Aorb002112.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Acrocera orbiculus
Gene Symbol
Kr-h1
Assembly
GCA_947359355.1
Location
OX375757.1:30590236-30594957[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.001 0.081 13.3 2.6 1 23 128 150 128 150 0.99
2 8 1.1e-06 8.6e-05 22.7 1.0 1 23 189 211 189 211 0.99
3 8 1.4e-06 0.00011 22.3 2.5 1 23 217 239 217 239 0.98
4 8 2.7e-07 2.2e-05 24.6 2.8 1 23 245 267 245 267 0.99
5 8 2.8e-07 2.2e-05 24.5 1.7 1 23 273 295 273 295 0.98
6 8 8.1e-05 0.0063 16.8 1.5 1 23 301 325 301 325 0.99
7 8 0.36 28 5.3 3.7 1 23 331 353 331 353 0.94
8 8 7.4e-07 5.8e-05 23.2 0.5 1 23 359 381 359 381 0.98

Sequence Information

Coding Sequence
ATGAGTGCAGAGACATGGAGTAAACAAGATTGGTTCAAAAACGTATTGTCTAAGTCTGGTACTGATATTATGGAAATTAAAAATGAAAATTCAAAAGATATTTGTAAAATGGTTTATTATCCGTCACTTCCATTACTAATGAAGTCTGAACAACAGCAACAAATATGTACCCAAATGAATCCTGAAATGCAATTTTACCAAAATAATTCCATAGTACTTCATCCACAATCTGAAGCAGTTGTTAGTAATAATGCTACAACAAGATTTGCATCACAAAACCAAAGTTATATAAATAATATAAAATTAAAACAAGAACAAGAACATCAATCCCAAAATATAGGATTCGATAAAAATAATTCCGTTAATTATCCTAAGATATCATTTAAATGCGAACAATGTAATACGATATTTGGTAGTAAAAGCGCACATACAATTCATATGAAAACACACTCAAATCAAGACAATAAATATCAAAATACTTCACCTTCGACATCGAATAATGTCCAAGTAACACCAACACAAACAACAGCCCCAATAGCAAATATTGCTACACCTTCGGATCCGTATTCCTGTAATGTTTGTAAGAAAACATTTTCTGTGCCTGCAAGACTGattcgtcattatcgaacgcataccggtgaaaggccttttgaatgtgaattttgtcacaaaatgtttagtgttaaggaaaatcttcaagttcatcgtcgaattcatactaaagaacggccctataaatgtgatgtatgtggccgagcattcgaacatagtggaaaacttcatcgtcatatgcgaattcatactggcgaaaggccacataagtgttctgtttgcagcaaaacatttattcaatctggacaattagttattcatatgcgtacacatactggtgaaaaaccttataaatgccctgtcgaaggctgtggaaaaggttttacatgttctaaacaattaaaagtacattcacgtacacatactggagaaaaaccttatcattgtgatatatgctttcgagattttggttataatcatgtattgaaattacaccGTGTACAACATTATGGATCGAAATGTTATAAATGTACAATATGCGATGAAACATTTAAAAGCAAAAAAGAAATGGAAGCTCATATTAAAGGTCATTCAAATGATATACCAGATGATGAAGATGAAACTATACAACAATCACAAAATATTGTTAAACAAGAAAATATAATTTATAATCGTGAATCATTACCAGAGTCTGAAAAAAGTCGTGATAGTATAGGTACATCGAATGGTAGCGGAAGTATATTATTAGAGACTCCAAGAGAATCTAGTTCAGAAGCTAATTCAGAGAATGGTGAAGAATTAATATATAATAATATGTATGAGAGACTTGAAAGATCTGGTATAACATTATCAATACGTCAAAGTCATTCAAGAATTAATCCAGCATTATTAGCAGCAGCATCAATTGCTAGTCAAAAAGTTGAAGAAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCACAATCATCATCATCAATTGGAATTAATTCTGTTGATCTTACATGTGAAGAAAATGGAATTAATGATTATCATCAAACAAATAAAGAGACCAGAAATAGTACTTCACCGACTCAATATAATTATGATGAACAGATTGCTGTAATGAGACAACATGGATATTTTGGTCCAGCTCCTGTAGCTGAGTATAGGCCATCTCTTCGTGCTGCTAATGATATTGTTCGAAGAGTTGAAGCTGCTATTGCTGGAGCTGAACCTTTATTAACACCGCCAAGATTGTCTTCAACCGAATCACCAGAACGTTCTTCATCACCAGAAAGTGATGTAATGATGATGGCCGATCGGGATGTTATGACTTTACCACTTCGTAAACGTAAATTATATCTAAAAGAGAATCAACAAGATGATATTTCGCCAAAAGTTGTACGTCTAAATGTTATACAATTCGCTAGAGCATCATAA
Protein Sequence
MSAETWSKQDWFKNVLSKSGTDIMEIKNENSKDICKMVYYPSLPLLMKSEQQQQICTQMNPEMQFYQNNSIVLHPQSEAVVSNNATTRFASQNQSYINNIKLKQEQEHQSQNIGFDKNNSVNYPKISFKCEQCNTIFGSKSAHTIHMKTHSNQDNKYQNTSPSTSNNVQVTPTQTTAPIANIATPSDPYSCNVCKKTFSVPARLIRHYRTHTGERPFECEFCHKMFSVKENLQVHRRIHTKERPYKCDVCGRAFEHSGKLHRHMRIHTGERPHKCSVCSKTFIQSGQLVIHMRTHTGEKPYKCPVEGCGKGFTCSKQLKVHSRTHTGEKPYHCDICFRDFGYNHVLKLHRVQHYGSKCYKCTICDETFKSKKEMEAHIKGHSNDIPDDEDETIQQSQNIVKQENIIYNRESLPESEKSRDSIGTSNGSGSILLETPRESSSEANSENGEELIYNNMYERLERSGITLSIRQSHSRINPALLAAASIASQKVEEAAAAAAAAAAQSSSSIGINSVDLTCEENGINDYHQTNKETRNSTSPTQYNYDEQIAVMRQHGYFGPAPVAEYRPSLRAANDIVRRVEAAIAGAEPLLTPPRLSSTESPERSSSPESDVMMMADRDVMTLPLRKRKLYLKENQQDDISPKVVRLNVIQFARAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
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80% Identity
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