Basic Information

Insect: Achlya flavicornis
Gene Symbol: ZEB2
Assembly: GCA_947623365.1
Location: OX392480.1:2075386-2086363[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 4.8 3.1e+02 2.5 0.3 2 23 6 27 5 27 0.95

2 13 0.015 0.97 10.4 0.2 1 23 1013 1036 1013 1036 0.93

3 13 1.7e-05 0.0011 19.6 1.7 2 23 1151 1172 1150 1172 0.97

4 13 0.00018 0.011 16.4 2.5 1 23 1178 1200 1178 1200 0.98

5 13 0.0043 0.27 12.1 2.6 2 23 1207 1228 1206 1229 0.94

6 13 0.33 21 6.1 0.8 5 23 1242 1260 1241 1260 0.96

7 13 0.0076 0.49 11.3 1.6 3 23 1267 1288 1266 1288 0.96

8 13 0.0062 0.4 11.6 0.1 2 23 1305 1325 1304 1325 0.97

9 13 0.004 0.25 12.2 0.6 3 20 1333 1350 1331 1353 0.85

10 13 0.00099 0.063 14.1 0.4 1 23 1361 1383 1361 1383 0.98

11 13 0.0059 0.38 11.7 7.2 1 23 1389 1411 1389 1411 0.98

12 13 6.8e-06 0.00044 20.9 1.3 1 23 1417 1441 1417 1441 0.98

13 13 0.0011 0.069 14.0 5.1 1 23 1447 1469 1447 1470 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	4.8	3.1e+02	2.5	0.3	2	23	6	27	5	27	0.95
2	13	0.015	0.97	10.4	0.2	1	23	1013	1036	1013	1036	0.93
3	13	1.7e-05	0.0011	19.6	1.7	2	23	1151	1172	1150	1172	0.97
4	13	0.00018	0.011	16.4	2.5	1	23	1178	1200	1178	1200	0.98
5	13	0.0043	0.27	12.1	2.6	2	23	1207	1228	1206	1229	0.94
6	13	0.33	21	6.1	0.8	5	23	1242	1260	1241	1260	0.96
7	13	0.0076	0.49	11.3	1.6	3	23	1267	1288	1266	1288	0.96
8	13	0.0062	0.4	11.6	0.1	2	23	1305	1325	1304	1325	0.97
9	13	0.004	0.25	12.2	0.6	3	20	1333	1350	1331	1353	0.85
10	13	0.00099	0.063	14.1	0.4	1	23	1361	1383	1361	1383	0.98
11	13	0.0059	0.38	11.7	7.2	1	23	1389	1411	1389	1411	0.98
12	13	6.8e-06	0.00044	20.9	1.3	1	23	1417	1441	1417	1441	0.98
13	13	0.0011	0.069	14.0	5.1	1	23	1447	1469	1447	1470	0.95

Sequence Information

Coding Sequence: ATGGAACATCTAGTACAGTGCCCCGTTTGTACCCTCTACCTCCACAATGGGATGACCCTGGAGTCTCACCTTGACACACATCCCAAAGATCAAGTCATCAAGGCACTGTGCTGCCTGACAGCTAAGAGCAGTAGCTATGGAAGTAGAACATCAACACCCCTAAATTCAGAAAGGTCATACAGGAGCAGGTCTCGGACACCGGCAACAGATGATAGTGCACGATGGAATGGTTCCCACCGGAGTACAGAGCATGACAGATACTGGCGTAGAACACCAAGTAGAACACCCAGCAGAACACCTAGTAGAACTCCTAAAACAACGCCAGTGACAAACGTATCTAGGAATGCCACTCCAGACACTAGAATGACAGATATGAACTATGATAACTCTATCACAAATTCTGATCCGCAGTCGGCCACCTCTTTTGTTATGAAAAGTGATAAGACCCAGCAAACATACCAGCCGGCATCTCAACACACAGATTTTGATCCACAGTACATATACTATCAAGATCAGCAGGATGAGATTAAATATTCTCGCAGTGCTGAGTACAATGCACTAGATAATTCCAATAATATTTTTGCCTACAACATACCAACAGTGGGGACTGGGATGAAACTACAGCCAACTTTGATGTCAACTGCACCTAGGAAAGCCAATGATCTTGTTAAAATTTTGCCAAAACCTAATAATATACTTGTGAAACCTAATATGGGCGGTGTTCAATATCTAACTCCTGGGGTGAAGCCCTTGAATGTAGTGATGCCACCAGCACCGGCATTTGTTCAGAAGAATGTGCAGAATAATATGATAATGACTGGTAGTTTACCAACTGCTACTATGCAAATGGACACCAAAGGCATGCCTGCTCAGAAAGCTGCCAACCAGTTTAACCACTTAACCTCAGGTAGTTTCACACCAAGCACAACGGTTGTCACTCAAAACTCACATATAATTTATAGGGAAATGGTTCATAATTTAGATGGAAAGCCTTTTATATCGAGCATGCCAGCAGTTCTGGGTGGTCATGAGAATGTCACAAATGTTGCCCAGGCCAGCTCGATGTATCAGAATGTAATGGTGGTTGATCAGTTTGGGAATACTTCATGTATGTTTACAACACCTCAGCAACTTCTGCCCAAAGCTTGTCCCCCGCCTATGTTCAATGAAAACATGTTAGTAGGTACTGGAGCACACTTGGATAAGACTGTGCCAAACACAAGTGATACCAATAAAACTATAATGATCAAAGTCAGCCCAATAGTATCCTCAGACCCCATAGTTAGTTGTGAAACAGCATCTACTTCAATTCCACAAGCAAGTTGCTCATCAAGGGACAAAAAAGAAAAGCCTGTGGTCGAAAAGGGTGAACAGAAATGTGATACCCCAGGACCTAGTAAAGGTCTAAAGATTCTAAGTAATATAAAAGTGGAAGTTCCTGTACAGCACCATAAGAACATGGTGAATACAGTGATGGATCTTACTTGCTCTAATGACCCTGACTATTTGGAGCGCTCTGAATCACCAGAGAAGATCCTACCTGACTTAGATGATAACAAAACTATCATTTCAGATGATTGTACTCAGCCCTCAATATCAAGCAGTGATAGTGTAGTCTCTCATTCATTCTCTGTGATAAAAAATGTTGGTAATCCACCTTTGTACAAAGATTCTTCCAATAAATCAAATACTGTAGATAATAAAATGGAAACTGAGTTTGCAGATAGTTGTCCCGTGCCAGATCTAATATGCAATGAAAAGCCTTCAATATCACCTTGTAGCGAGTTGTCTGAGCACTGTGACAACTCTACTGATCGTACCCTTATATCACCCAAGCCTGAAAATAGTCAGCAATCACAAAATCCTCTAGACATTCACATTGACAAGAAACTTCAATTTTCAACCAAACCATTTAGGAATAATACTTTAAGACTGAACAATATTTACGTGAAAAAAAACAAAAAGGTATTACACATAAAAAATGCTAAAGCATCAAGCTCGACCGTTTCGAGTAAGGTGGAAACAGAGCCCATACCATCGTCATCAATTTGTAGATCACCTGAAAATTTTACTATGAATAAAAAACAAAAGGCAGATAGAAACGAGAAAAGGGACAAGTGTAGTGTTTTACAAACTGTATCAATTGAAATGGTAAAAGAGAATGATGATGAGCATAATAACTTTGATGCTGATACTGAGGAGCAGTCAATGGATATTGAGCCAATAGCACCTAATCAGAGTAATTCTAATGAGTATGCAACAACTGTCGACATGATACATGTCAAAGAGGAGGTAAACTCGAGCAACGAAGGGGTATTTAGCAACGAGGCGCCCGGCCGCGTCCTCACACCGTTAGAAACATTACGCCCTATCAATGTTATCACCTATGGAAGCATGTCCGCTGGTGATTTCGACGATGAATCCAACCATAGAGAGCTGCTAGATCTCGAAGCGGCGTCAAAAAATAAGCAATTTGTTAATATGATGAACGAGAATTATTTTGGGGATAACATTTATGCTGATTATTTCACGCCAGATAGAGTGGAAGCTTTCGACGCGGAAAGAGAGGCTTCGGCATTTAAAGAAGGATCTATAGGTATTTGGGGGGAGTCGTCGCAGAAGGAGACCGAGAGTGAGTTCGTGCTGCCGAATTTCATTCATGAGAGCTACAAGATAGCGGAGAGTACCGGGCTTGATTACTCGGATATTGGTGTTAGAGGGGGTGTAGGCGGGGAGGTGGAGGGGTGCGAGCGGGACAGCAAGGCGGATGTGCTGAGCGAGAGTAGAAGCGAGGGGGAGGCTCCGCTGAACATCTGCGCCGACGAGCGAATGCCGCCGCGCGGGGAGCTCAGCGGGCAGGAGAGCAACGGCGATATGGAGTCTTGGAGCGGGATGTACTCGGAGGTGACGCCAGCGGTGCCGTACGACCTGATGGCGCGCGAGAGCTGGGTCTCCGACGATTCTGAAATGGACGCCACTGAGAAACGGGAAGCTTTAGAGGAAGCGTTACACTTTCCGAAGAGTACACACAGGCAGTATACGTGCATGCAGTGCGGCGCCAAGTTCCCCTCTTTAAAGGAGATGCGAGCGCACAAGTCCCTTGCTCATGCGCCCGCGACCGCCACCTGTTCCGGCACCGGAACCGGCACCGGTATAGGAACCGGCACCAAGACTTCATATAGCCGCCTCGTCACCGCCAGAACTATTAAGAAAGAGGAAAAGCCTGATGAAACTATGTTGACCAGTAACCTTCTAGCAATGGACACAAAGGAATCAATAACATCGACCATCCTGCAAGTGTACGATACCATAACGGAAGCCAAGCCGAAGATCGAAGTCCTCATAAAGCAGGAGACCAAGCGGAGAAGGAAGGACTATATTTGTCCCACTTGTAAGGTTGACCAACTCACAGATGTGGCATTCCATGCACATCTCAAGATACATCCGCTGGAGTGTCTCACGTGTGGAAAGTGCTTTTTCAGACGGGCGAACTTGGCGTTGCATATCAAAACGCATTTAGGAATTAAGAATTATAAATGCGAGGTGTGCGAGAAGAGGTTCATAACGCGGCAGAAGCTGATGGAGCACCACAACGTGCACACGGGCCGCGCGCCCATCAAGTGCACCATCTGCGACGACACCTTCCGACGATATTCCAATATGGTGCAGCACAGGGACCGGCACCACCTATCGAAGCGTGCCAAGGTGCGCGACTTCGTGTGCCAGTGCGGCGCCGTGTTCCACTCGCGCGCCAAGCTGGTGTGGCACCGCGAGACGCACGACGACAAGCCCAAGGCGTGCCTGTACTGCAGCGACAAGTTCGTGCACGCGTCGTCGCTCACGCGCCACGTGCGCCGCTCGCACAACGAGTTCTTCCTCTCCGACCGGCTCAAGGCCAAGCCCGAGAACGTGCCCTGTCCCGTCTGCAAACAGATATACCTCAGATCAAATCTCCGTGCCCATCTCCAAACCCACAGCGGCAAGCGTCCGTACCTTTGCATCATCTGTAACAAAGCATTCACAACTAAATGGAACCTCAAACTACACCGGTGGACCCACATGAGCCGCTCGGCCAAACCATTCAAATGTAACTTGTGCAAAGGTGCCTTCATTAGACAAACAGAATATATATCACACATGAACGCTCACAAATCAGTACGGCCCTACACCTGCAACTACTGTGGCTGTCAATTCATAAGAAAATATAACTGTCAACGGCACGTGAGGGAACACGAAATGATGAAGAAGTATGTGTGCAAAGTGCCAGAGTGCGGTAAATCTTTCCATAGGAGTTATTATTTGTCTGAACATATGAAGGTACATAGCGGTGCTCGGCCGTTCTCGTGCAATATATGCGGCAAGACTTCGAGCAATAAATCTAATCACAATAAACACGTGAAAATACACCACGCGCGGGAACCGGTCGCTACCGAAGCGTAG
Protein Sequence: MEHLVQCPVCTLYLHNGMTLESHLDTHPKDQVIKALCCLTAKSSSYGSRTSTPLNSERSYRSRSRTPATDDSARWNGSHRSTEHDRYWRRTPSRTPSRTPSRTPKTTPVTNVSRNATPDTRMTDMNYDNSITNSDPQSATSFVMKSDKTQQTYQPASQHTDFDPQYIYYQDQQDEIKYSRSAEYNALDNSNNIFAYNIPTVGTGMKLQPTLMSTAPRKANDLVKILPKPNNILVKPNMGGVQYLTPGVKPLNVVMPPAPAFVQKNVQNNMIMTGSLPTATMQMDTKGMPAQKAANQFNHLTSGSFTPSTTVVTQNSHIIYREMVHNLDGKPFISSMPAVLGGHENVTNVAQASSMYQNVMVVDQFGNTSCMFTTPQQLLPKACPPPMFNENMLVGTGAHLDKTVPNTSDTNKTIMIKVSPIVSSDPIVSCETASTSIPQASCSSRDKKEKPVVEKGEQKCDTPGPSKGLKILSNIKVEVPVQHHKNMVNTVMDLTCSNDPDYLERSESPEKILPDLDDNKTIISDDCTQPSISSSDSVVSHSFSVIKNVGNPPLYKDSSNKSNTVDNKMETEFADSCPVPDLICNEKPSISPCSELSEHCDNSTDRTLISPKPENSQQSQNPLDIHIDKKLQFSTKPFRNNTLRLNNIYVKKNKKVLHIKNAKASSSTVSSKVETEPIPSSSICRSPENFTMNKKQKADRNEKRDKCSVLQTVSIEMVKENDDEHNNFDADTEEQSMDIEPIAPNQSNSNEYATTVDMIHVKEEVNSSNEGVFSNEAPGRVLTPLETLRPINVITYGSMSAGDFDDESNHRELLDLEAASKNKQFVNMMNENYFGDNIYADYFTPDRVEAFDAEREASAFKEGSIGIWGESSQKETESEFVLPNFIHESYKIAESTGLDYSDIGVRGGVGGEVEGCERDSKADVLSESRSEGEAPLNICADERMPPRGELSGQESNGDMESWSGMYSEVTPAVPYDLMARESWVSDDSEMDATEKREALEEALHFPKSTHRQYTCMQCGAKFPSLKEMRAHKSLAHAPATATCSGTGTGTGIGTGTKTSYSRLVTARTIKKEEKPDETMLTSNLLAMDTKESITSTILQVYDTITEAKPKIEVLIKQETKRRRKDYICPTCKVDQLTDVAFHAHLKIHPLECLTCGKCFFRRANLALHIKTHLGIKNYKCEVCEKRFITRQKLMEHHNVHTGRAPIKCTICDDTFRRYSNMVQHRDRHHLSKRAKVRDFVCQCGAVFHSRAKLVWHRETHDDKPKACLYCSDKFVHASSLTRHVRRSHNEFFLSDRLKAKPENVPCPVCKQIYLRSNLRAHLQTHSGKRPYLCIICNKAFTTKWNLKLHRWTHMSRSAKPFKCNLCKGAFIRQTEYISHMNAHKSVRPYTCNYCGCQFIRKYNCQRHVREHEMMKKYVCKVPECGKSFHRSYYLSEHMKVHSGARPFSCNICGKTSSNKSNHNKHVKIHHAREPVATEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00761984;
90% Identity: iTF_01252149;
80% Identity: -