Basic Information

Gene Symbol
ZBTB41
Assembly
GCA_947623365.1
Location
OX392496.1:7102559-7114057[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.19 12 6.9 0.8 1 23 418 440 418 440 0.91
2 12 0.1 6.5 7.8 6.5 1 23 447 469 447 469 0.98
3 12 0.66 42 5.2 0.3 1 11 473 483 473 495 0.79
4 12 0.027 1.7 9.6 4.6 1 23 500 523 500 523 0.93
5 12 0.23 15 6.6 0.2 2 19 531 548 530 553 0.88
6 12 3.1 2e+02 3.1 3.3 2 20 562 580 561 582 0.90
7 12 0.05 3.2 8.7 0.1 2 19 592 609 591 611 0.93
8 12 0.004 0.25 12.2 7.8 1 21 620 640 620 642 0.96
9 12 0.02 1.3 10.0 0.0 3 23 672 693 670 693 0.90
10 12 2.9e-06 0.00019 22.1 2.1 1 23 699 721 699 721 0.99
11 12 5.1e-05 0.0033 18.1 0.5 1 23 727 749 727 749 0.97
12 12 1.2e-05 0.00075 20.2 0.9 1 23 755 778 755 778 0.97

Sequence Information

Coding Sequence
ATGAGCACAACATCCTGGTTGCGAGTGTGTCGAGGATGTCTCGCTACAGACGCACGACTGTACGACATGCGCCAGGACCGACTGATGGAGGCCTACAACACATTATTGAGTACCGCTGTACAAGTAACAGATGACCTGCCACATTACTTATGCAGCTACTGTGCTGCACTGCTGCTCAAGTGTGACACGTTCAGAACAAAGTGCATAGATTCACTAATAGTGCTTAGAAATGCTAAAAGCCAACATTTAAATATAAAAGAAGAATATTTGTTGCAGCTTACTTCAGAACATATGAAAATAATGGACGGAACTACATACTTGAAACAATCTGAATTAGTACATATGAGTTATGTTGATGATACTCCTAAACAGAACGATTCTGATACATATTCAGATTCTGATGATTCTATAGATTCTGATTGTTCAGTTAGTAAAAACAAAATAAATGTAAATTTAAAATCCAAAGCCAAATCAATTATCAAAGAACATGACTATGCGATAACATTTTCAAATGATGATATTACAAAACTACTAAAGAAACATTTTGATGGTGAAAGATGTTTATTAAAAGACTTTAAAGTGAACATAGATTGTGAAGCAAGTGAAGATATAAAACACATTAGATACCATCAAATGCATCAGTTGTCTGAAATTATTAATCATACACAGTATTCTAGTGAGACAAGTACTGAATTACTGAAAATATTAGATGATGATATTCTAAAATGTAAAAATAAAACCTCGAAATCGAAGTCCAATCCAATACTTAAAACTGAAAATGGAGAGACGGTAGCTCATGTAGGCAAAGAGCATTTAAAACGGGACATAGTACAAAATAATACAAATAAATCAATAATAGAAATACATGTTGATGTTAAACCAGTAGTTGTTAACAGTGTAGATTTAAATGCAGAAATTCCTTGTTCGCTTCGAAATGACGAAATAAAAATAGAACTATCTCCAGATGAACTATTCGTCTTTGAAACTCATTGTGATGGAATAAATGAAACCTTAGACTCGGAAGAAGTTATTCCTATTCCAGACCAAAAAACCAACGCGAAAAAAATTGTACAAAATAAGAGTCGCTGTAAAAATATCAATGGAAAATTAAAAAAACGTCAACTTAAGTTGGAAAAAATTACCGCTGAGAAATTTGCAAAATATAACACAGAGGTAAGAAACCTAAGTAAAGAGGAACAAATTAAGGAAATTAATGATAGAAAGGAGTCTGATAATTATAAAAATGGACAGTTCAAATGCAACATTTGCTTTAAAGGATTCCTTATTGAAGAGACTTATAAGAATCACATGGTGCTACATGATGATTCCAGCGGCCAGTTCGTGTGTGAAATCTGTCAGTGCCGCTTCTTCACAAGGAAGACTTGGAAGGGTCACCATAGGAGCCACGGTAGAGTATTTACTTGCAAAGAATGTGGATACACTACGAAGATAGGAGTAGCAGCAGTTGAACATTATAAATGGCACAAAGGAAACACGCACTCCTGCGACTATTGTGGGAAAGAATTCCGAAAATTGTCAAGTAAATACGGACACATCAAATGGTGTCACCCGACCAGTGAACAGCTGGTGCGCTGCGAGATATGTGAAGACTCTTTCAATGGACTATCGGGCCTCCAAAAACATGATAAGAAGGCTCATAAAGAGATGTTTTCACCGGAGTGTCGATGTTCTGGTTGCGACACTCAGTTCTACTGCTCGGACGCGTTTAAGGCGCATCGAGGAACCGACGGACTGTGCGACACGCTACACAAGTATTGTGTGCGCTGCGGTATGTCGTTTGAGACTGAAGAACTGCTGAAGGAACATGAAATAGAGCAACGGAAACTACTGAGTCAATATAAATGTGACGTGTGCCATAAAACGTTCCAACAATTTTCTAAATTGAAATTGCACCAGAGATGTCACTTGGCCACGTTTCCTGATTTTATTAAAAATTATTACGCGAAAAAAATGGTCAAGTACGGGACAAAACAGCGCGGGAGGGAAGTCATATGTGACGTGTGCGGGAAGTCAGTGTTGAGTCCTGCTAATCTAAAACAACATTACTTTTTGGTTCACTCTACGGAGAAGCCATTCAAATGTACCGTTTGTCATAAGGGATTCAAAACATCTGCTGTGTTGATGACTCACATGCGTGTACACACGGGTGAACGCCCGTTTCAATGCCAGAATTGTCCGAAAGCGTTTCAGAGTAAACCAAACCTTTTGCGACATAACCTGGTACACACAGGGGAGCGTCCGCACTCTTGCGATGTCTGCGGGAAGACTTTTCAAACTAAGGGTTCGGTCAAGATTCACATACAAACGGTACACATGAAGATACCCATGCCGCCGAGGATTCGCAATAGGAAGAAAACTAAACAATTGTAA
Protein Sequence
MSTTSWLRVCRGCLATDARLYDMRQDRLMEAYNTLLSTAVQVTDDLPHYLCSYCAALLLKCDTFRTKCIDSLIVLRNAKSQHLNIKEEYLLQLTSEHMKIMDGTTYLKQSELVHMSYVDDTPKQNDSDTYSDSDDSIDSDCSVSKNKINVNLKSKAKSIIKEHDYAITFSNDDITKLLKKHFDGERCLLKDFKVNIDCEASEDIKHIRYHQMHQLSEIINHTQYSSETSTELLKILDDDILKCKNKTSKSKSNPILKTENGETVAHVGKEHLKRDIVQNNTNKSIIEIHVDVKPVVVNSVDLNAEIPCSLRNDEIKIELSPDELFVFETHCDGINETLDSEEVIPIPDQKTNAKKIVQNKSRCKNINGKLKKRQLKLEKITAEKFAKYNTEVRNLSKEEQIKEINDRKESDNYKNGQFKCNICFKGFLIEETYKNHMVLHDDSSGQFVCEICQCRFFTRKTWKGHHRSHGRVFTCKECGYTTKIGVAAVEHYKWHKGNTHSCDYCGKEFRKLSSKYGHIKWCHPTSEQLVRCEICEDSFNGLSGLQKHDKKAHKEMFSPECRCSGCDTQFYCSDAFKAHRGTDGLCDTLHKYCVRCGMSFETEELLKEHEIEQRKLLSQYKCDVCHKTFQQFSKLKLHQRCHLATFPDFIKNYYAKKMVKYGTKQRGREVICDVCGKSVLSPANLKQHYFLVHSTEKPFKCTVCHKGFKTSAVLMTHMRVHTGERPFQCQNCPKAFQSKPNLLRHNLVHTGERPHSCDVCGKTFQTKGSVKIHIQTVHMKIPMPPRIRNRKKTKQL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01252217;
90% Identity
-
80% Identity
-