Atri000104.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Abrostola triplasia
Gene Symbol
CTCF
Assembly
GCA_946251925.1
Location
CAMIUJ010000001.1:1589223-1601774[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.0014 0.083 13.5 2.1 1 23 458 480 458 480 0.97
2 11 4.2e-05 0.0025 18.3 1.6 1 23 486 508 486 508 0.97
3 11 0.00011 0.0062 17.1 1.7 1 23 514 537 514 537 0.96
4 11 0.05 2.9 8.7 3.2 1 21 543 563 543 565 0.95
5 11 0.00016 0.0093 16.5 2.7 1 23 571 593 571 593 0.99
6 11 0.00029 0.017 15.7 3.3 1 23 599 621 599 621 0.98
7 11 0.0078 0.46 11.2 0.5 1 23 629 652 629 652 0.96
8 11 0.026 1.5 9.5 4.3 2 23 659 680 658 680 0.96
9 11 0.00019 0.011 16.3 2.5 1 23 686 708 686 708 0.98
10 11 4.7e-06 0.00028 21.3 1.9 1 23 714 737 714 737 0.96
11 11 1.6e-05 0.00096 19.6 4.4 1 23 751 773 751 773 0.97

Sequence Information

Coding Sequence
ATGTATTATTTTGTTTCAGGCGATATCGGCCAGGTCCGTCGACCTAGCCCGGCCAGCCGTGCTTTACACCCTATAGACACTGATCTATATTTAAACCATCAAATACTGAAGTACATACCCTACACCTTACCTGACGAAAATCTGACAAACAGGGCAGCCCCGGCTAGCCAGGAAACCCTGGCGAGCTCGGATACCCTGGCGGTCCCGGACACACTAGTGAGCCCGGACACTCTGGCGAGCCCGGACTCCCTAGTGAGCTCGATCACATTGGCTACCCCGGATGCTACACCGAGCCCGGACACTTTGGCGATTCCGAATACTACAGCGGGCGCGGACAGTTTGACGATCCCGGTTACTACAGCGAGCGCGAACACTTTGGCGGTCCTGGACTCCCTCGAGAACCCTAACCACTTCTCCAGCCCTGACCCGCTCTCCAGCCCTGTACCCCTCTCCAGCCCTGACCCCCTCGACAGCCCTGAACCCCTCGATAGCCCTGACCCCCTCGATATTCCTGATACTCTCGATAGTCCTAACCCCATTGTTAGACCTCGCCCTCTTGAGAGCCCTGACCCCCTTGAGAGCCTTGACCCTCTCGAGAGCACAGACACCCTAGCAAGCTCGGACACACTAGAAAGCTCGACCACACTAGAAAGCTCGAACACCATAGCCTGTCGGGACACCCTCGCAAACTCGGACAGCCTTGCAAGCGAGGGTACTCTAGTAATCCCGGACTCTCTTGCAAACTCGGACAGCCTTGCAAGCGAGGGTACTCTAGTAATCCCGGACACCCTAGTAATCCCGGACAGTGTAACGACCTCTGAAGACACCATGGCAGCCCAGGATAAGAAGGATAAAAATAAACAAGCACTTATACAATCGTACTTAAATCAAGGAGCAACGACTACTGTCATTGCGGTCAATACCGCAAATGATGATGAGTCTGATGCAAGTGGAGTCACATACTTTGTCGATGAAGAAGGAAGATACTACTACCAGCCAGCGGGTGTCAACCAAGGCCTGGTTTCACTCTCTACCGGTGGAGTCAACGATGACAATGAGGCCATCAATGAAGAAGATGACTCAATGATGGTTGACCAAGAGACGGAGAGCTACCAGACTGTCACCCTGGTTCCTTCAGAGTCCAGCACCGGGGAAGTTAGCTATGTGCTTGTTGTGCAGGAGGAAAACAAGCCTGTTGTCAACATTGACATCAATATGGACCAGGAGCCTCCGGAAAGAAAGGTCAACCAGGACGTTTACAACTTTGAGGAGGAAGAAGATGCTGGTGAAGAGCAAAGTGATGACGAGGGAAAAGCAGACGGCAAGCCGAAGGTGCCCAAGCCGCCTCGTGTGAAGCAAGTGCGGCCGCGCTTTGACTGTAACTTCTGCGCTTACTCGAGCTACCGGCGCTACCTTCTTCTTCGCCACATGCGGTCTCACTCAGAAGACCGCCCGCACTCGTGTAATGTGTGTGACCGCGGCTTCAAGACCTTCGCCTCGCTGCAGAACCATGTCAACATGCACAACGGTGTCAAGCCCCACGTGTGCAAGTACTGCAACAGTCCTTTTACCACCTCCGGCGAACTTGTCCGGCACGTGCGTTACAAGCACACTTATGAGAAACCGCACAAGTGCAGCGAGTGCGACTACGCTTCCGTCGAGCTGTCGAAGTTGCGGCGGCATGTGCGGTGCCACACCGGCGAGAGGCCCTACCAGTGTCCTCACTGCACCTACGCGTCTCCGGACACGTTCAAGCTGAAGCGCCATCTCCGCACGCACACCGGGGAGAAGCCGTACAAGTGCGACAGCTGCAGCATGTGCTTCACGCAGTCCAACTCGCTGAAGGCACACAAACTGATACATAATGTGTCCGAGAAGCCGGTTTACGCGTGTGAGTTGTGCCCGGCCAAGTGCGGCCGCAAGACGGACCTGCGGATTCACGTGCAGAAGCTGCACACGTCGGACAAGCCGCTCAAGTGTCGCCGCTGCGGCAAGTCCTTCCCCGACCGGTACTCCTGCAAAGTGCACAATAAGACCCACGAGGGCGAGAAATGCTTCAAGTGCGAGCTGTGCCCGTACGCGTCTACCACTCTGCGGCACCTCAAGACGCACATGCTGAAGCACACCGACGAGAAGCCGTTCGTGTGCGACCAGTGTGATCAGTCCTTCAGGCAGAAGCAGCTGCTGCGTCGCCACCAGAACTTGTACCACAATCCGGATTACGTGCCGAAGCCGCCGAAGGAGAAGAACCACACTTGCCACGAGTGTAAACGCATGTTCGCCCACAAGGGCAACCTGATACGTCACCTTGCTGTCCACGATCCTGAATCGGGCCACCACGAACGTACGCTTGCTCTGAAAATTGGCAGGCAGCGCAAAGTGAAATTCATCGAAGGAGAAATCATGAAGGACATCCACAACCCCGAGCAGGAAGAAGGTACGGAGATGATGAAGATCGAGCTCGGCAACAACGAGCTGAAGCGTGGCGAGCTGGTGACGGTGGCCGATGGCGACGGCCAGCAGTACGTGGTGCTGGAGGTCATCCAGCTGGAGGACGGCACCGAGCAGCAGGTCGCTGTCGTAGCGCCGGACTTCATGAACACCGAGGAAGACGGTGAAGATGAAGAAGAAGAGGAGGATACGGAAGATGTCGTGGAGAAGAAGTTTAAGGTGAAGGAGACGGAGACCGAACGGAGTATTAAACTTGAGAACGACGTCGACACGTGCTTCGGGTTTGATGAGGAGGAGGAAGATCCTGACGAGGATGATTATAACGATAAAGTAGTTTTGCGTTTAGTTTAA
Protein Sequence
MYYFVSGDIGQVRRPSPASRALHPIDTDLYLNHQILKYIPYTLPDENLTNRAAPASQETLASSDTLAVPDTLVSPDTLASPDSLVSSITLATPDATPSPDTLAIPNTTAGADSLTIPVTTASANTLAVLDSLENPNHFSSPDPLSSPVPLSSPDPLDSPEPLDSPDPLDIPDTLDSPNPIVRPRPLESPDPLESLDPLESTDTLASSDTLESSTTLESSNTIACRDTLANSDSLASEGTLVIPDSLANSDSLASEGTLVIPDTLVIPDSVTTSEDTMAAQDKKDKNKQALIQSYLNQGATTTVIAVNTANDDESDASGVTYFVDEEGRYYYQPAGVNQGLVSLSTGGVNDDNEAINEEDDSMMVDQETESYQTVTLVPSESSTGEVSYVLVVQEENKPVVNIDINMDQEPPERKVNQDVYNFEEEEDAGEEQSDDEGKADGKPKVPKPPRVKQVRPRFDCNFCAYSSYRRYLLLRHMRSHSEDRPHSCNVCDRGFKTFASLQNHVNMHNGVKPHVCKYCNSPFTTSGELVRHVRYKHTYEKPHKCSECDYASVELSKLRRHVRCHTGERPYQCPHCTYASPDTFKLKRHLRTHTGEKPYKCDSCSMCFTQSNSLKAHKLIHNVSEKPVYACELCPAKCGRKTDLRIHVQKLHTSDKPLKCRRCGKSFPDRYSCKVHNKTHEGEKCFKCELCPYASTTLRHLKTHMLKHTDEKPFVCDQCDQSFRQKQLLRRHQNLYHNPDYVPKPPKEKNHTCHECKRMFAHKGNLIRHLAVHDPESGHHERTLALKIGRQRKVKFIEGEIMKDIHNPEQEEGTEMMKIELGNNELKRGELVTVADGDGQQYVVLEVIQLEDGTEQQVAVVAPDFMNTEEDGEDEEEEEDTEDVVEKKFKVKETETERSIKLENDVDTCFGFDEEEEDPDEDDYNDKVVLRLV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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