Basic Information

Gene Symbol
HIVEP1
Assembly
GCA_963966035.1
Location
OZ014440.1:8141701-8150168[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 9.3e-05 0.0094 17.5 0.6 1 23 141 163 141 163 0.98
2 8 0.00068 0.068 14.8 1.2 1 23 169 193 169 193 0.89
3 8 0.0027 0.27 12.9 0.0 1 20 422 441 422 443 0.94
4 8 2.8e-06 0.00028 22.3 2.0 1 23 1191 1213 1191 1213 0.99
5 8 6.2e-05 0.0062 18.0 3.2 1 23 1219 1243 1219 1243 0.92
6 8 9.5e-06 0.00095 20.6 0.8 2 23 1520 1541 1520 1541 0.97
7 8 0.0033 0.33 12.6 1.4 1 23 1547 1571 1547 1571 0.91
8 8 0.0014 0.14 13.8 2.6 1 23 1592 1616 1592 1616 0.93

Sequence Information

Coding Sequence
ATGCCTCTCACTCAGGAAAAACGTTTGGATAATAACTTTACCAACAACAATGATCACAGTTACCTgcataaaaagtttaaaaaaatggcatcgTCTATTACAGTGTTCCCAGTTAACACAGTTAAAGCCGGGGAAACAAAACATAAAGAGATTAATGCAGAAGACACGACACGTTATATTACAAACGGGAGCATTCAAGCCGCTCATCCAGAAATCGAAAAGATAAAAGGAATGCAAAATAATCAGCACTTGGGTGTTATACATGTACAAACTAATGttagtgatgagaataatagATTTAGTGATGTAAATACTATTGATCAAGTAGCTGGTAAGACCAGTTTCAATGATGAATTTTCAAACAAGACTGAGAaccttgaaaatgattttagagATGTTCAGAGTGGAACAGGTGGGCGGTATGTGTGCCCATACTGTAAATTATCTTGTGCCAAGCCTTCAGTTCTTCAAAAACATATCAGAGCTCATACTAACGAGAGACCTTACCCCTGTGTACCTTGTGGCTTTGCCTTCAAAACGAAATCAAATCTTTATAAACATAGAAGATCCCGAACACACGCTTTAAGATTACAAGGAGGTGACGTTTCTGCTACAATTAATGAAGAAGATATCTCAGGTGGGTCAGAAAGCGATACATCTTTACCCCCGACTGCGATGTCAGATTCTGGGACTGATTCGACTGTTATTCGCCTAGAAAATGCAAGGCCTTATGATTTTTCATCACCTGAGTTGACAAACGATCGCATTACTCCGCCAACGGGTGCAGATGCGCACTTCAGTGAAAACACTAAATCAAAAACGATTTACAAACCAAAGTTTCGTGCAGCGTTTTATGAAGAAACAGATgacaaaaataagttaaaaaggACAATTTCCTCGAATGCTGATTTTCTTACAGAACATATCTccaaaattatatcaaataatGAAGCAATCGTTGATGTCATCGAAACGCCATTGCAGAAAAAATATGGTAAAATCAAGCAAATAGCAGAAAGCAAACAATTTCTGAATGAACTTGAAATTAAAACTGAACCGTCGCCACTTAACTTGACAAAAAACTGCAATGATACCGATAGTGTTTTTCGGAAACGATCTCATTCAGAAAGCTTTTCGCAAACAGATCATCAGAAACATCCATTGAATCCAGAAGGGTCGATTATAAAAGATCTACTCCTAAAAACGAAGTATAATGGTTTGACATCTGTTACGGGGGAGTTTATTGACGGGTCAGCACTTCTTTATATTTGCCCACTGTGTCAGATTGTCTATAAAAGCGCTGAGAACTTGGAAATACACAGATTATATTACTGTAAAGGTAATTTCTCTAATAATAACACGATGAATACTGTGCAGAAAGAAGTTAAAGTTGGCAGACCCGAAAACGTCTACGTAAGAAGCAATTCAGTGAACGTTCGACTTCCTGAAACATCTTCAATGGCAAAACCGCAAGTTTTTAACAAATCACCTCCGTTAAAAATTAAACCGGATAATTTGATCATCGTCAAACCAGAGTCAAATGACGTTGTTGCCCCATTGCCATCGCCCGGACCTCTGCTCGGAAATACGAGACTTGTTGATACAAGAGTATCTAACGATTTTAACAGAAGAACTGAAACTTTGATGAAACATAAATCATTATCGTCTAGCCCCAAAAGGAAAATTGACAGCAATTCTGATCCATACAGCCCTAGATTGATAGAAAATATTTCTCCGAGATCATCTGATGTGTATAGTCAACCTAAAATAAGATGTATCGAAGGTAATGTTACGACATTAAGGTCAATGGATGAAATTTCCCAACTTGGACGGCATAATTCGGCATCGTTGCAGATGTTTGGAGGTGAAGTCAAAATAGTCCATCATTCTGGCAGCACTACTACCCTACGTATTGAACCAAGTAAAAATCAACTCTCACCAATATCAATTCAGCCTAATTTATCGCCGTCAAAATTGGGCAATGATATGGAAGCCAGCAGTGTTGTAGTGAGATCTGGTCTTCATTCAGGAGGGACTATTGTACACAATCCTCCAACACCAAAAGAAATAATGGGAACTCCGAAACCTCAAACCCCTAGAATAACAGTATCAACAGTGACCGGGATTTCTAATAATTTACCAAACATTCATGATATAACCCATTTCCAATTTCCACCTCTGAGTGCTATAACCGCATTTAACCCTCTGACCTTGCCTCCGCTTAGCCCATCATCGTCTCCTAACGGCGCTACAACAATCCTCCATGGGGGAAAATTAATTCCTCATGTTCCAGGAATACCAGGACCTAATACGCCTGGTACAAATGTTGCTACATTATCTAAAAATACAGATTATTTTAGCTCGGTGGAATCCGACAAAATTCAAGGAAATTATACCGTCAATGGCCAATTAGCAAAGGGAATTGTTACCCCCaaatacgaaataaataaaaacgacacCATGCGAAGTATCAGAAGTCCTAACTGCAGGACAATAAATTTAGATTCTGACAAACATTTTCAAAAACCAATTAAACCTGATATGCCGCACTATGTTGCTGCGGTGCCCATAATTAATGTGAAGAACGTAGATGAACCTTACATCACACAAAAAACATTGACTAACAGTAAAACAATTACGATAACACAAGATGTGACAATAAAGAGAACTTGTGAAGGTATACCCAGGATGACCGTATTTAAAGAGAATGCAAATCTTTCATTAGCGAAGGCGAGGTATTTCGATAAACTTAATGTACCCAAAAGCGTCGATTCAAAAGCTCaaatcgaaatcaaaaattataattttgaaaatcttATTACTAAAGTAGAAATATTCAATAATCAAATTCCAAGTTCAGCTGAAGTACAAAAGAACACCAATGCCCAAGAGATGGTTGCTGCTGCGATTTATAATGAGAGATCAGAGACAGCGTATTTTCAAAAAAGCATATCCGTCAAATCCATTGGAGAAGATCGGAAACCAAAGTTTCTAAGACCTTCAACACTGCCATTAAAACCTGGTACATTTACACCTAAGAGGCATCACGGTATAACACCTAATGCAAATACAATGCCATTAGTTTCCCCTGAAACTCCGCGTCCTGCCAAGGCTTATGGACAACTGTATTTGAACGGGAACGCCTATACATATTTGGGACTGAAGTGTTCAACTAAAGTGTTTTACTGCACTATAAATCGACCTCAACCAACTTATGTTCCTAATCAACATTTCCTGTCGATGTACAGCAATTGGCAgTTATTATCAGAGCTAACGCCAGACCCGCTGGGGCTCTCTGCTTCGTCTGCCATGTCTCTTTATGACTCACGTCATCGACCGCAAAACGTGGCCAGTTCTGCGATTAAACAGGATCTTATACTGACGCATTCATCGCAATGGAATCAAATTACGAATGATGGCAAGCAGTCAATATTAGGTACGGACCCCAAGATAGCAGAGGATAATAAACAACACATAACAGAGAATGCCATTACTCCTAAAAAAGAGTTGGCAGGAGGATTTGAAAGCAACGAAGAATATACATACGTGCGTGGTCGCGGCAGAGGGCGGTACGTTTGCTCAGAATGTGGTATTCGTTGCAAGAAACCGTCAATGTTAAAGAAACATATAAGAACTCATACTGATGTGCGCCCTTACACTTGTGTGCATTGTGCCTTCAGttttaaaacaaaaggaAACCTGACAAAACATATGAAAAGTAAAGCGCACTTTAAAAAGTGTTGCGAATTGGGGATCAATCCGAATGAAGGCAACGATAGCGAGGGCTGCGAGTTGACGCTGGGCTCGGGAGAGACGGACGATGATTCCGACTCCGACGGAGATGAAGGCAACGAAGGCGAAACGGAATCCAGTGACACAGAAGCTTGCAAATCCCGTCTACCAGAACACGAAGCAGCTCACTGTTTACTGTCTCTGGGAGGCAGCAGACCAGCAACTTCTGCGACGCCGGGTCTGATAACCAGCGCTAGGCCGTCCACATATCCTTATACGCCAACTGAAGGAGAAAATGTCATGCACATTGAATATGCTAACCGCGTTATTATGCCTATTGCATCATCTCAACCTAACGTCAGTATTTCAAAAACACCGACATTAATCGAGAATGATCGTCTCACTTCACCAATGAACACTTCGAAGGATGATAACTTAGCGTTAAGTACTGATGTGCCGGTATCAAATAATTTAGTTATTGAGGCGAAAAGAAATCGTACCGCTAGTACTTCCAATGCTGAAAACGCAAAACACGTCGTTTCAGAGTACCTTAAGCATGCCCgtataaatcaaatcaaaacataTGATGATAACACGCAAAACCTACCAGATAATTCCTGTGACAACAGTCCCATGAATATGGAAGAAAGAGACGAGTTAAACCACTGCGATGCAGATACATTAAAAATGTCTATAGACCATGACCCTGTTGCTAGAAAAGTCGTGATAGGTGCAGGTGGCGTAGCCTTTAAAGTGACTAAGGGAAAAGAATTTGAAGGATCCTCGTCTTATACGCCAGGGAGACTTATGGAGGATGGACGTAGAGTATGCGATTTCTGCAACAAATCATTTACCAAACCATCACAACTCAGGTTGCATCTGAACATCCATTACATGGAAAGACCGTTCAGATGCAGTGCATGCGCTGTAAGTTTTAGGACTCGAGGACATCTACAGAAACATGAGCGATCAGGATCTCATCATAATAAAGTGTCGATGACGTCTACATTCGGAGCTGCAACTTCCTTAAATCCTAGACCGTTCCGTTGTTCAGATTGCAACATCGCTTTTAGAATACATGGTCATTTAGCCAAGCACCTGAGGAGTAAAATGCATGTCATGCGTTTAGAATGTTTGTATAAGCTGCCTTTCGGAACGTTTACGGAGATAGAGCGTGCTGGTGTTAGTTTAACGGACATCGACACGACGGACTGCGCGAGCTCGCTGGCTAGCTTGCAGTCGCTGGCGCGCAAGCTGCACGAGAAGGATCCCACCAAGCTGGAGTACCGCGAGCCGAGCGGCGCGGCGACCCCGGCGCCGGCGCCCGGGCCCGTGCCCCACTCCGACGAGGACGACGACGCGGCCCACAATAATTAG
Protein Sequence
MPLTQEKRLDNNFTNNNDHSYLHKKFKKMASSITVFPVNTVKAGETKHKEINAEDTTRYITNGSIQAAHPEIEKIKGMQNNQHLGVIHVQTNVSDENNRFSDVNTIDQVAGKTSFNDEFSNKTENLENDFRDVQSGTGGRYVCPYCKLSCAKPSVLQKHIRAHTNERPYPCVPCGFAFKTKSNLYKHRRSRTHALRLQGGDVSATINEEDISGGSESDTSLPPTAMSDSGTDSTVIRLENARPYDFSSPELTNDRITPPTGADAHFSENTKSKTIYKPKFRAAFYEETDDKNKLKRTISSNADFLTEHISKIISNNEAIVDVIETPLQKKYGKIKQIAESKQFLNELEIKTEPSPLNLTKNCNDTDSVFRKRSHSESFSQTDHQKHPLNPEGSIIKDLLLKTKYNGLTSVTGEFIDGSALLYICPLCQIVYKSAENLEIHRLYYCKGNFSNNNTMNTVQKEVKVGRPENVYVRSNSVNVRLPETSSMAKPQVFNKSPPLKIKPDNLIIVKPESNDVVAPLPSPGPLLGNTRLVDTRVSNDFNRRTETLMKHKSLSSSPKRKIDSNSDPYSPRLIENISPRSSDVYSQPKIRCIEGNVTTLRSMDEISQLGRHNSASLQMFGGEVKIVHHSGSTTTLRIEPSKNQLSPISIQPNLSPSKLGNDMEASSVVVRSGLHSGGTIVHNPPTPKEIMGTPKPQTPRITVSTVTGISNNLPNIHDITHFQFPPLSAITAFNPLTLPPLSPSSSPNGATTILHGGKLIPHVPGIPGPNTPGTNVATLSKNTDYFSSVESDKIQGNYTVNGQLAKGIVTPKYEINKNDTMRSIRSPNCRTINLDSDKHFQKPIKPDMPHYVAAVPIINVKNVDEPYITQKTLTNSKTITITQDVTIKRTCEGIPRMTVFKENANLSLAKARYFDKLNVPKSVDSKAQIEIKNYNFENLITKVEIFNNQIPSSAEVQKNTNAQEMVAAAIYNERSETAYFQKSISVKSIGEDRKPKFLRPSTLPLKPGTFTPKRHHGITPNANTMPLVSPETPRPAKAYGQLYLNGNAYTYLGLKCSTKVFYCTINRPQPTYVPNQHFLSMYSNWQLLSELTPDPLGLSASSAMSLYDSRHRPQNVASSAIKQDLILTHSSQWNQITNDGKQSILGTDPKIAEDNKQHITENAITPKKELAGGFESNEEYTYVRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPYTCVHCAFSFKTKGNLTKHMKSKAHFKKCCELGINPNEGNDSEGCELTLGSGETDDDSDSDGDEGNEGETESSDTEACKSRLPEHEAAHCLLSLGGSRPATSATPGLITSARPSTYPYTPTEGENVMHIEYANRVIMPIASSQPNVSISKTPTLIENDRLTSPMNTSKDDNLALSTDVPVSNNLVIEAKRNRTASTSNAENAKHVVSEYLKHARINQIKTYDDNTQNLPDNSCDNSPMNMEERDELNHCDADTLKMSIDHDPVARKVVIGAGGVAFKVTKGKEFEGSSSYTPGRLMEDGRRVCDFCNKSFTKPSQLRLHLNIHYMERPFRCSACAVSFRTRGHLQKHERSGSHHNKVSMTSTFGAATSLNPRPFRCSDCNIAFRIHGHLAKHLRSKMHVMRLECLYKLPFGTFTEIERAGVSLTDIDTTDCASSLASLQSLARKLHEKDPTKLEYREPSGAATPAPAPGPVPHSDEDDDAAHNN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01464454;
90% Identity
-
80% Identity
-