Basic Information

Insect: Acleris holmiana
Gene Symbol: ZFY
Assembly: GCA_949316455.1
Location: OX438789.1:678612-690492[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 33 0.00087 0.1 14.4 2.1 2 21 166 185 165 186 0.93

2 33 0.16 19 7.2 0.1 1 23 219 242 219 242 0.94

3 33 0.00013 0.016 16.9 2.1 2 23 248 269 247 269 0.95

4 33 0.0032 0.38 12.5 1.8 2 21 273 292 272 293 0.92

5 33 0.14 16 7.4 0.2 2 23 336 358 335 358 0.94

6 33 1.2 1.4e+02 4.5 0.5 2 23 365 385 364 385 0.76

7 33 0.0065 0.76 11.6 0.4 1 23 391 413 391 413 0.98

8 33 0.015 1.7 10.5 0.8 1 23 419 442 419 442 0.97

9 33 0.006 0.71 11.7 0.2 1 23 451 474 451 474 0.97

10 33 0.044 5.1 9.0 6.6 1 23 484 506 484 506 0.98

11 33 2.1 2.5e+02 3.7 1.3 2 10 645 653 644 665 0.77

12 33 1.2 1.4e+02 4.5 0.6 2 23 696 718 695 718 0.95

13 33 0.006 0.7 11.7 5.2 1 23 723 746 723 746 0.96

14 33 0.9 1.1e+02 4.9 3.8 3 21 751 769 750 770 0.93

15 33 0.00052 0.061 15.1 0.1 1 23 781 804 781 804 0.94

16 33 9.3e-05 0.011 17.4 3.9 1 23 811 833 811 833 0.98

17 33 0.014 1.6 10.6 1.1 1 23 840 862 840 862 0.98

18 33 5.6e-05 0.0066 18.1 0.2 2 21 983 1002 982 1003 0.94

19 33 0.029 3.4 9.6 0.8 3 23 1036 1056 1035 1057 0.95

20 33 0.0024 0.29 12.9 0.1 3 23 1064 1084 1062 1084 0.96

21 33 4.9 5.8e+02 2.5 7.7 1 22 1087 1108 1087 1108 0.94

22 33 0.0033 0.39 12.5 0.2 1 23 1120 1143 1120 1143 0.94

23 33 0.00022 0.025 16.3 1.0 1 23 1149 1171 1149 1171 0.96

24 33 3.5 4.1e+02 3.0 0.3 1 23 1205 1228 1205 1228 0.87

25 33 8.4e-05 0.0099 17.5 0.9 2 21 1355 1374 1354 1375 0.92

26 33 8.8 1e+03 1.8 0.2 1 19 1408 1426 1408 1431 0.83

27 33 0.042 5 9.0 0.8 2 23 1436 1457 1435 1457 0.95

28 33 0.57 67 5.5 1.9 2 21 1461 1480 1461 1481 0.92

29 33 1.5e-05 0.0018 19.9 1.0 1 23 1507 1530 1507 1530 0.95

30 33 0.0022 0.26 13.1 0.4 1 23 1536 1558 1536 1558 0.92

31 33 2 2.3e+02 3.8 0.1 3 23 1566 1586 1564 1586 0.97

32 33 0.1 12 7.8 1.7 1 23 1592 1615 1592 1615 0.96

33 33 0.032 3.7 9.4 1.9 3 23 1623 1644 1621 1644 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	33	0.00087	0.1	14.4	2.1	2	21	166	185	165	186	0.93
2	33	0.16	19	7.2	0.1	1	23	219	242	219	242	0.94
3	33	0.00013	0.016	16.9	2.1	2	23	248	269	247	269	0.95
4	33	0.0032	0.38	12.5	1.8	2	21	273	292	272	293	0.92
5	33	0.14	16	7.4	0.2	2	23	336	358	335	358	0.94
6	33	1.2	1.4e+02	4.5	0.5	2	23	365	385	364	385	0.76
7	33	0.0065	0.76	11.6	0.4	1	23	391	413	391	413	0.98
8	33	0.015	1.7	10.5	0.8	1	23	419	442	419	442	0.97
9	33	0.006	0.71	11.7	0.2	1	23	451	474	451	474	0.97
10	33	0.044	5.1	9.0	6.6	1	23	484	506	484	506	0.98
11	33	2.1	2.5e+02	3.7	1.3	2	10	645	653	644	665	0.77
12	33	1.2	1.4e+02	4.5	0.6	2	23	696	718	695	718	0.95
13	33	0.006	0.7	11.7	5.2	1	23	723	746	723	746	0.96
14	33	0.9	1.1e+02	4.9	3.8	3	21	751	769	750	770	0.93
15	33	0.00052	0.061	15.1	0.1	1	23	781	804	781	804	0.94
16	33	9.3e-05	0.011	17.4	3.9	1	23	811	833	811	833	0.98
17	33	0.014	1.6	10.6	1.1	1	23	840	862	840	862	0.98
18	33	5.6e-05	0.0066	18.1	0.2	2	21	983	1002	982	1003	0.94
19	33	0.029	3.4	9.6	0.8	3	23	1036	1056	1035	1057	0.95
20	33	0.0024	0.29	12.9	0.1	3	23	1064	1084	1062	1084	0.96
21	33	4.9	5.8e+02	2.5	7.7	1	22	1087	1108	1087	1108	0.94
22	33	0.0033	0.39	12.5	0.2	1	23	1120	1143	1120	1143	0.94
23	33	0.00022	0.025	16.3	1.0	1	23	1149	1171	1149	1171	0.96
24	33	3.5	4.1e+02	3.0	0.3	1	23	1205	1228	1205	1228	0.87
25	33	8.4e-05	0.0099	17.5	0.9	2	21	1355	1374	1354	1375	0.92
26	33	8.8	1e+03	1.8	0.2	1	19	1408	1426	1408	1431	0.83
27	33	0.042	5	9.0	0.8	2	23	1436	1457	1435	1457	0.95
28	33	0.57	67	5.5	1.9	2	21	1461	1480	1461	1481	0.92
29	33	1.5e-05	0.0018	19.9	1.0	1	23	1507	1530	1507	1530	0.95
30	33	0.0022	0.26	13.1	0.4	1	23	1536	1558	1536	1558	0.92
31	33	2	2.3e+02	3.8	0.1	3	23	1566	1586	1564	1586	0.97
32	33	0.1	12	7.8	1.7	1	23	1592	1615	1592	1615	0.96
33	33	0.032	3.7	9.4	1.9	3	23	1623	1644	1621	1644	0.95

Sequence Information

Coding Sequence: ATGAACCGGCAAGTGGACATAAAAGCTTTGGTGTCTCACATAGTGCGGGGTGATGGTTTGGATAAATGCCGAATCTGTATGGGAGATACAACTGAAGGCCAAGTTTACCTCGGGGATACAGTAATGATGGATGGAGAAAGACCAGTTACGCTCGCTGAATTACTGGAAATAATCACAGGCATCGAGGTTCATACGGAGGAGGACCTGCCATCCGGACTGTGCACAGTCTGCACAGAGAGAGCCATGGAGGCTGCAAACTTTCGAAACCAATGCCGGCAAGCTGTAAACCAGTGGGAGTCCACTCTACAACTACTAAACAACACACCGATCAAAGACAAGTTCTTGAAAAAGATGTTTATCATAGTAGAGAAGGATCAGATTGTGATGGTTGATAGCTTAAAAGATTTCAATCGTACTCAACTCGCAGCAGAAAGGCGGTCTTCACGGGTACAGAAATTTAAAAGGAGAAGTGCGAGGGAGGGCAAGCATAAATGTCAATGCACAGATTGTGGAAAGAAATTTGCATACGCTCAACATTTGTACTTACACTTGAAGGAATCTACGGACTTTAAGCGGGCTTGTTACATCTGCGCTCAGATTATGACAAGAGATgctttaattttgcatttaaaCAAGGTTCATAAGCTGGAAACCTTTGATTGTAAAAAATGTCCAGCTTTAGTGCGGTCAGAAAAGTTGCTTGCTAAGCATATGGAGGAGGCACACAGCTCTGGAGCTTGCACTTGTGGTGACTGCGGACGTAGTTTCAAGTCTAAACCAGCTTTTCACGCTCATATATCTATTCATACCGTCAAGACTTGCCCTGGCTGTGATAAAGTGTTCCGCAACCAAACTTGCTACTTGTACCATGTCAAGAAATGCTGCAACTTAGACAGCAGTAGAAAAACACATTGGactaaaaacaaagttatgatTGAGGTTAAAAACAAGAACAGTGAGCGGAGAACGAAAGTAGGTCTCCGTGGTGCAGCAGACAAAGAATGCATTTGCGATTACTGCGGGAAGAAACTAGCTGGCAAGAAATTTATAGCAGCCCACATACAAATTGTGCATCTTAAAAATACCCATCAGCCATGTCCGTACTGTGGAAAGTTCCTGGCTTCTGCTCATATGGGAGAGCACTTGAAGAAGCATGAATTCGAAACTGTGTTTACATGTGAATACTGTGGGATAGTCTTGAAAACGAAATTAGGTTATGTTCAGCACACACGTCTACACACTGGAGAGAAACCGTACCCATGCCAATATTGCAGTGAAACCTTCTCCGCATCCTCCAGAAGATCAGAACATATACGGAAGCTACACAAACGCAAAGAAGTGGTTTTAAAGTATGCATGTGAATACTGCCCAGCGAGATTCCAACTGCCGTACAAACTTAGGAATCATGTGTCTACGGTTCATAACAAAGATATCACATCTTCGGTGCCATTTTCTTGTAAGATATGCCTGGAGAAGTTCAGCAGTTGCAGAGGTCTGACGCATCACAGTAGGAAACATCAAAAACAAGGGAATATGAACTTTAAAGTTTACAGTCAACCGGTTGCTCGCGAAGAACATGTCGAGAGCTCGCCCCTGCTGCCAAACAGAATATGCGAAGGCTGTTCCGCCGCCATTGCACCTACCATAAACCTCATTCTGCACCTCAGGGAGGTGGACAGGAAATGGAGAGACGCAACAGACTACCTAGACCAACTAGAAGTCAAAGACAGCACCAAAACTGTCTATATAGCCATAGACGCCCAAGCCAAAGACTTGACAACGTACACAGACAATGTCAAGCGGGAAGAAAAACTCATAGACAAGACAGAGGTTATGAGATGCTTCAAGAAAAGGAAGTCCCAACAAAATGCTATCAATAGGAGGAATGAATTGGAAAGGAAATTGCGTGATTCGGAAATCGTTACAAATATGAAATGTCCCGAGTGTGAGAAGTCTTTTCTCTGCATCTACAAGTTTAATATTCACATGCGGTATTATGGGAAGCGCGCGTGCGTGCATTGCAGGAAAATGGTCGATGTAGAGAAACTTAAAGATCATTATGTTAGCCATGGTATTGATACGATGCAGTGCGACATATGCTTCGACACTTTTAAGAAGATTGAGGCGTATTTGAAACACAAAATAACTTACCATAGCAAGGGGCCGTATTTTTGTTACATCTGCAAGCTTTCGTACAGGGATTCACATCATCTTGCTTCGCATATGACAAGCAAGCATGAGCCAAGATTCTGTCTTGGTTGCAATCGCAAATTCTCCAACGTGTACTGTTTCAGAACGCACTCTAGGAAATGTAGCAATGCCAAAAAAAAGGCTGGCGTCTTCATTTGTGACATTTGTTCTAAAGTTTATGGCTCCAAATACGCTTTGAAAGTGCATTTGGAATACATACATATGAATAAAGAGCATACGCATCAATGTGAACACTGTGGTAAAGTGTTTAACAGTGCTATACATCTTTTGGAACACAGCAACACGCATAACAGGGTTCCGGATAGATTTGTTTGTAACATTTGTAACATGCCTATGAGTACTAGACGAGGGTACCAAAGACACTACAATAGACATATTAAGAACCCAAATTACACTCCAAAGAGGCCCAGAGCTCCAAATGCTGAGGTCGCCGAGGACTCCACTCTACCACAAGGACTGTGCCGAGCCTGTTCGGAAGACGCCATCGCAGCAGCGCAGTTCAGGCAACTCAGCGCCACCTCGCATCAGCAGTGGAACCAAACCGTCGAAATACTCGCCCTCGCCCAAGACCCTGACAGCCAAAACAGAACCCTGTACGTCTTCTACAACGGAGAAAACACCGTTTTCAGGGAGGATATTGAAGCGGTCACCAAAGATGACGTCGTCGAACATCTCAATAAACCTAAAAAACCTGTCAAAGTCAGAAGAGCATATTCTAAGTCGACTGGCAAATGCCAATGTCCTGATTGCGGAAAGGACTTCCCAGTTGCATATAACTTGAATGTGCACTTGAAGAATACTATGAGAAGGGCGTGTGTTAGATGCGGTAAGGTGTTAGAAAGGGAGAAGTTGGCTGAACACTTGGCTAAAGTCCATGGGAAGCTGCTTGCCGACTGCGAGGTGTGCTATAAGCTTTTTGAAACCGAAGAGGGATTAAAGCAGCATTATTTGAGCCACCATAGTCGGTTTTCTTTCGGTTGCCAGATATGTGGACGAGGGTACACCAATGACAGAGCGCTACGAGCGCACATGTACGCTCATACGTTGTTCCACTGCGTGTCGTGCAATCTAAGCTTTGAGAATAGACGCTGCTTTAAACATCACCAAAAGAAATGCCAGAGTGATCGTCAGCCGACAGCTACAACGTTCGCATGCGATTACTGCGGTAGCGTGTACAATAAGAAACCGTCGTTGCGCATACACATCATACAAAAACATCTTAACGTACTTCCTTACGTTTGCGAAACGTGCGGCAAAAGAACCTCCACGTTAGCACACTTGCGATCCCACGAAACTATCCACACAACCGAGCGGAAACTGTATAAGTGCTCGTGTGGTGCTGAAATGCGTACGGAATTGGGATATCATTTGCATCAGAGAATCCACACTGGGGAGAAGCCTTACGAATGCGAAGAATGCGGTGACAGGTTCCTCTCCGCCTCGAGACGTCTTGACCATATTAAGAGAAGGCATAGAAGTGCGAAAGATATGCCCCATGGTTGTGAAATGTGCCACGCGCGATTTGTAGAGGAAGAGCCCCTCTGCCCCAACGGCGTCTGTGCAAATTGCACCAGCCACGCTATCGCTGTTCAAGAGTTCAGGTCCCTGGTCACAGACTCCTGCAAAATCTGGTCTTATGCTGTCCACCAGCTTGAGATCATACCTCACAACGACGCTCCATCCGTCAAATCCCTCTGTGCCTTTCTGAGAGCTGACAACCTCAACATCCAAATAGCCAAAGACTACACAAACAATGAGAAGACGACGCCTTTGATCCGACTAAAAACAAGAATGAACCGGAAGAAAAGCGAAGAGAAGAAACCAAGGGTACACAGGGCGGGGCCTCCCTGTAAATGTCCGGATTGCGGAAAAGAATTTATAAGTCCGTATTATTTAAACGTTCATTTCAAAAACAGCGGCCAAAAAGATGTTTGCATCACTTGTGGCGCTGTGTTGCTTCGCGGAAAACAAATGAGGGACCATTTAGTAAGAGTGCATAGAGAGAACGCGTTTTTGTGTAAAGAGTGCCCGGCTTTGTTCTCCAATGAAATTGACGCTAAAAACCACGATAAAAAAGCTCATAAGAATGGCCTTACCTGCGGGGATTGTGGACGGACGTTCCTTAGAACCAATTCCTTTGAATCCCACTCCCAAATGCACGCTGTACGGACGTGCAGATCATGCGGGATCCAATTTACCAATCGGGCGTGTTATAGAGAACATCGATCGACATGCGAGCCAGATGCGAAACCGGATAGAGACACAGTGCCTCGGAATAGGCGATCTAACATACGAGATCCAGCTACGTTCACTTGCGATTATTGCAAAAAGACTTATACGTCTCGTCCTCAGCTCAAAAATCACATACTATGGATACATATGGACGTTAGACCCCATCAGTGTCAATGGTGCGGTAAACGATTCTATACTCCGGCTCGCTTGGCTGAGCATAGCGTGGTGCATACAAGAGAGCGCAACTTTGGTTGTGATATTTGCGGCGCCAAATTAGTTTCTAAAATGGCTGCCGTGTACCATAGAAGAAGGCACACTGGGGAAAAGCCTTACACTTGCGAAGATTGCGGTGATTGTTTCATATCTGCCTCGAGAAGGACGGAGCATGCGAAGAGAAAGCATGGCAAAGGGCCCAGGGTCCATTGCATGCAGTGCCCATCGACCTTTGTTAGGATTCATGAACTGAAGAAGCATATTGAGAAGGCacataatactaatattatttcttTGCTGGATGATTGA
Protein Sequence: MNRQVDIKALVSHIVRGDGLDKCRICMGDTTEGQVYLGDTVMMDGERPVTLAELLEIITGIEVHTEEDLPSGLCTVCTERAMEAANFRNQCRQAVNQWESTLQLLNNTPIKDKFLKKMFIIVEKDQIVMVDSLKDFNRTQLAAERRSSRVQKFKRRSAREGKHKCQCTDCGKKFAYAQHLYLHLKESTDFKRACYICAQIMTRDALILHLNKVHKLETFDCKKCPALVRSEKLLAKHMEEAHSSGACTCGDCGRSFKSKPAFHAHISIHTVKTCPGCDKVFRNQTCYLYHVKKCCNLDSSRKTHWTKNKVMIEVKNKNSERRTKVGLRGAADKECICDYCGKKLAGKKFIAAHIQIVHLKNTHQPCPYCGKFLASAHMGEHLKKHEFETVFTCEYCGIVLKTKLGYVQHTRLHTGEKPYPCQYCSETFSASSRRSEHIRKLHKRKEVVLKYACEYCPARFQLPYKLRNHVSTVHNKDITSSVPFSCKICLEKFSSCRGLTHHSRKHQKQGNMNFKVYSQPVAREEHVESSPLLPNRICEGCSAAIAPTINLILHLREVDRKWRDATDYLDQLEVKDSTKTVYIAIDAQAKDLTTYTDNVKREEKLIDKTEVMRCFKKRKSQQNAINRRNELERKLRDSEIVTNMKCPECEKSFLCIYKFNIHMRYYGKRACVHCRKMVDVEKLKDHYVSHGIDTMQCDICFDTFKKIEAYLKHKITYHSKGPYFCYICKLSYRDSHHLASHMTSKHEPRFCLGCNRKFSNVYCFRTHSRKCSNAKKKAGVFICDICSKVYGSKYALKVHLEYIHMNKEHTHQCEHCGKVFNSAIHLLEHSNTHNRVPDRFVCNICNMPMSTRRGYQRHYNRHIKNPNYTPKRPRAPNAEVAEDSTLPQGLCRACSEDAIAAAQFRQLSATSHQQWNQTVEILALAQDPDSQNRTLYVFYNGENTVFREDIEAVTKDDVVEHLNKPKKPVKVRRAYSKSTGKCQCPDCGKDFPVAYNLNVHLKNTMRRACVRCGKVLEREKLAEHLAKVHGKLLADCEVCYKLFETEEGLKQHYLSHHSRFSFGCQICGRGYTNDRALRAHMYAHTLFHCVSCNLSFENRRCFKHHQKKCQSDRQPTATTFACDYCGSVYNKKPSLRIHIIQKHLNVLPYVCETCGKRTSTLAHLRSHETIHTTERKLYKCSCGAEMRTELGYHLHQRIHTGEKPYECEECGDRFLSASRRLDHIKRRHRSAKDMPHGCEMCHARFVEEEPLCPNGVCANCTSHAIAVQEFRSLVTDSCKIWSYAVHQLEIIPHNDAPSVKSLCAFLRADNLNIQIAKDYTNNEKTTPLIRLKTRMNRKKSEEKKPRVHRAGPPCKCPDCGKEFISPYYLNVHFKNSGQKDVCITCGAVLLRGKQMRDHLVRVHRENAFLCKECPALFSNEIDAKNHDKKAHKNGLTCGDCGRTFLRTNSFESHSQMHAVRTCRSCGIQFTNRACYREHRSTCEPDAKPDRDTVPRNRRSNIRDPATFTCDYCKKTYTSRPQLKNHILWIHMDVRPHQCQWCGKRFYTPARLAEHSVVHTRERNFGCDICGAKLVSKMAAVYHRRRHTGEKPYTCEDCGDCFISASRRTEHAKRKHGKGPRVHCMQCPSTFVRIHELKKHIEKAHNTNIISLLDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -