Basic Information

Gene Symbol
-
Assembly
GCA_030710515.1
Location
JALBCR010002553.1:272059-275502[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 23 1.1e-05 0.0038 19.9 0.2 1 23 13 35 13 35 0.98
2 23 3.7 1.3e+03 2.5 0.7 1 9 41 49 41 49 0.90
3 23 0.016 5.4 10.0 6.0 1 23 56 78 56 78 0.97
4 23 0.018 6.3 9.8 2.0 1 23 87 109 87 109 0.98
5 23 0.21 72 6.4 0.2 1 23 115 137 115 137 0.93
6 23 6e-06 0.0021 20.7 0.7 1 23 143 165 143 165 0.98
7 23 4.8e-07 0.00016 24.2 0.4 1 23 171 193 171 193 0.98
8 23 0.00041 0.14 15.0 3.1 1 23 199 221 199 221 0.97
9 23 0.33 1.2e+02 5.8 0.1 3 23 277 297 275 297 0.92
10 23 0.25 86 6.2 5.5 1 23 328 351 328 351 0.88
11 23 0.0023 0.8 12.6 0.3 1 23 357 379 357 379 0.97
12 23 7e-06 0.0024 20.5 0.9 1 23 385 407 385 407 0.98
13 23 2.8e-05 0.0096 18.6 0.5 1 23 413 436 413 436 0.97
14 23 0.00014 0.049 16.4 1.6 2 23 443 464 442 464 0.98
15 23 9.8e-05 0.034 16.9 1.9 3 23 472 492 471 492 0.98
16 23 2.3e-06 0.0008 22.0 0.7 1 23 498 520 498 520 0.96
17 23 8.1e-07 0.00028 23.5 1.4 1 23 526 548 526 548 0.98
18 23 0.96 3.3e+02 4.3 0.1 1 12 554 565 554 570 0.83
19 23 0.12 41 7.2 1.0 1 21 724 744 724 745 0.95
20 23 0.04 14 8.7 0.2 2 23 752 774 752 774 0.92
21 23 0.0099 3.4 10.6 1.5 3 23 780 800 779 800 0.97
22 23 0.01 3.6 10.5 4.7 1 23 806 829 806 829 0.96
23 23 4e-06 0.0014 21.3 1.9 1 23 834 856 834 856 0.98

Sequence Information

Coding Sequence
ATGCACGAAAAAGCTTCGCACTCGTCCGACCGCTGTTACGTTTGTTCCACTTGCGGCGCGTCGTTTGCAACCAAACCCTACTTAAAATCTCACGAGAGGATACACTCGACCAAGCATAAGTACGAATGCGATAAGTGCGGTCGAGTTCAGCATAAGGGTGTTAGATTTCATTGCGATCGTTGCAAAAAGATTTACACCAACGAGTACTACTTCAAAAAGCATTCGCTGACTCACGACCCGAACTTTGTCAAAAGTGAGTACACGTGCGAAATATGTAACAAAGTGCTGCACTACGGCAGAACTTACGCGAACCACCTCAAAACTCATAAAGGAGAAAACCGACACGTGTGCGAGGTGTGCGGAAAAATCTTAGGATGGACGCAAAGTCTTAAAGATCACATGTTGCTGCATCGCGGTGAGAAACCGTTTATTTGTCAAATATGCGGGAAACGATTTTCGAAAAAGCAGTTGATGGTGGTTCACCAGCGCGTTCACACCCAATCGAAACCATACGCTTGTTTGATCTGCGACAAACGTTTTAGTCAACGAGGCTCTTTGACGGTGCACGTTCGCACCCATACCGGCGAGAAACCGTTCAAATGCAGCATATGTCAGAAAGGCTTCGTCACGAATGGGATGCTCAAGTTGCATTGCAAGACGCACGCCCAGATTGATGTAATTCCGCTGTTAGGATCTGTGACGGAGGAGGATAAGAAATCGGTCATGATTAAGTTGGGTTACAAAAATCCTTTCCATTACGTCCATTGCGATTTCAAAGGTAGGGTTAAACAAAGTAGGATCGGCGATGGCGGGGCTTCTAAATGGACGTGTATCATTTGCAACGAAGGATTGAGCGACAAAAGAACTTTGATCGAACACTATGCGAGTCATAAGAACGAGCAGGAGTGTAAACGCGAAGATGGCCAGGGCGCGTGCGCTATTGAAGACTATTTTAAATGTACGAAACATGGAGAGAACCGCTACGCTTGCCAAGAGTGTAATAAGACTTATAAGAGCTGCTTGTACCTGTGCTTGCATAATTTCAGCGCGCATTCCCAAGATCAACAGTATCGATGCGTGGCTTGCGATTTTGCTACTACAGATCGCAGTAGCCTTAAAGTTCACTTGGACAAGCACGAGGAAGAGTTGAAGTACAAATGTGACATTTgcgacaaaaagttttttaatgccAGTTTATTGGAGGAGCATAAGAGTTCTCACTCGGGAGCGATGCCGTTCCAGTGTGACATTTGCTCGAGAAGCTTTCCGTACGCCAGCTATTTGGTGTCGCACAAGAAGAGTATCCATTCTGAGGCGGTCGTTAATAAATGTGGAATATGTGAAAAGCAATTTGCGCACAGGAAGAGTCTGATTTTGCACGTGAGGTCACATACTGGAGAAAATACCGTTTTGTGCGACATGTGCGGGAAACGGTTGTCTAGTACCGAACATCTGAAACAGCATTTGCGCATTCACACGGGCTACAAGCCTCATGCTTGTTCAGTCTGCGGCAAGGGCTTTGCGAAAAAGAGCAATTTAACTTTACACGAGCGCGTTCATAGCGGGGAGAAGCCTTATGTTTGCGGAGAATGTGGAAAATGTTTTTCTCAACGATCGACTTTGGTGATACACGAGCGGTACCACTCTGGAGAAAGGCCATACAATTGTCCGATGTGCAATAAAGTTCGGCGAAACGTTTCGGTGCTGTCGTTGCGAGGAGCACTTCAAACAACCACGGATTTGTACAACCATTACGAGGTGCACAAAAGTGGTGGTAGTGTCGTTGTCGAAAAGTTGACCGAGATTGAATACAGAGATAGTTCTTCGAACGAGCTTTTGTACATTCTGGACGGGTCTCAGTGCATTAACGAGGTCGTAATCGAGGACGAAGGCGAGATTCGCGATTACGAAAGCGACAGCGGTACAAAAGGCGACGGCGATGGTCAGTTGGAAAGTAAGAAAAGGTATAAGCGGCGGGAGGTCGAGGCATCTGAGAGTTATGGAGAAGACGAGAGCGCTATCGAAGCCATACTGACATCGGAAGCGACTTCTAGCAAAAGCACTCAACCGCTACCTAAGAGTAGGCCGAAACGTCGGCACGAGATACCAGATTTCTCGGCCACAAATTATATTATGTTGAATCCGACAGAGGACTTAGACATCGttcattataaatgtttacGATGCGAACAGTTGTTTATTAGTAAATTCGGGTTTTTTAGGCATATCGAAAAGGGCCGGTGTTATATTAACAGTTGCGACGTGTGTAGTGCTTCATTCGAAAAGAACAGCGAGTTTTACGATCACTATCTCGCCGAACACACCGATAGGGCGATCTGTAACTTTTGCTTTCGAACTTTTATGTACGAAAAGAATGTTAAGGAGCATATGCTTAGGCATTTGGATCAGTTTCGGCATCGGTGCGAGCAGTGCAACAAAGGTTTCTATACTGTGAGGGAGTACAGGAACCATTAcaaaaatcggcacatgggcattagacataaatgtaatgtttgtggACGTTCTTTTGCGGACGAATATTATTTTAAGCGACACGTAGCCACCCACGAAAAGGCTTTGGCctctaaaatacaatttagttcttcattttaa
Protein Sequence
MHEKASHSSDRCYVCSTCGASFATKPYLKSHERIHSTKHKYECDKCGRVQHKGVRFHCDRCKKIYTNEYYFKKHSLTHDPNFVKSEYTCEICNKVLHYGRTYANHLKTHKGENRHVCEVCGKILGWTQSLKDHMLLHRGEKPFICQICGKRFSKKQLMVVHQRVHTQSKPYACLICDKRFSQRGSLTVHVRTHTGEKPFKCSICQKGFVTNGMLKLHCKTHAQIDVIPLLGSVTEEDKKSVMIKLGYKNPFHYVHCDFKGRVKQSRIGDGGASKWTCIICNEGLSDKRTLIEHYASHKNEQECKREDGQGACAIEDYFKCTKHGENRYACQECNKTYKSCLYLCLHNFSAHSQDQQYRCVACDFATTDRSSLKVHLDKHEEELKYKCDICDKKFFNASLLEEHKSSHSGAMPFQCDICSRSFPYASYLVSHKKSIHSEAVVNKCGICEKQFAHRKSLILHVRSHTGENTVLCDMCGKRLSSTEHLKQHLRIHTGYKPHACSVCGKGFAKKSNLTLHERVHSGEKPYVCGECGKCFSQRSTLVIHERYHSGERPYNCPMCNKVRRNVSVLSLRGALQTTTDLYNHYEVHKSGGSVVVEKLTEIEYRDSSSNELLYILDGSQCINEVVIEDEGEIRDYESDSGTKGDGDGQLESKKRYKRREVEASESYGEDESAIEAILTSEATSSKSTQPLPKSRPKRRHEIPDFSATNYIMLNPTEDLDIVHYKCLRCEQLFISKFGFFRHIEKGRCYINSCDVCSASFEKNSEFYDHYLAEHTDRAICNFCFRTFMYEKNVKEHMLRHLDQFRHRCEQCNKGFYTVREYRNHYKNRHMGIRHKCNVCGRSFADEYYFKRHVATHEKALASKIQFSSSF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-