Afla003448.1
Basic Information
- Insect
- Achlya flavicornis
- Gene Symbol
- -
- Assembly
- GCA_947623365.1
- Location
- OX392496.1:7171421-7181930[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.034 2.2 9.2 0.8 1 23 458 480 458 480 0.97 2 12 0.37 24 6.0 4.0 1 23 487 509 487 509 0.96 3 12 0.37 24 6.0 3.7 1 23 513 535 513 535 0.96 4 12 0.0041 0.27 12.1 3.4 1 23 540 563 540 563 0.96 5 12 0.43 28 5.8 0.2 2 19 571 588 570 593 0.89 6 12 8.9 5.7e+02 1.6 2.7 3 20 603 620 601 622 0.91 7 12 0.086 5.5 8.0 0.1 2 19 632 649 631 651 0.93 8 12 0.058 3.7 8.5 5.9 1 21 660 680 660 682 0.94 9 12 0.0034 0.22 12.4 0.1 3 23 712 733 710 733 0.93 10 12 0.00012 0.008 16.9 1.3 1 23 739 761 739 761 0.98 11 12 9.8e-06 0.00063 20.4 0.3 1 23 767 789 767 789 0.94 12 12 0.00034 0.022 15.5 3.3 1 23 795 818 795 818 0.97
Sequence Information
- Coding Sequence
- ATGGCTCTTGCAATTAATATTGTAAAGAAGACCAAAACATCCTCGTTGCGCGTGTGTCGAGGATGTCTCGCTACAGACGCACGACTGTACGACATGCGCCAGGACCGACTGCTGGAGGCCTATAACATACTAATGAGTAGTGCTGTACAAGTATCAGATGACCTGCCACATTACTTATGCAGCTACTGCGCTGTACTGCTGCTCAAGTGCGACACATTCAGAACAAAGTGCATAGATACACTAATAGTGCTTAGAAATGCTCAACAGCAACATATAGATATTGCTGCAGAACAAATAAATAATGTAGGCCAACCTAAGTACTTCAAAAAAATTATATATAACAATATAAATATATTTGATAAAACTCTTAAACGCAACCATTCTGATATATCTACTAATATATATGATACATCTTCAGAATCTGATATATCTTTGGATTCTGATATATCTTTAGATTCTGATGAATCTTTAGATTATGATTTAAGTGAAAACTCTGATAGCTCTGATAGTGATGTAAACAAAACTCATTTAAAAGCCAAATCAAATTTTAGAAAACATAACATATATCACAAAGAACATGACTATGCTGCAAATAATTCTATAAATGATATTAAAAGCCTACTTAAGAACTACTTTGATACTGAAAGAATTGGATTATTAAAAGACTTTAAGGTAAACTTAGATTGTGAAGAAATTAAAGGTATAAGTAACATAAGAGACCATCATATGCATCAGTTGTCAGAAATTATTAATCATATTCAGTATTCTAGTGAGAGAAGTAATGAATTACTAAAGATTTTAGATGAAGATACACCAAATTGTAAAAATAATGCCTCAAAATCTGTAGCCACCAATAAAAAAACTAGAATTATAAAACAAGAATCCAAGTCTAATGCAAAAGCTCAAACTACAAATAAAGAGGAAGTCGTTCAAACAGGTAAAGAACATGAACAAAAGGACATGGTAGAAGAGAATACAAATATATCACTATTAGAAAGACATATTGATATTAAACCAATCGTCAAGGATTTTATTAAAACTGATGAAGTAAAATTAGAAGTATCAAAATATGAAACTAACGAAAGTGAAATCCAATTTGATGAAATAAACGAAACGTTGGACTCGGAAGACGACATTGCTACTGAAGACTCAAAACTGGATTCTAAGCCATCGAATTATAAACAAAAAGGTGCAAATTATGGAGGATGTAAAAGTATCATCAATACACTATTAAAAGGACGCGACACAAAGAAAAAGATAACGGATGAGATCTATAGAATGTATAACACAGAGGTAAGACACCTAAGTAAAGAAGAACAAATAAATGAAATTAATAAACGGAAGCAGTCTGAGAATTATAAAAATGGACAGTTCAAATGCGACATTTGCTTCAAAGGGTTCCTTACTGATGAAACCTATATGAATCACATGTTGCTACATGATGATGTCAGCGGCAAGTTCGTGTGTGACATCTGTCAGTGTCACTTCATGACAAGCAAGAGGCTCATCGGACACAAGAAAGGTCACGCTAAACTATTTATTTGCAAAGAATGCGGACACACCACGTGCCATGCCACTCTAGCAGCCGAGCATTATAAATGGCACATTGGAAAGAAATTCTCCTGCGAGACTTGCGGGAAAGAATTTAAAAAAAATTCAAGTAAATACGGACACATTAAGGTGTGCCACCCGACCAGTGAACAGTTGGTGCGTTGTGAGATCTGCGGAGACTCATTCAATGGTCCCTTTGGACTCAAATATCATGATAATAGGTCACATAAAGAGATGTACTCCCCGGAGTGTCTATGTTCTGGTTGCGACACTCAGTTCTACTGCTCGGACGCGTTTAAGGCGCATCGAGGAACCGACGGACTGTGCGACACGCTACACAAGTATTGTGTGCGCTGCGGTATGTCGTTTGAGACTGAACAACTGCTGAAGGAACATGAGATAGAGCAACGGAAACCAAAGAATGATTTTGATTGCGAAGTGTGCCACAAGAAATTCAAATTATTCTGGAAATTAAAAGCGCACCAGAGATGTCACTCCGCCACGTATCCTAATTACATGAAATTGTATAACGCGAGAAGTTCTATGAGAGATAAAGAGAAATATGGGAATGAGGCTATGATATGTGAAGTGTGCGGGAAGAAACTGAAGAATACTGGTCTACTTAAAGTACATTACAGTTTGGTGCATTCAAGTGACAAGCCATTTAAATGTAACCTCTGTTCTAAAGCGTTCAAAACATCTTCTATATTGGTGAATCATAAGAGAGTACACACGGGAGAGCGTCCGTTCCAATGCCAGATTTGCCCAAAAGCGTTCCAGAACCCACAAAACCTTAAACGACATAACGTTGTACACACAGGAGAGCGTCCACACTCATGTGACGTCTGTGGGAAGAACTTCCAAACTAAGGGTTGCGTGCAGACGCACATTAAAACAGTTCACATGAAGATACCCATGCCGCCGAGGATCCGGCGGAGGAACAAGAAAACTGAATGA
- Protein Sequence
- MALAINIVKKTKTSSLRVCRGCLATDARLYDMRQDRLLEAYNILMSSAVQVSDDLPHYLCSYCAVLLLKCDTFRTKCIDTLIVLRNAQQQHIDIAAEQINNVGQPKYFKKIIYNNINIFDKTLKRNHSDISTNIYDTSSESDISLDSDISLDSDESLDYDLSENSDSSDSDVNKTHLKAKSNFRKHNIYHKEHDYAANNSINDIKSLLKNYFDTERIGLLKDFKVNLDCEEIKGISNIRDHHMHQLSEIINHIQYSSERSNELLKILDEDTPNCKNNASKSVATNKKTRIIKQESKSNAKAQTTNKEEVVQTGKEHEQKDMVEENTNISLLERHIDIKPIVKDFIKTDEVKLEVSKYETNESEIQFDEINETLDSEDDIATEDSKLDSKPSNYKQKGANYGGCKSIINTLLKGRDTKKKITDEIYRMYNTEVRHLSKEEQINEINKRKQSENYKNGQFKCDICFKGFLTDETYMNHMLLHDDVSGKFVCDICQCHFMTSKRLIGHKKGHAKLFICKECGHTTCHATLAAEHYKWHIGKKFSCETCGKEFKKNSSKYGHIKVCHPTSEQLVRCEICGDSFNGPFGLKYHDNRSHKEMYSPECLCSGCDTQFYCSDAFKAHRGTDGLCDTLHKYCVRCGMSFETEQLLKEHEIEQRKPKNDFDCEVCHKKFKLFWKLKAHQRCHSATYPNYMKLYNARSSMRDKEKYGNEAMICEVCGKKLKNTGLLKVHYSLVHSSDKPFKCNLCSKAFKTSSILVNHKRVHTGERPFQCQICPKAFQNPQNLKRHNVVHTGERPHSCDVCGKNFQTKGCVQTHIKTVHMKIPMPPRIRRRNKKTE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01252203;
- 90% Identity
- -
- 80% Identity
- -