFSHSGSYSSHMTSKKCLVMNLKLGRTRGPAAGGNALLEKAGTRGPKRSSNPGINNNITTANHNSYLPILPKYTDAAAATAALFQNPAMHPFYMAAPGGHLNPYSIPNIGQILEQMQCVPPKPSPSAGDEEGPQQQPQRGDAVDAKPEAVEIKKEPGARSGDELEMGADGADGKCAKREAMNGAAAIGDDFEAVKRILATVNASVTKEFFRANMQKFSDSNSTSDDAHSMRSTHSPSEHESAEASEAKSEGLAAKLEDVLATNASAKAESESLNGAISSNEEEGERRTERNVEYEMDGESIATTDAQLTEDGRKVRVRSLISDEQLKVLKDNYALNPRPKREELSKIAEQIGFPVRVVQVWFQNTRARDRREGRLISVPYSAPTLLPPATMGYLKSYQRMDDQPLDLSFKKEASGESSPANSPPRPASSHHSGDSGEELAVNLSRKSSRSPTPFQHAPYHQGSNSSLDASHRSPSPIDLNSSRLAQILAQPHKLGLAMVPMERLMQYGPADLPSLQQMISSRMSNISPNSDKRSSCWGENGDLNVDDDDSNSKRAKLSSHHMMLKSLGSPSAQDGETEGQFACDQCDKSFAKQSSLARHKYEHSGQRPHKCNECAKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00629693;
90% Identity: iTF_00629693;
80% Identity: iTF_00022095;