Basic Information

Insect: Acleris holmiana
Gene Symbol: THAP6
Assembly: GCA_949316455.1
Location: OX438777.1:5936244-5956337[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0066 0.77 11.6 5.3 1 23 362 384 362 384 0.99

2 12 0.51 60 5.6 0.1 3 23 393 414 392 414 0.94

3 12 0.83 98 5.0 2.9 1 23 418 440 418 440 0.94

4 12 0.0022 0.26 13.1 0.1 1 23 445 468 445 468 0.96

5 12 0.13 16 7.5 0.1 1 21 472 492 472 495 0.86

6 12 0.13 16 7.5 0.7 1 22 507 528 507 532 0.92

7 12 0.00096 0.11 14.2 0.1 2 23 551 573 551 573 0.94

8 12 0.23 27 6.7 2.5 2 23 593 615 592 615 0.95

9 12 0.0016 0.19 13.5 0.5 2 23 629 650 629 650 0.96

10 12 0.0089 1 11.2 0.1 2 23 656 677 655 677 0.95

11 12 0.00073 0.085 14.6 0.9 1 23 683 705 683 705 0.94

12 12 6e-06 0.0007 21.2 1.4 1 23 711 734 711 734 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0066	0.77	11.6	5.3	1	23	362	384	362	384	0.99
2	12	0.51	60	5.6	0.1	3	23	393	414	392	414	0.94
3	12	0.83	98	5.0	2.9	1	23	418	440	418	440	0.94
4	12	0.0022	0.26	13.1	0.1	1	23	445	468	445	468	0.96
5	12	0.13	16	7.5	0.1	1	21	472	492	472	495	0.86
6	12	0.13	16	7.5	0.7	1	22	507	528	507	532	0.92
7	12	0.00096	0.11	14.2	0.1	2	23	551	573	551	573	0.94
8	12	0.23	27	6.7	2.5	2	23	593	615	592	615	0.95
9	12	0.0016	0.19	13.5	0.5	2	23	629	650	629	650	0.96
10	12	0.0089	1	11.2	0.1	2	23	656	677	655	677	0.95
11	12	0.00073	0.085	14.6	0.9	1	23	683	705	683	705	0.94
12	12	6e-06	0.0007	21.2	1.4	1	23	711	734	711	734	0.98

Sequence Information

Coding Sequence: ATGGTTGCATACTGTTGTGTGAAAGGTTGTAGTAACAACAGCAGCAACAAGAAAAAAGATCCCAATGATATAACATCGTTTCACGCATTTCCTTCAAATAacgaaatgaaacaaaaatggcTCCTTGCCATCGGCCGGCCGGACTGGGCTCCCCCGAGCTACGCGCGCCTGTGTAGCGCGCACTTCAGCTATGAACAGATAAACCACGATGGACGAAGGATCCGGATCAAAGATGACGCTGTACCGGTTAAGGATTTACCAGTCAACTCTAACTTTGAGGCGTCCCACGTGGAAGTGTGTCGGTTCTGTCTGGCTGCTGATCTGAAGATGTACAGCCTTCAGACAGGAGTGCACCAGGTGTACTTGGAGTCTATCATTGGGTATAATGAGAATTATAAAATTGAAGGTCTTCCACAATTTGTTTGTTACGAATGCGCAGCCCATCTAAAGAGATGCTATAATCTGTTAGAAAAAAGTATGATAGCTCAAGCAACCCTACTTGACATATTTGCCCGTAATGGCAAGATAACTAAAAACCTTATAAACTTACAAAGTAGAAAGGAACTCAATCTGTCTTCATCATTGGCaatttatgaaattaatacaAACATTGAATTTAAAAGCAGTGATAGTTCAGAACTCCTGAACATCACTATTAGTGAAAATGAAGATCAAAGTAGAAATctggaaaaaataaatgataatatacTTATAATAGAGAAAACAAATGAACCAATATCTGAAGATGTCAGTGAAATGCACTTTGAAACAATGGACATTAATTTAAGTGACAGCCAAGATGACACTATTGGCATTACAGATATGAATGATGAACTTGATGATTCTACAGAAAAAATAAGTTCTGATGATGAAGTTAAACCTGTTATTCCGGATACTGTAATAGAAAGAGAAACTAGAGGTAATAAGGCAAGAAACAAACAAATCAAGTCCATTAATAATGCAGGGCTCACTCCAGATGAAGTGAAGATGcaaaagtattttaacattCAATGGTTAACATTAGATCAACAAATAGAAGAATGGAACAGAACAAAAGGAATGAAACAATGCAATGGTGAATCATTTAAATGTCAGATTTGTTCCAAAGTGTTTGCTCACATCAATACTTATCATCTGCACACACGCAGCCACGACCCCATTAGGGGCAAATCTGCATGTGTGGTGTGTAAGTTGCGGTTTAAGAACGAGGTGCTGGCCCGCTCCCACGCCAACCGCGCCCACGCCAAGAAGTTCCATTGCAGGGCGTGCCCGAAGAGTTTCAATAATGTCGCCGTAGCAAAGAAGCACCACAAGTGGCACTGGGGCTACGTGTACCAGTGCGCGGACTGCCCGTTCAGCAGCGCGCACGCGTCGGCGCTGTCGGcgcacgcgcgcgcgcagcacgcCGGCGCGCACGCCTGCGCGCGCTGCGGACACGCCTTCGTCAGCGCGCGCGGCCTGGCGCTGCACGCCGCCGCCGTCCACCTCGACTGGCCTGAGCCGGAAGACAACGAAAAGTACAGCTGTCAGCAATGCAGTCTTAACTTCAAATCCGAAGGCGCGAGGAGAGTTCACCTGCTAACGTCGAAACAGCATAAGAGGAATACTAGTTTATGCGATCCTACTCCTCAAGACCCGAGCCTCAAAAACACGTGCAATAAATGCGGCATCGAGTTCTCGACGCTCAAGGAACTAGTTGAGCACGGTAGAGCGGAGCACAGGAGAGCGAGACAGAAGAAAACCAGCTGGAGTCGCCCAGATGACTGCTATCCGACGCCGTGCGAACATTGCGGCACAACGGTGAATAGCCGGAAGGAGCACTGGTTGCACATCCGGCGGCAGCACCCCGCCGAGCGCGGCTCCTACCGGCCCGTCGTCACCGCCGTCTGCGACACCTGCGGCAAGGGCTTCCAGAACGCGACCAAGCTGCAGCTGCACTCGCTGCGTCACGGCGCGCCGGGCGTGCGGTGCGGGCGCTGCGCGCGCGTGTTCTTCGACAAGTACGCGCTGGCGCGCCACGCCGCCGTGCacgccgccgcgcgcccgcaCGCCTGCCGCGCCTGCCCGCGCGCCTTCAAGCAGCGCGCCAACCTCGACAGGCACTCCAGGGTGCACACAGGCGTGACCCCCTACGAGTGTACAATGTGCGGCAAGAAGTTCAAGTACTCGACGAGCATGAATCTGCACGTGCGCACCGTTCACTACAAGCTGCCGCATCCGCCGCGCAAGAAGAAGAAACCTAAGCAGGCCGATCAAGACAGTTTcgggaaataa
Protein Sequence: MVAYCCVKGCSNNSSNKKKDPNDITSFHAFPSNNEMKQKWLLAIGRPDWAPPSYARLCSAHFSYEQINHDGRRIRIKDDAVPVKDLPVNSNFEASHVEVCRFCLAADLKMYSLQTGVHQVYLESIIGYNENYKIEGLPQFVCYECAAHLKRCYNLLEKSMIAQATLLDIFARNGKITKNLINLQSRKELNLSSSLAIYEINTNIEFKSSDSSELLNITISENEDQSRNLEKINDNILIIEKTNEPISEDVSEMHFETMDINLSDSQDDTIGITDMNDELDDSTEKISSDDEVKPVIPDTVIERETRGNKARNKQIKSINNAGLTPDEVKMQKYFNIQWLTLDQQIEEWNRTKGMKQCNGESFKCQICSKVFAHINTYHLHTRSHDPIRGKSACVVCKLRFKNEVLARSHANRAHAKKFHCRACPKSFNNVAVAKKHHKWHWGYVYQCADCPFSSAHASALSAHARAQHAGAHACARCGHAFVSARGLALHAAAVHLDWPEPEDNEKYSCQQCSLNFKSEGARRVHLLTSKQHKRNTSLCDPTPQDPSLKNTCNKCGIEFSTLKELVEHGRAEHRRARQKKTSWSRPDDCYPTPCEHCGTTVNSRKEHWLHIRRQHPAERGSYRPVVTAVCDTCGKGFQNATKLQLHSLRHGAPGVRCGRCARVFFDKYALARHAAVHAAARPHACRACPRAFKQRANLDRHSRVHTGVTPYECTMCGKKFKYSTSMNLHVRTVHYKLPHPPRKKKKPKQADQDSFGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00009094; iTF_00010133; iTF_00010675; iTF_01464219; iTF_01464505;
90% Identity: iTF_00009094;
80% Identity: iTF_00009094;