Afla002019.1
Basic Information
- Insect
- Achlya flavicornis
- Gene Symbol
- -
- Assembly
- GCA_947623365.1
- Location
- OX392494.1:6452921-6457864[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.0036 0.23 12.3 1.0 1 20 187 206 187 209 0.92 2 10 0.014 0.91 10.4 0.5 2 23 236 258 235 258 0.95 3 10 0.0032 0.21 12.5 1.7 1 23 280 302 280 302 0.98 4 10 7e-05 0.0045 17.7 1.1 1 23 306 329 306 329 0.97 5 10 0.0012 0.074 13.9 0.1 1 23 334 357 334 357 0.95 6 10 0.016 1 10.3 1.2 2 23 364 386 363 386 0.92 7 10 9.1e-05 0.0058 17.4 6.7 1 23 393 416 393 416 0.98 8 10 0.00053 0.034 14.9 4.1 2 23 423 444 422 444 0.97 9 10 4.7e-07 3e-05 24.5 1.7 1 23 450 472 450 472 0.98 10 10 0.0011 0.072 13.9 6.9 1 23 478 500 478 501 0.96
Sequence Information
- Coding Sequence
- ATGATGACTGTTACTGTTCGCGACCACAGACTGCTATTTGCCGGCAGCTTCAATCAAGGAAACAAGGACTTGATTCCAATTTTTTACCGACTATCCAGCGACACTAGCTCTTCGTTCAATGTTGGTGCTGGCAAGAAACCTTCGGCTTCGGCTGAAACTGGACCTTTTTGGTCGAGGCCGAAGGTTTGGCGAAAATGGCCGAAGCTTCGGTCGGACACTAATAACTGCAGCTTTAGGTACGGAGACCACGACTTCAGCAACTTAGTGGAGGGAGAGGCGAGCCTGCTGGCCAGATTCGCGCCTGGAAAACTGAAGATGCTGCCTACTAGAGAAAGTCTACGTAATATGTGTCCTGACTATGTAAAAGAATTGGATTCCTTGAAAGACAAAACCATAACAGCTGGCATGATTGAATCAATCCTCCACACAGACAGGAAGAAAGAAAGAAAGAAAAAAGATCTATACAACGTCAAAGAGAAAATTGCACATATAATAAATGTATCGACTCTGTtagaaaactgcaatgcaatcgcgtttaaaactaaactgcggtgcgggtacccctgcttttactgcggacaaagatatttcgacctaaaggaattgagagagcatcagccaaaacacgcaaaatccttaatctccaaaatactatcgaaatacacctgcgatactttagtagtttatgcagaaataacaaacttaaaatgctcaatttgtcaccaaaacataccagatctaaacgaattaaaaagtcacctaataaaggaacatgctaagaaaatgtatacagatttctcggacagggttataccgttcaaatataagcaggaaggattcgagtgtcaagtctgtcattttaactttgagactttcggcgcgatagagaaacatatgaattatcactataggaactatgtgtgcgaacaatgtggcacaggctttgtgaccaaccatagactaaaagtccacgttaaatcgcagcataacgaaggtaacttcccatgcggtgaatgcaaaaaggtttacacatctgcgttgagactgaaaacacatttggatgttgttcacaaactgaaaagacgaaataagtgtccgcactgtttggaaacattcgtagattattttacaagacagaaacacatggtagaagtgcatgacgtcaaaccgattttctacaaatgcaacgtatgtgaacacacttttagtagaagatacgggttgacaactcatttaaagcgatgccatttagaacagaaagatgtaaaatgcgtgcattgcaactatacatgcttcagtcaaggacaattaagagctcacatgctaaaacatggcggcgagaaaatatttgaatgtagcgtttgtaagaaatcgtatgcgaggaagaagactttgaaagaacatatgagaatacataataatgacagacgattcaaatgctgtgtctgtgaacaggcgtttgttcagaattgtagtttgaagggacacatgaagactcatcatcgcgaGTATTTAGAAGCGAGGGAATAA
- Protein Sequence
- MMTVTVRDHRLLFAGSFNQGNKDLIPIFYRLSSDTSSSFNVGAGKKPSASAETGPFWSRPKVWRKWPKLRSDTNNCSFRYGDHDFSNLVEGEASLLARFAPGKLKMLPTRESLRNMCPDYVKELDSLKDKTITAGMIESILHTDRKKERKKKDLYNVKEKIAHIINVSTLLENCNAIAFKTKLRCGYPCFYCGQRYFDLKELREHQPKHAKSLISKILSKYTCDTLVVYAEITNLKCSICHQNIPDLNELKSHLIKEHAKKMYTDFSDRVIPFKYKQEGFECQVCHFNFETFGAIEKHMNYHYRNYVCEQCGTGFVTNHRLKVHVKSQHNEGNFPCGECKKVYTSALRLKTHLDVVHKLKRRNKCPHCLETFVDYFTRQKHMVEVHDVKPIFYKCNVCEHTFSRRYGLTTHLKRCHLEQKDVKCVHCNYTCFSQGQLRAHMLKHGGEKIFECSVCKKSYARKKTLKEHMRIHNNDRRFKCCVCEQAFVQNCSLKGHMKTHHREYLEARE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01083620;
- 90% Identity
- iTF_01252105;
- 80% Identity
- -