Aorb012258.1
Basic Information
- Insect
- Acrocera orbiculus
- Gene Symbol
- L
- Assembly
- GCA_947359355.1
- Location
- OX375758.1:3743513-3752100[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 3.9e-06 0.0003 20.9 1.7 1 23 146 168 146 168 0.98 2 19 0.31 24 5.5 5.7 1 23 174 196 174 196 0.98 3 19 1.7e-07 1.3e-05 25.2 3.1 1 23 202 224 202 224 0.99 4 19 1.4e-05 0.0011 19.2 0.2 1 23 230 252 230 252 0.98 5 19 1.9 1.5e+02 3.0 1.9 2 23 306 329 305 329 0.88 6 19 0.0029 0.23 11.9 0.3 2 23 350 372 349 372 0.96 7 19 0.021 1.6 9.2 0.7 1 23 457 479 457 479 0.96 8 19 0.095 7.5 7.1 1.7 2 23 488 509 487 509 0.95 9 19 0.00023 0.018 15.4 2.7 1 23 517 541 517 541 0.94 10 19 0.22 18 5.9 0.1 1 19 546 564 546 566 0.92 11 19 0.38 30 5.2 2.2 1 23 576 598 576 599 0.95 12 19 0.0037 0.29 11.6 2.4 1 23 631 653 631 654 0.96 13 19 1.1 86 3.8 0.1 2 23 789 812 788 812 0.87 14 19 0.0019 0.15 12.5 5.4 2 23 821 843 820 843 0.97 15 19 0.085 6.7 7.3 0.1 1 23 849 871 849 871 0.92 16 19 3.5 2.8e+02 2.2 0.7 2 23 879 900 879 900 0.94 17 19 0.19 15 6.2 0.2 2 23 985 1006 984 1006 0.94 18 19 0.058 4.6 7.8 0.1 1 23 1016 1038 1016 1038 0.96 19 19 0.015 1.2 9.7 3.5 1 23 1045 1067 1045 1067 0.97
Sequence Information
- Coding Sequence
- ATGGCAATGAAAATGTTGTATCGTGGTCCTAGTTTGCGTCTTGAAACTTTAATTGAAAAAATTCAACAAAGCAAAGAGGTGAACAGTGATTTCTATTCTACTCATACCTCATCAGAATATTCACCTTCAATGTCAGAGGGTGCAGCTACACCAAACTCATTACTACACCATAATCGTCCCTTTGGCCACGATGAGGGTGACAGTAATCGTCTTAGTGTTAATAACCATAACGCGAAAACTTCAGCCGATAATGGTTCTTTGGATGAAAATGAAGATGACGATGTGGAAACGAACTATGAGAGAATTGAATCACATGAAGCAAATGAAAATATTAACAATGGCATATTACCATCAAAAACTCGAAAAATTGAAAGAAACCAAGTGAAAAATGAAAGCTCAAAAGGTGATGGAATCAAAACAACATTAGATGGATCCTATCAATGCCAATTCTGTGACAAATCATTTCCACGTCTTGGTTATTTAAAAAAACATGAACAGAGCCATGCAGAGCATCTTCCGTTCAAATGTGAATATTGTGCACGTCTTTTCAAGCATAAGCGATCACGTGATCGACATACAAAGCTTCATACAGGTGATCGACGGTACCGATGTCCGCATTGTGAGGCTGCTTTTTCGAGAAGTGATCATCTTAAAATTCATATGAAAACACATGATAATCAAAAACCTTTTCAATGTACAGTCTGTAATAGAGGATATAATACGGCTGCTGCATTAACATCACACATGCAAAATCATAAAAAACAAGCAGCATTGTTAGGTTCAAGTCAATCATTGAATTATAGCCCAAGATCAGTTCGTTCAGGATCAAGCAATGGAAGTATACACAAAAGAAAATATGTTAAGAATGAATTGGCACAAGTTGAATTTGGAAAACAATTTCGTGGATCATATATTTCTTGCATGTATTGTACAAAATCAGATTTTTCATCATTTGAACAGCTTAATATGCATATTTGTTCTATGCATGAAGATATCGTAGGCAAAGAAGGAAACCAGTTACAATTTAATAACAAAAACTTTCATTTGAATTGTGAATACTGTACTATGAAATTTCCGAGTGTTCCTGCTATGTTTCAACATATGCGAACAACACACATTGATCGTTTAAGCAGTCCAAACTCATATTTTGTACATTTCAATAGACTTGCTGCTTCAGGCACCTTCAGTCCAAGATTAAATCATTATGATGAATTGAAAGTTAAAATAGAAGGTTTAAGTCCACCTTTAATAAGATCTAGTGTAATAGAGAAAAACGATGAACAAATAAATCCTACCGATCTAAGTCAAAATCGGAAACGAACGCCTAGTCCTGAAAAAGAACTCGATTCATGTAAAACCCCAAGTGCTTTCCTTTGTAATCAATGTAATGCTAGTCTTCCAGATTTTGAAATGTTTCGTACTCACCTTAAGACACATATAACAGAAGAAATGGTTAACTTGACATGCTTTCATTGTAGCTTAAATTTACGTGATCAAAATGAATACGAGCGTCATTTGGTTTCACATTTTCTAATTACGTCTTCAGAATACAGTTGTAGTGATAATTGCAAGAAAACATTTACAAAACACGAGGACTTACAAAAACATCTAATTGAAAATCATTTACAAACTATGTACAAATGTTTGCTTTGTAGCGAAATGTTTGATACAAAAATTGCAATTCAAGTTCATTTTAATTGTGTTCATTCCACTGAAAGCAAAGGATATCGATGTTCAGCCTGTATGGCTACATATCGCAATGAAAATGATTTTTTCGATCACATCAAATCACATCATTCGAATTCCAGTTCAATTCAATGCATGTTCTGTCGTGTGGTCTGTTCTTCCGAACTAGAAATGCATTTTCATTTAGCCGCTCATGCACGACAATTTAGATGTCCTTCCTGTCCTGAAACGTTTCATGTCGAATTTTTACTTGATCGACATATGCAGTTACATCATGCACAAAAATGCTCCAATACTAAAACGAATTCAATAACTGCAGAGACTTATTCACTTCCGATCCAATATAACAAGCAAGAATTAGTTCCTAACAATAACAATAGTATACTAGATTATAACACTTTAGTTACGAACAAATCATTATTTATTCAGACTGGAAGTAAAACGATTCATTCCAATCAGCATCTTTCAGCAAAGCCGCAAGCACTGATGTATGGCCTTGGCCAATGTTATTTTGATCCCAGCAAAACTTTAGCAGATATGTATAATTATCATCAAAATAACAAAATTAGTCCAAGCTTCTTTAGGATACAAAATAATTTTAATGGAATAAAAAATATGAAGACAAAAGAATCCAAGCCAGTAGCAACATCTGAAAAATTTGGAAATTCAACTAGCATTTATTGTGATATATGCGAACGAAATGATTTTCGTTCTGAATCGGAAGTTAATGCTCATCGAAAAATTGCTCACAACTTGAAAACATGGGTAAGTCTAAAGTGTGCTTATTGTAGTGGTAAATTTAAAACACGTAATGAACTTGAGCACCACATGAAAACTTGCCACAGTTCAAATGGAAAACACAAATGCCTTATTTGTGATGAAATTTTTCCTTCACCAGCAATTTTAGCAGAACATAAATTGCAACATTCAAAAATTGGAAAATCTGGAAAATGTTCACATTGTTCAGTACCTATAAGTGATGTGTTAGAATTTAAAACTCATCTTTCCGAGCATAATAGTGAAGGACAAATTCCTGTTCAATGCATTTGCTGTCGACAAACTCTATGTTCAGATTTTGAAGTTAGTCTTCACGCTAAATTCCACACACAATCTTATTCATTCAAAGAAAATGTTTGTGCTTTGTGTCTAAGAGCTCTTCCTGATTCTTCGGATACACGATTATGCGAAAACTGTTGTAAAAAACATGATATAACATCAAAAATGCATCATATACGATTAGAAAGTTCTAAAAGTATTGAAGAAAACAAATGTAACCTTTGCAAAACTATACTACCAAATGCTCAAAAATTACAAGAGCATCTAGTTGAGCATACTTTTATTGGATATGAAGAACGTGGGTATGCATGTTATATTTGTTCCGCAGTATTTACTATCCCTACAGGACTTTTGGGCCATATGCATGAACATGGCTTAGATTCTCGGCCATATGATTGCAATTTTTGTTCAGAGAAATTCTTTTTTAGAGCTGAACTAGAACATCATATTTTTAAACATGAAAAATGTAAACTGTTAAACGGATCTTATGAAAAGGATGCTCAAAAGAATGCTATACTGAATAGAAATGAAATTAATGTGAAAATTGAAAAGAAAAGCAACAACGATGAAGATAATGAAAATGAAGAGGAATATATAGAGGTAGAAAAAATTGCAGAAACCAACATTCAATCTGATGGGGATAATAATTAA
- Protein Sequence
- MAMKMLYRGPSLRLETLIEKIQQSKEVNSDFYSTHTSSEYSPSMSEGAATPNSLLHHNRPFGHDEGDSNRLSVNNHNAKTSADNGSLDENEDDDVETNYERIESHEANENINNGILPSKTRKIERNQVKNESSKGDGIKTTLDGSYQCQFCDKSFPRLGYLKKHEQSHAEHLPFKCEYCARLFKHKRSRDRHTKLHTGDRRYRCPHCEAAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTSHMQNHKKQAALLGSSQSLNYSPRSVRSGSSNGSIHKRKYVKNELAQVEFGKQFRGSYISCMYCTKSDFSSFEQLNMHICSMHEDIVGKEGNQLQFNNKNFHLNCEYCTMKFPSVPAMFQHMRTTHIDRLSSPNSYFVHFNRLAASGTFSPRLNHYDELKVKIEGLSPPLIRSSVIEKNDEQINPTDLSQNRKRTPSPEKELDSCKTPSAFLCNQCNASLPDFEMFRTHLKTHITEEMVNLTCFHCSLNLRDQNEYERHLVSHFLITSSEYSCSDNCKKTFTKHEDLQKHLIENHLQTMYKCLLCSEMFDTKIAIQVHFNCVHSTESKGYRCSACMATYRNENDFFDHIKSHHSNSSSIQCMFCRVVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQLHHAQKCSNTKTNSITAETYSLPIQYNKQELVPNNNNSILDYNTLVTNKSLFIQTGSKTIHSNQHLSAKPQALMYGLGQCYFDPSKTLADMYNYHQNNKISPSFFRIQNNFNGIKNMKTKESKPVATSEKFGNSTSIYCDICERNDFRSESEVNAHRKIAHNLKTWVSLKCAYCSGKFKTRNELEHHMKTCHSSNGKHKCLICDEIFPSPAILAEHKLQHSKIGKSGKCSHCSVPISDVLEFKTHLSEHNSEGQIPVQCICCRQTLCSDFEVSLHAKFHTQSYSFKENVCALCLRALPDSSDTRLCENCCKKHDITSKMHHIRLESSKSIEENKCNLCKTILPNAQKLQEHLVEHTFIGYEERGYACYICSAVFTIPTGLLGHMHEHGLDSRPYDCNFCSEKFFFRAELEHHIFKHEKCKLLNGSYEKDAQKNAILNRNEINVKIEKKSNNDEDNENEEEYIEVEKIAETNIQSDGDNN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -