Basic Information

Insect: Acraspis erinacei
Gene Symbol: mecom-b
Assembly: GCA_035041075.1
Location: JAWWLR010000167.1:13271314-13320364[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.018 7.2 9.7 0.4 2 23 177 199 176 199 0.94

2 8 8.3e-05 0.033 17.0 0.9 2 23 236 262 235 263 0.87

3 8 4.6e-06 0.0018 21.0 2.6 1 23 269 291 269 291 0.95

4 8 3.1e-05 0.012 18.3 5.1 1 23 297 319 297 319 0.99

5 8 0.00014 0.054 16.4 1.5 2 21 327 346 326 347 0.95

6 8 6.7e-09 2.6e-06 29.9 1.2 1 23 664 686 664 686 0.99

7 8 3.5e-07 0.00014 24.5 1.7 1 23 692 715 692 715 0.97

8 8 2.9e-06 0.0011 21.6 3.4 1 23 721 743 721 743 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.018	7.2	9.7	0.4	2	23	177	199	176	199	0.94
2	8	8.3e-05	0.033	17.0	0.9	2	23	236	262	235	263	0.87
3	8	4.6e-06	0.0018	21.0	2.6	1	23	269	291	269	291	0.95
4	8	3.1e-05	0.012	18.3	5.1	1	23	297	319	297	319	0.99
5	8	0.00014	0.054	16.4	1.5	2	21	327	346	326	347	0.95
6	8	6.7e-09	2.6e-06	29.9	1.2	1	23	664	686	664	686	0.99
7	8	3.5e-07	0.00014	24.5	1.7	1	23	692	715	692	715	0.97
8	8	2.9e-06	0.0011	21.6	3.4	1	23	721	743	721	743	0.99

Sequence Information

Coding Sequence: ATGCGGATCTTGAATCCTGAAGATTTGAACTTGAAAGATTTGAACTTTGAAGAATGTGCTGGAGAGGCTCTTTTGGCTCAGCGAAATCAGACTCGGCTGAGCTCGGCGGCGTTCGGGTGGCGTCGGCTCTCAGTTCGTCTCACCAAGGCAGTGTGTGCGTCAGGAATTTGTGAATGCTCCACGCTTGGCGAAAGATTTCCAAGACTTCTAAGAGTTCGTGTTCCGGGAAGTGGAGCAAGGGGATGGTTTGATGCCTCCCACGAATCAAGTAATTGGCTCAAGTACGTCCGAAGCACAGCAAGTCCTCATACAGTCAACATGCGACATGTTCTCATCGGAGGAGAGgTCGTCTACGAGACAGTGCGAGAAGTAGCAGCCGGCGAAGAGTTATTGTTAGGACTTCGTGAACCTCTTCAACTCCCGGACTTGTTGGGGGAAAACACAACCGAGGACAGAAGCGATCGAGAGACCGCTTCTCAGCATAGTGAAACAATAGATGAAGACCGAGAAGAAGAAGAGGGAGATATAAAATGTACAGTCTGCGACAAACCGTTCCAGGATATCGATGTCTTAGACAATCACCTTGTAACCTGTCACCGATATCCTGCAGAGCAGCATCGCTGTGAGAGTTGTCCAAGTGGCTACGCCTGGCGACCTCTTCTCGTTCGTCATCGCGCCATCGTCCACGGCGACCTTAGAAAATACCTCTGTGAAAATTGCCCAAAGGTTGCAACTTCGCAGGTTTTCACCGATCCATCAAATCTTCAGCGGCACATCAGGTCCCACCACGTCGGAGCCAGAAGCCACGCTTGCACCGAATGTGGAAAAACCTTCGCGACAAGTTCAGGACTCAAACAACACACCCACATCCACAGCAGCGTCAAACCTTTCCAGTGCGAGGTTTGCCTAAAGTCGTACACCCAGTTCTCGAATCTATGTCGCCACAAACGGATGCACGCGGTTTGCCGTACTCCAAGCAAATGTGTTAAGTGTGGTCAATCCTTCAGCACTTCAACATCCCTCTCGAAACACAAGAGATTTTGCGATTCAACGACACCGGCCGGACCACCAGGAACGATGCCTCAACTACCGACTCTCATGAGCCACTATCATGGAATGTTCCCGAGTGCACCCAATTTCCTTAATGCCCCTCTTCTCTTCCACCAAAAAGTCGAGGAAGAGAAGCGAAGTGAGAGTCCCAAAAGGGAACGATTTACCCCACCTAGGGTTGTTCAACAGAGCAAGGTATCTCCATACACTGCTGAAGAAGCTACTTCCACTTTTAGACCATCCCCAGCGAGACCTCCTGTGCACACTCCTGAACCCGAGGAGAGACAGGAGAGACTAGATGTCTCCAAAAACGAGAAGAAGGAACAGAGAGAGTCTGAGAAGCCTGAAGAGAGTGATCAACCTTTAGATCTTAGGGTACAGACCAGGAAACGGGAGAGAACTACTTCTGACTCTATAGTCTCTACAAATAAGATGGAACTTTCCCCTATGTCTGTTGAAGAATCACCCCCAGAGAAGACGAGAAAAAGGACCAACTCTGACTCCAGAGATTCCACACCTAAAATTAGAATTTCCCCTCTTCCAATTCCTGTTGAAGAACCACCGCATGTTGAAGAGAAAGAAATCACTCCTCTCCGAGCGAGTCTTTCGGAGCAACATCCGCCACATATGGCTTATCCTAGACCAATTCATCCAATGTTTCTAGAAGCGATGTACCGACAACCAGGAAGTTTCGCGGGGTTTTCAGGAGCTCCCCCTCCAACCGGTCCCGGAGAATCTCGACTCCTGCCTCCACTTCCTCCTTTTGGTCCTCCCCGTGGGCTTCCTTTTTTAGGCACACTGATGAACGGTTTCAATAGTAGACCAGGAACGTATGATCTGCTAGCAAGACCCTCTATGGCAGGTTATCCGAGTGTCAAACCTTACCAAGACGCTGTAATGCCTCATCATCATCATAACCATGGGAAGATGAAGGACAGGTATTCCTGTAAATTCTGTGGAAAAGTGTTCCCGAGATCTGCCAATTTGACGCGACATTTAAGAACACACACTGGGGAACAACCCTACAAATGCAAATACTGTGAAAGATCCTTCAGCATCTCTAGCAATCTCCAAAGACATGTCAGAAACATTCACGATAAGCAGAGACCTTTTAAGTGTCCTCTCTGTGACCGTTGTTTTGGACAACAGACGAATTTGGATCGTCATTTGAAGAAGCATGAAGCTGATGATGGAAGTGGCGTTGTTGTAGCTGACTCTCCAGGAAGCAGCAACGAGAACGAGAGGGAGGATACCTATTTTGACGAGATTAGATCTTTTATGGGGAAGGTTACTTACGGAGGGGAAGGATACGGTCTTCCTCACCATCCTTATTTGCCGGGAAGACTGCATGAAATGCACGATCCTAAGGGTGATTTTGATGACGATGAGGACAGCGAGGGCGCAGTTTCGCCAATTGAAGAAGGCGACGCTCTGTCTCCAATTCCCAAGGAATCCGCCTCGCCCCAGTTTGATCTTAAGTTAAGAGACAAGCAAAAGCTGCTCAACAACAACACGGCAGAGCCAGTGATCGAGGTTTCCACGTAG
Protein Sequence: MRILNPEDLNLKDLNFEECAGEALLAQRNQTRLSSAAFGWRRLSVRLTKAVCASGICECSTLGERFPRLLRVRVPGSGARGWFDASHESSNWLKYVRSTASPHTVNMRHVLIGGEVVYETVREVAAGEELLLGLREPLQLPDLLGENTTEDRSDRETASQHSETIDEDREEEEGDIKCTVCDKPFQDIDVLDNHLVTCHRYPAEQHRCESCPSGYAWRPLLVRHRAIVHGDLRKYLCENCPKVATSQVFTDPSNLQRHIRSHHVGARSHACTECGKTFATSSGLKQHTHIHSSVKPFQCEVCLKSYTQFSNLCRHKRMHAVCRTPSKCVKCGQSFSTSTSLSKHKRFCDSTTPAGPPGTMPQLPTLMSHYHGMFPSAPNFLNAPLLFHQKVEEEKRSESPKRERFTPPRVVQQSKVSPYTAEEATSTFRPSPARPPVHTPEPEERQERLDVSKNEKKEQRESEKPEESDQPLDLRVQTRKRERTTSDSIVSTNKMELSPMSVEESPPEKTRKRTNSDSRDSTPKIRISPLPIPVEEPPHVEEKEITPLRASLSEQHPPHMAYPRPIHPMFLEAMYRQPGSFAGFSGAPPPTGPGESRLLPPLPPFGPPRGLPFLGTLMNGFNSRPGTYDLLARPSMAGYPSVKPYQDAVMPHHHHNHGKMKDRYSCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHDKQRPFKCPLCDRCFGQQTNLDRHLKKHEADDGSGVVVADSPGSSNENEREDTYFDEIRSFMGKVTYGGEGYGLPHHPYLPGRLHEMHDPKGDFDDDEDSEGAVSPIEEGDALSPIPKESASPQFDLKLRDKQKLLNNNTAEPVIEVST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00980374;
90% Identity: iTF_00064684;
80% Identity: -