Basic Information

Insect: Achlya flavicornis
Gene Symbol: THAP3
Assembly: GCA_947623365.1
Location: OX392496.1:5815203-5831660[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.12 8 7.5 0.6 1 23 362 384 362 384 0.95

2 11 0.028 1.8 9.5 0.8 1 23 391 414 391 414 0.93

3 11 1.2 76 4.4 0.2 1 23 418 440 418 440 0.90

4 11 0.0046 0.3 12.0 1.0 1 23 445 468 445 468 0.98

5 11 0.0031 0.2 12.5 0.7 1 23 472 495 472 495 0.96

6 11 1.9 1.2e+02 3.8 0.1 2 21 508 527 508 528 0.85

7 11 0.17 11 7.1 0.1 2 23 585 607 584 607 0.96

8 11 0.01 0.66 10.9 0.5 2 20 623 641 622 644 0.92

9 11 8.2e-06 0.00053 20.6 2.0 1 23 650 672 650 672 0.99

10 11 0.00026 0.017 15.9 2.8 1 23 679 701 679 701 0.98

11 11 0.00013 0.0084 16.9 3.0 1 23 707 730 707 730 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.12	8	7.5	0.6	1	23	362	384	362	384	0.95
2	11	0.028	1.8	9.5	0.8	1	23	391	414	391	414	0.93
3	11	1.2	76	4.4	0.2	1	23	418	440	418	440	0.90
4	11	0.0046	0.3	12.0	1.0	1	23	445	468	445	468	0.98
5	11	0.0031	0.2	12.5	0.7	1	23	472	495	472	495	0.96
6	11	1.9	1.2e+02	3.8	0.1	2	21	508	527	508	528	0.85
7	11	0.17	11	7.1	0.1	2	23	585	607	584	607	0.96
8	11	0.01	0.66	10.9	0.5	2	20	623	641	622	644	0.92
9	11	8.2e-06	0.00053	20.6	2.0	1	23	650	672	650	672	0.99
10	11	0.00026	0.017	15.9	2.8	1	23	679	701	679	701	0.98
11	11	0.00013	0.0084	16.9	3.0	1	23	707	730	707	730	0.93

Sequence Information

Coding Sequence: ATGAGGTGCAGTGTTCAGAATTGTACAAATGATACAAGGCGAACAACTAAAAGCCATGGAATCACATTTCACATGTTCCCAAAAGAACCCAAGCTCAGGTCTGAATGGGTGCAAGCCCTTGGCATGGCAGACTGGGAGCCAAAGGACAGGAGCACCATCTGCTCAGAACACTTCCGTAATGATGACTTCTATCAGACCAAATGTGGATTACGGAAGATTAAAAAGAGAGCTGTACCGGTTGTGTCGCAAGACTCTGCCGAAGATCTGGATGCACCTGCAACATTAAGGGTATGCAGGATATGCCTAGCCATGGACATGAAGATGTACAACATCAGAGAGTACAAACTGGAACATACGTTTCAACAAATCATTAGCCAAGAGATGAGTGATGAAGACAGACTGCCACAGAAGCTATGTTGGGAGTGTGGACACAGGCTGGCGAGCTGGTCTCGCTTCAGGAGCAAGGCGCTCCGCACTCACAGGCTCATGCTGGACATGGTGCATGGGGGACGATATATAACAGTGCGAGACATAAAATCAGTAAACCGAACACACAATGAACTAAAATCAACTTTAATACAAAAGATATATGAACCAAATGACTGTGACATGGAAATAATAGATGACCAAGTCTTCGTTAAATCTGAAGTCGATAAAATTGTTGATTCAGACATTCCCATAGATATAGATGATGAATTCAAACTAGAAACAGATATACCACAAATAGCAGAAGTAGAGGTGAAAGATGAGAGCAACGAGATATATTTCGATGAATTCATAGACAATTTTGAAGATACAGACGACGATAAGAAGCTTAGTGAAGTGTTTGTGAAACCAAAGACTAAAGTTAAGAAGAAGAAGTTGAAAATTATTAAGAAGGTTAAAGTTAAGACTGCTAAGAAGAAGGAGGAAGACGATAGTCCCTCTACAACTATGGATAAGTACAAAAAATCCGATGTTAGACGTAGAAAAACAAACGATGGACTCGACGAATCCCTCTTCACAATAACAACTCTAACATACGAGGAGCAAATATCAGAGATACAGAAGCGGCAAGAGGCAAATGGGTACAAGAGTGCGCCCTACAAGTGCACGGTCTGCTTTAGAGCATTCCAGATCAAGGATCGATATGACGCCCATATTGTTAGGCATAGCGAGGCGAGCGGTGCGTACGAGTGTTTCATATGTAAGACTCGTTTAAAGACTGGTAGAGCTCTCAGGAAACATCTGACGGCACAACACACTGAGAAATTTAGCTGTAAAGGATGTCCCTTCATTACTAGAAATAGGGGTGTGGCGAGAGAACATGAGAAATGGCACGCGGGAACGAAATATCAGTGTCCACATTGTCCAAGCGAGTTCGATAAACTGACGACTTACATGGGCCACATACGCATCAAGCACGTGTCGGACTTCGTGTGCGAACTGTGCGGCTACACTTTCGTCAGCAAGAAGGGCATCGACGTGCACAAGAAGAAGAAACATCGACTCGTTGATAAAGCTATGAATATTGAAGGTCCGTACTGCGAGGTGTGTGACGTACGGTTTATATCTGAAGAGGCACATGCTAGACATCTCAAGCTATCATCCAGACACAGTAGCGATAATGATCCTAACCGCATAAGAAACGACTCTCAGAGCATGAACGCTGAGAAGAATGGCCGAGTCATGAGGAAGATTGAACGCAGGCCGGTCATACACCCCAGGGAACCCGCCGACCCGGCCATGAAGCAGGATAATACTGGACCAGTACCCTGCGAACAGTGTGGTCTACAACTCCGTGACTTACGCTTATACGCGCAACACTTTAGAAGAGCGCACCCAGACAAGAATCGAACCAAGTACCCCGCGATGAAGACGCCGTGCATGTGTGAACAGTGTGGACGGATATTCCAGAGCATGGCCCTGCTAAAAGACCACATGTGGGTGCACACGGGCGAGAAGCGGTTCAAGTGCGACCGCTGCCCCAAGAGCTTCACGCAGAAGACCAACCTGGTGTTCCACATGCGCGTGCACAGCGCGCAGCGCCCCTCCTACGAGTGCCCGCTCTGCGGGAAGCACTTTGCCTTCTTTAACAACAGGCGGAGGCATATGTTCATCCACACAGGGCTGAAGCCCTTCAAATGCGACACGTGTGGCAAGTGCTTCACGACCTCGGGCGAGCAGCGCGCGCACGTCGAACACGTGCACCTCAAGAAGCCGTGGCCCAAGCGCGCCCGCGCGAGGCACGACAACACTAACGTGCACACTGACGCTTGGGATAAGTGTGCCAGTGAAGATTAG
Protein Sequence: MRCSVQNCTNDTRRTTKSHGITFHMFPKEPKLRSEWVQALGMADWEPKDRSTICSEHFRNDDFYQTKCGLRKIKKRAVPVVSQDSAEDLDAPATLRVCRICLAMDMKMYNIREYKLEHTFQQIISQEMSDEDRLPQKLCWECGHRLASWSRFRSKALRTHRLMLDMVHGGRYITVRDIKSVNRTHNELKSTLIQKIYEPNDCDMEIIDDQVFVKSEVDKIVDSDIPIDIDDEFKLETDIPQIAEVEVKDESNEIYFDEFIDNFEDTDDDKKLSEVFVKPKTKVKKKKLKIIKKVKVKTAKKKEEDDSPSTTMDKYKKSDVRRRKTNDGLDESLFTITTLTYEEQISEIQKRQEANGYKSAPYKCTVCFRAFQIKDRYDAHIVRHSEASGAYECFICKTRLKTGRALRKHLTAQHTEKFSCKGCPFITRNRGVAREHEKWHAGTKYQCPHCPSEFDKLTTYMGHIRIKHVSDFVCELCGYTFVSKKGIDVHKKKKHRLVDKAMNIEGPYCEVCDVRFISEEAHARHLKLSSRHSSDNDPNRIRNDSQSMNAEKNGRVMRKIERRPVIHPREPADPAMKQDNTGPVPCEQCGLQLRDLRLYAQHFRRAHPDKNRTKYPAMKTPCMCEQCGRIFQSMALLKDHMWVHTGEKRFKCDRCPKSFTQKTNLVFHMRVHSAQRPSYECPLCGKHFAFFNNRRRHMFIHTGLKPFKCDTCGKCFTTSGEQRAHVEHVHLKKPWPKRARARHDNTNVHTDAWDKCASED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01417220;
90% Identity: iTF_01416274;
80% Identity: iTF_00007152;